Indian Journal of Public Health Research & Development

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Comparative Analysis of Variation in Intraocular Tension with Vecuronium Bromide and Atracurium Besylate: a Prospective Study


Affiliations
1 Department of Anaesthesiology, Saraswathi Institute of Medical Sciences, Hapur, India
2 Department of Ophthalmology, Saraswathi Institute of Medical Sciences, Hapur, India
3 Department of Surgery, Saraswathi Institute of Medical Sciences, Hapur, India
     

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Intraocular pressure is the pressure exerted by the contents of the eye against its containing wall. During general anaesthesia, the intraocular pressure can increase, rendering problems in ophthalmic surgery especially surgery on the eye bulb. Pre-treatment with non-depolarising muscle relaxant prevents fasciculation and so the intraocular pressure does not rise. This is a prospective randomized study of 100 patients divided into two equal groups, where we have compared the effect of vecuronium bromide and atracurium besylate on intraocular pressure. The intraocular pressure was measured before surgery, at the time of intubation and at every 10 minutes interval during surgery. All the data were analysed statistically using unpaired student t test. We concluded that vecuronium bromide has better control over intraocular pressure as compared to atracurium besylate.

Keywords

Vecuronium Bromide, Atracurium Besylate, Intraocular Pressure
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  • Gold Smith E. An evolution of succinylcholine and gallamine as muscle relaxants in relation to intraocular tension.Anaesth. Analog.1967.46:557.

  • Hollyoway KB. Control of eye during general anaesthesia for intraocular surgery. Br J Anaesth 1980,52:671

  • Mirakhur RK, Shepherd WFI, Lavery A, Elliot P. The effect of vecuronium on intraocular pressure. Anaesthesia 42.1987:944- 46.

  • Al-Albarek MH, Samuel JR. Further observation on the effect of general anaesthesia on intraocular pressure in man. Br J Anaesth. 1974,46:756-59.

  • Samuel JR, Beaugie A. Effect of CO2 on intraocular pressure in man during general anaesthesia. Br. J Ophthal.1974:58:62.

  • James N, Mc Galliard, Gavin G, Lavery FFARCS, William FI, Shepherd FRCS. The effect of atracurium on intraocular pressure during steady state anaesthesia and rapid sequence induction: a comparison with succinylcholine. Can. Anaesth Soc J.1986.33(4):437-42.

  • Jantzaj JP, Hackett GH, Eradmannk, Earnshow G. Effect of vecuronium on intraocular pressure.Br J Anaesth. 1986:59:433-6.

  • Payne JP, Hugas R. Evolution of atracurium in anaesthetized man. Br J Anaesth.1981,53:45.

  • Mayer EF, Singer P, Otto A. A controlled study of the effect of succinylcholine on intraocular pressure. Anaesthesiology. 1980,53:72.

  • Maharaj RJ, Humphery D, Kaplon N. Effect of atracurium on intraocular pressure. Br J Anaesth. 1980,52:459-63.

  • Murphy DF, Eustace P, Unwin A, Magner JB. Atracuriun and intraocular pressure. 1985,69:673-75.


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  • Comparative Analysis of Variation in Intraocular Tension with Vecuronium Bromide and Atracurium Besylate: a Prospective Study

Abstract Views: 258  |  PDF Views: 0

Authors

Shailja Sharma
Department of Anaesthesiology, Saraswathi Institute of Medical Sciences, Hapur, India
Arati Srivastava
Department of Anaesthesiology, Saraswathi Institute of Medical Sciences, Hapur, India
Sharad Goel
Department of Anaesthesiology, Saraswathi Institute of Medical Sciences, Hapur, India
Vikrant Sharma
Department of Ophthalmology, Saraswathi Institute of Medical Sciences, Hapur, India
Ashutosh Niranjan
Department of Surgery, Saraswathi Institute of Medical Sciences, Hapur, India

Abstract


Intraocular pressure is the pressure exerted by the contents of the eye against its containing wall. During general anaesthesia, the intraocular pressure can increase, rendering problems in ophthalmic surgery especially surgery on the eye bulb. Pre-treatment with non-depolarising muscle relaxant prevents fasciculation and so the intraocular pressure does not rise. This is a prospective randomized study of 100 patients divided into two equal groups, where we have compared the effect of vecuronium bromide and atracurium besylate on intraocular pressure. The intraocular pressure was measured before surgery, at the time of intubation and at every 10 minutes interval during surgery. All the data were analysed statistically using unpaired student t test. We concluded that vecuronium bromide has better control over intraocular pressure as compared to atracurium besylate.

Keywords


Vecuronium Bromide, Atracurium Besylate, Intraocular Pressure

References