Indian Journal of Public Health Research & Development

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Prevalence of ABO and Rhesus Blood Groups among Blood Donors


Affiliations
1 Dept. of Pathology, S.S. Institute of Medical Sciences & Research Centre, Davangere, Karnataka-577 005, India
2 Dept. of Pathology, SSIMS & RC, Davangere, Karnataka, India
     

   Subscribe/Renew Journal


Background: ABO and Rhesus (Rh) blood group antigens are hereditary characters and are useful in population genetic studies, in resolving medico-legal issues and more importantly for the immunologic safety of blood during transfusion.

Objectives: To document the distribution pattern of the ABO and Rh blood groups among blood donors in and around Davangere (Karnataka).

Methods: The distribution of ABO and Rh blood group was analyzed among 19,413 blood donors, over a period of 5 years (2005 to 2009). The age group and sex of donors, frequency of ABO blood groups and Rh status were calculated.

Results: The predominant donors belonged to the age group between 18-35 years (86.18%). Male to female ratio among donors was 86:1. The most prevalent blood group was O (36.76%), followed by group B (29.85%) and group A (26.15%). The least common blood group was AB (7.24%). The prevalence of Rh positive and negative distribution in the studied population was 94.48 and 5.52% respectively. The highest frequency of coexisting ABO-Rh phenotypes was that of O positive (34.67%) followed by B positive (29.85%) and A positive (26.15%).

Conclusion: Knowledge of frequencies of the different blood groups is very important for blood banks and transfusion service policies that could contribute significantly to the National Health System.


Keywords

Blood Groups, ABO, Rhesus, Phenotypes, Blood Donors
Subscription Login to verify subscription
User
Notifications
Font Size


  • International Society of Blood Transfusion (ISBT). “Table of blood group systems”. Oct 2008, http:/ /ibgrl.blood.co.uk/isbt

  • Landsteiner K. Zur Kenntnis der antifermentativen, lytischen und agglutinierenden Wirkungen des Blutserums und der Lymphe. Zentralblatt Bakteriologie 1900;27:357-62.

  • Landsteiner K, Wiener AS. An agglutinable factor in human blood recognized by immune sera for rhesus blood. Proc Soc Exp Biol Med 1940;43:223- 224.

  • Reid ME, Calhoun L, Petz LD. Erythrocyte antigens and antibodies. In: Lichtman M, Beutler E, Kipps TJ, Seligsohn U, Kaushansky K, Prchal JK. Editors. Williams hematology. 7th ed. McGraw-Hill Medical publishing division:New York;2006. pp 2119-2136.

  • Blaney KD, Howard PR. editors. ABO and H group systems and secretor status. In :Basic and applied concepts of immunohematology. 2nd ed. Mosby Elsevier:Missouri; 2009. pp.78-107

  • Mourant AE, Kopec Ada C, Damaniewssta - Sobczak K. editors. Distribution of Human blood groups and other polymorphism. 2nd ed. Oxford University Press:London;1976.

  • Enosolease ME, Bazuaye GN. Distribution of ABO and Rh-D blood groups in the Benin area of Niger-Delta: Implication for regional blood transfusion. Asian J Transf Sci 2008; 2(1):3-5.

  • Barret KE, Barman SM, Boitano S, Brook HL. Editors. Blood types. In: Ganong’s Review of Medical Physiology. 23rd ed. Tata McGraw Hill: New York; 2010:527-530.

  • Knowles S, Regan F. Blood cell antigens and antibodies, erythrocytes, platelets and granulocytes. In: Lewis SM, Bain BJ, bates I. Editors. Practical hematology. 10th ed. Churchill Livingstone;:Philadelphia; 2006. pp 481-522.

  • Reid ME, Lomas-Frances C. The blood group antigens facts book. Academics Press: SanDiego;1997.

  • Technical manual. In: Vengelen-Tyler, editor. 12th ed. American Association of BloodBanks: Bethesda MD;1996.

  • Polesky HF, Roby RK. Blood group, human leucocytes antigens and DNA polymorphism in Parentage and forensic testing. In:McPherson RA, Pincus MR. editors. Henry’s clinical diagnosis and management by laboratory methods. 21st ed. Saunders:Philadelphia;2007. pp 1340-1349.

  • Ahad MA, Bakar MA, Ahsan HAM. Pattern of ABO and Rhesus (Rh) blood group among blood donors. Taj 2002;15(2):68-70.

  • Periyavan A, Sangeetha SK, Marimuthu P, Manjunath BK, Seema. Distribution of ABO and Rhesus-D groups in and around Bangalore. Asian J Transfus Sci 2010;4(1):41.

  • JaiPrabhakar SC, Gangadhar MR. Study of ABO and Rh (D) blood groups among Gangadikara Vokaligas of Mysore. Anthropologist 2009;11(1):63-64.

  • Prabhakar SCJ, Gangadhar MR. Reddy KR. ABO and Rh (D) blood groups among the Vishwakarmas of Mysore district, Karnataka. Anthropologist 2005;7(1):71-72.

  • Reddy KSN, Sudha G. and Rh (D) blood groups among the desuri Reddis of Chittoor District, Andhra Pradesh. Anthropologist, 2009;11(3):237- 238.

  • Das PK, Nair SC, Harris VK, Rose D, Mammen JJ, Bose YN, Sudarsanam A. Distribution of ABO and Rh-D blood groups among blood donors in a tertiary care centre in South India. Trop Doct. 2001;31(1):47-8.

  • Wadhwa MK, Patel SM, Kothari DC, Pandey M, Patel DD. Distribution of ABO and Rhesus-D groups in Gujarat, India: a hospital based study. Indan J Ped Oncol 1998; 19 (4):137-141.

  • Sidhu S. Distribution of the ABO Blood Groups and Rh(D) Factor Among the Scheduled Caste Population of Punjab. Anthropologist 2003; 5: 203-204.

  • Hammed A, Hussain W, Ahmed J, Rabbi F, Qureshi JA. Prevalence of Phenotypes and Genes of ABO and Rhesus (Rh) Blood Groups in Faisalabad, Pakistan. Pak J Biol Sci 2002; 5: 722- 724.

  • Pramanik T, Pramanik S. Distribution of ABO and Rh blood groups in Nepalese medical students: a report. East Mediterr Health J. 2000 Jan;6(1):156- 8.

  • Bahaj AA. ABO and Rhesus Blood Groups Distribution In Hadhramout Population. Hadhramout for Studies & Researches 2003; 4: 52-58.

  • Boskabady MH, Shademan A, Ghamami G, Mazloom R. Distribution of Blood Groups Among Population in the city of Mashhad (North East of Iran). Pak J Med Sci 2005; 21: 194-198.

  • Sarhan MA, Saleh KA, Bin-Dajem SM. Distribution of ABO blood groups and rhesus factor in Southwest Saudi Arabia. Saudi Med J 2009; Vol. 30 (1): 116-119

  • Al-Arrayed S, Shome DK, Hafadh NAS et al. ABO Blood Group and Rh-D Phenotypes in Bahrain: Results of Screening School Children and Blood Donors. Bahrain Med Bull 2001;23(3):112-15.

  • Australian red cross society. Available from: http://www.donateblood.com.au/all-aboutblood/ blood-types

  • Racial & ethnic distribution of ABO blood types. Last revised on 07/13/2008. Available From: http://www.bloodbook.com/worldabo. html

  • Nanu A, Thapliyal RM. Blood group gene frequency in a selected north Indian population. Indian J Med Res. 1997;106:242-6.


Abstract Views: 344

PDF Views: 0




  • Prevalence of ABO and Rhesus Blood Groups among Blood Donors

Abstract Views: 344  |  PDF Views: 0

Authors

C. M. Mallikarjuna Swamy
Dept. of Pathology, S.S. Institute of Medical Sciences & Research Centre, Davangere, Karnataka-577 005, India
P. B. Basavaraj
Dept. of Pathology, SSIMS & RC, Davangere, Karnataka, India
G. U. Kavitha
Dept. of Pathology, SSIMS & RC, Davangere, Karnataka, India
P. Shashikala
Dept. of Pathology, SSIMS & RC, Davangere, Karnataka, India

Abstract


Background: ABO and Rhesus (Rh) blood group antigens are hereditary characters and are useful in population genetic studies, in resolving medico-legal issues and more importantly for the immunologic safety of blood during transfusion.

Objectives: To document the distribution pattern of the ABO and Rh blood groups among blood donors in and around Davangere (Karnataka).

Methods: The distribution of ABO and Rh blood group was analyzed among 19,413 blood donors, over a period of 5 years (2005 to 2009). The age group and sex of donors, frequency of ABO blood groups and Rh status were calculated.

Results: The predominant donors belonged to the age group between 18-35 years (86.18%). Male to female ratio among donors was 86:1. The most prevalent blood group was O (36.76%), followed by group B (29.85%) and group A (26.15%). The least common blood group was AB (7.24%). The prevalence of Rh positive and negative distribution in the studied population was 94.48 and 5.52% respectively. The highest frequency of coexisting ABO-Rh phenotypes was that of O positive (34.67%) followed by B positive (29.85%) and A positive (26.15%).

Conclusion: Knowledge of frequencies of the different blood groups is very important for blood banks and transfusion service policies that could contribute significantly to the National Health System.


Keywords


Blood Groups, ABO, Rhesus, Phenotypes, Blood Donors

References