Indian Journal of Public Health Research & Development

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Congenital Malformations Detected at Birth - a Prospective Study in Bangalore


Affiliations
1 Dept. of Anatomy, MRMC, Gulbarga, India
2 Dept. of Physiology, MRMC, Gulbarga, Karnataka, India
     

   Subscribe/Renew Journal


In a prospective study of 4280 births in Vanivilas Hospital, Bangalore Medical College, Bangalore 61 cases of congenital malformations were observed with an Incidence of 14.25/1000 live births. A total of 117 malformations were observed. Among these 95 were major and 22 were of minor type. The central nervous system, gastro-intestinal and multiple system involvement were the commonest with 12 cases each (19.67%), followed by musculoskeletal 11 (18.03%), cardio-vascular 4 (6.56%), genito urinary 02 (3.30%) cases), cutaneous 1 (1.64%) and 07 (11.49%) cases were miscellaneous. Malformations in the new born males were 52.46%, in females it was 45.90% and 1.64% are of ambiguous genitalia thereby showing male preponderance. Maximum of 42 cases (68.85%) were born to non-consanguineous group and 19 cases (31.15%) were to consanguineous couples.

Keywords

Congenital Malformations, Neonate, Consanguinity
Subscription Login to verify subscription
User
Notifications
Font Size


  • Alan C. Stevenson, Harold A. Johnston, patrica stewart MI et al Congenital Malformations: A report of a study of series of consecutive Births in 24 centres. Bull. WHO 1966; 34: 1-127.

  • Arati Choudhury, Geeta Talukder and Archana Sharma. Neonatal congenital malformations in Calcutta. Indian Journal of Pediatrics 1984; 21: 399-405.

  • Mathur BC, Sheila Karan and Vijaya Devi KK. Congenital Malformations in the Newborn. Indian Journal of pediatrics 1975; XII (2): 179-183.

  • Kulshrestha R., Nath LM. and Upadhyaya P. Congenital Malformations in live born infants. A Rural Community. Indian Journal of Pediatrics 1983; 20 : 45-49.

  • Rustin McIntosh, Katharine K merritt, Mary R. Richards et al. The Incidence of Congenital Malformations: A study of 5964 pregnances. Journal of Pediatrics 1954; 14: 505-521.

  • Shanti Ghosh and Lata Bali, Congenital Malformations In the Newborn. Indian Journal of Child Health 1963; 12: 448-452.

  • Mishra PC. and Baveja R. Congenital malformations in the newborn – A prospective study. Indian Journal of Pediatrics 1989; 26 ; 32-35.

  • Goravalingappa JP. and Nashi HK. Congenital malformations in a study of 2398 consecutive births. Indian Journal of Medical Research 1979 : 69 : 140-146.

  • Swain S., Agrawal A. and Bhatia BD. Congenital Malformations at birth. Indian Journal of Pediatrics 1994 ; 31 ; 1187-1191.

  • Vikram Datta and Pushpa Chaturvedi. Congenital Malformations In Rural Maharashtra. Indian Journal of Pediatrics 2000 ; 37 : 998-1001.

  • Philip M Marden, David W Smith and Michael J Donald Congenital anomalies in the newborn infant including minor variations. The Journal of Pediatrics 1964; 64(3): 357-371.

  • Singh M., Jawadi MH., Arya LS. et.al. congenital malformations at birth among live-born infants in Afghanistan, a prospective study. Indian Journal of Pediatrics 1982; 49 : 331-335.

  • Sugunabai NS., Mary Mascarene, Syamalan et.al., An Etiological Study of Congenital Malformation In the New Born. Indian Journal of Pediatrics 1982 ; 19 : 1003-1007.

  • Arjun Singh, Ravinder K Gupta. Pattern of Congenital Anomalies in Newborn: A Hospital Based Prospective Study. JK science. 11 (1); January-March 2009: 34-36

  • Ali, Ahmadzadeh; Zahad, Safikhani; Masoumeh, Abdulahi; Azar, Ahmadzadeh. Congenital malformations among live births at Arvand hospital, Ahwaz, Iran – Aprospective study. Pakistan Journal of Medical Sciences 2008; 24 (1): 33-37

  • Tibrewala NS and Pai PM. Congenital Malformations in the Newborn period. Indian Journal of Pediatrics 1974; XI (6): 403- 407.

  • Ajay Kalra, Kalra K, Sharma V. et.al., Congenital malformations. Indian Journal of Pediatrics 1984 ; 21 : 945-950.

  • Thirumalaikolundusubramanian P. and Jayaprakash CA. Congenital Anomalies and sex of the baby. Indian Journal of Pediatrics 1985; 22 ; 75.

  • Zilfalil BA. and Rowani MR. Online Birth Defects in Newborn at Hospital Universiti sains Malaysia, Kelantan. Web page http:/ uia4.tripod.com/Vol2-No-1/Vol2-No1-B3.htm

  • Radha Rama Devi A., Appaji Rao N, and Bittles AH., Inbreeding in the state of Karnataka, South India. Journal of Human Heridity 1982: 32 ; 8-10.

  • Kulkarni ML. and Mathew Kurian. Consanguinity and the effect on fetal growth and development: A South Indian Study. Journal of Medical Genetics 1990; 27: 348-352.

  • Sibert J.R., Malati Jadhav and Inbaraj S.G., Petal growth and parental Consanguinity. Archieves of Disease in Childhood. 1979; 54:317-319.


Abstract Views: 260

PDF Views: 0




  • Congenital Malformations Detected at Birth - a Prospective Study in Bangalore

Abstract Views: 260  |  PDF Views: 0

Authors

Dinanath K. Pujari
Dept. of Anatomy, MRMC, Gulbarga, India
Ashwini D. Pujari
Dept. of Physiology, MRMC, Gulbarga, Karnataka, India

Abstract


In a prospective study of 4280 births in Vanivilas Hospital, Bangalore Medical College, Bangalore 61 cases of congenital malformations were observed with an Incidence of 14.25/1000 live births. A total of 117 malformations were observed. Among these 95 were major and 22 were of minor type. The central nervous system, gastro-intestinal and multiple system involvement were the commonest with 12 cases each (19.67%), followed by musculoskeletal 11 (18.03%), cardio-vascular 4 (6.56%), genito urinary 02 (3.30%) cases), cutaneous 1 (1.64%) and 07 (11.49%) cases were miscellaneous. Malformations in the new born males were 52.46%, in females it was 45.90% and 1.64% are of ambiguous genitalia thereby showing male preponderance. Maximum of 42 cases (68.85%) were born to non-consanguineous group and 19 cases (31.15%) were to consanguineous couples.

Keywords


Congenital Malformations, Neonate, Consanguinity

References