Indian Journal of Public Health Research & Development

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Site Distribution of Different Types of Cutaneous Malignancy


Affiliations
1 Department of Pathology, S. S. Institute of Medical Sciences & Research Centre, "Jnanashankara". NH - 4, Bypass road, Davangere - 577 005, Karnataka, India
2 Department of Pathology, S.S. Institute of Medical Sciences and Research Center, Davangere, India
     

   Subscribe/Renew Journal


Background: Dermatological malignancies are relatively uncommon. Since the investigation, at an individual level, of various aspects of lifetime sun exposure, however, remains difficult, comparison of the site distribution and age pattern of different types of skin cancer can be an important source of aetiological clues. This study sought to evaluate the site distribution and age pattern of three main types of skin cancer in our setting.

Methods: The present study is a descriptive analysis of three main skin cancers seen in a tertiary hospital in Davangere. Histologically diagnosed various skin cancers i.e. malignant melanoma (MM), basal-cell carcinoma (BCC) and squamous-cell carcinoma (SCC) from January 2005 to December 2009 were reviewed and analyzed according to age, gender and site of distribution.

Results: During the study period forty tissue samples received were histologically confirmed to be of common primary skin cancers. The ages of the patients ranged from 18 and 80 years (mean: 51.4years). Squamous cell carcinoma (SCC) was the most common malignancy consisting of 26 (65 %) cases followed by melanoma with 9 (22.5%) cases and basal cell carcinoma (BCC) with 5 (12.5%) cases. The most common incidence was among the age group 40-60 years with 20(50%) cases detected. The head and neck was the commonest site of involvement for SCC and BCC, whereas for melanoma it was lower extremities.

Conclusion: Squamous cell carcinoma, Basal cell carcinoma and malignant melanoma constitute three main histotypes of skin cancer. SCC and BCC compared to malignant melanoma affect body locations which are usually sun exposed. Age-related behavior (i.e., another indirect indicator of duration of exposure to UV light) is consistent with the anatomical distribution of skin cancer.


Keywords

Squamous Cell Carcinoma, Basal Cell Carcinoma, Malignant Melanoma, Site Distribution
Subscription Login to verify subscription
User
Notifications
Font Size


  • Franceschi S, Levi F, Randimbison L, Vecchia CL. Site distribution of different types of skin cancer: new aetiological clues. Int J Cancer 1996; 67:24-28.

  • Krickera, Armstronbg K, Englishd R, Heenanp J. Adose-response curve for sun exposure and basal-cell carcinoma. Int J Cancer 1995; 60:482- 488.

  • Armstrong K. Epidemiology of malignant melanoma: intermittent or total accumulated exposure to the sun? J dermatol Surg Oncol 1988; 14:835-849.

  • Levi F, Franceschi S, Randimbison L, Vecchia CL. Trends of skin cancer in the Canton of Vaud, 1976-92. Br J Cancer 1995; 72:1047-1053.

  • Moan J, Dahlback A. The relationship between skin cancers, solar radiation and ozone depletion. Br J Cancer 1992; 65:916-921.

  • Osterlind A, Jensen KH, Jensen OM. Incidence of cutaneous malignant melanoma in Denmark 1978-1982. Anatomic site distribution, histologic types, and comparison with non-melanoma skin cancer. Br J Cancer 1988; 58:385-391.

  • Kaldorj, Shuggd, Youngb, Dwyert, WANG YG. Non-melanoma skin cancer: ten-year experience of cancer-registry based surveillance. Int J Cancer 1993; 53:886-891.

  • Asuquo ME, Otei O, Umana A, Bassey I, Ebughe G. Skin malignancy of the head and neck in Calabar, Southern Nigeria. European J plastic surgery 2010; 33:87-89

  • Laishram RS, Banerjee A, Punyabati P, Sharma DC. Pattern of skin malignancies in Manipur, India: A 5-year histopathological review. J Pakistan Association of Dermol 2010; 20: 128-132.

  • Crombie ki. Distribution of malignant melanoma on the body surface. Br. J. Cancer 1981; 43:842

  • Cutanee T, Calaber, Sud Nd. Skin malignancies in Calabar, Southern Nigeria. J. Afr. Cancer 2009; 1:159-163

  • Deo SV, Sidhartha H, Shukla NK et al. Surgical management of skin cancers: experience from a regional cancer centre in North India. Ind J Cancer 2005; 42:145-150.

  • Ochicha O, Edino ST, Mohamed AZ, Umar AB: Dermatological malignancies in Kano, Nigeria: a histopathological review. Annal African Med 2004; 3:188-191.

  • Al-Thobhani AK, Raja YA, Norman TA.The pattern and distribution of malignant neoplasms among Yemeni patients. Saudi Med J 2001; 22: 910-913.

  • Alakloby OM, Bukhari IA, Shawarby MA. Histopathological pattern of non melanoma skin cancers at King Fahd Hospital of the University in the Eastern Region of Saudi Arabia during the years1983-2002. Cancer Ther 2008; 6:303-306.

  • Al-Maghrabi JA, Al-Ghamdi AS, Elhakeem HA. Pattern of skin cancer in south western Saudi Arabia. Saudi Med J 2004; 25: 776-779.


Abstract Views: 261

PDF Views: 0




  • Site Distribution of Different Types of Cutaneous Malignancy

Abstract Views: 261  |  PDF Views: 0

Authors

A. Manjula
Department of Pathology, S. S. Institute of Medical Sciences & Research Centre, "Jnanashankara". NH - 4, Bypass road, Davangere - 577 005, Karnataka, India
P. Shashikala
Department of Pathology, S.S. Institute of Medical Sciences and Research Center, Davangere, India
B. N. Sandhya Lakshmi
Department of Pathology, S.S. Institute of Medical Sciences and Research Center, Davangere, India

Abstract


Background: Dermatological malignancies are relatively uncommon. Since the investigation, at an individual level, of various aspects of lifetime sun exposure, however, remains difficult, comparison of the site distribution and age pattern of different types of skin cancer can be an important source of aetiological clues. This study sought to evaluate the site distribution and age pattern of three main types of skin cancer in our setting.

Methods: The present study is a descriptive analysis of three main skin cancers seen in a tertiary hospital in Davangere. Histologically diagnosed various skin cancers i.e. malignant melanoma (MM), basal-cell carcinoma (BCC) and squamous-cell carcinoma (SCC) from January 2005 to December 2009 were reviewed and analyzed according to age, gender and site of distribution.

Results: During the study period forty tissue samples received were histologically confirmed to be of common primary skin cancers. The ages of the patients ranged from 18 and 80 years (mean: 51.4years). Squamous cell carcinoma (SCC) was the most common malignancy consisting of 26 (65 %) cases followed by melanoma with 9 (22.5%) cases and basal cell carcinoma (BCC) with 5 (12.5%) cases. The most common incidence was among the age group 40-60 years with 20(50%) cases detected. The head and neck was the commonest site of involvement for SCC and BCC, whereas for melanoma it was lower extremities.

Conclusion: Squamous cell carcinoma, Basal cell carcinoma and malignant melanoma constitute three main histotypes of skin cancer. SCC and BCC compared to malignant melanoma affect body locations which are usually sun exposed. Age-related behavior (i.e., another indirect indicator of duration of exposure to UV light) is consistent with the anatomical distribution of skin cancer.


Keywords


Squamous Cell Carcinoma, Basal Cell Carcinoma, Malignant Melanoma, Site Distribution

References