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Safety and Efficacy of PGE2 Gel (Cerviprime) for Induction of Labour in Term Prelabour Rupture of Membranes, with Special Referrence to its Feto-maternal Complications


Affiliations
1 Department of Obstetrics and Gynaecology, Subharti Medical College, Meerut, India
2 Department of Obstetrics and Gynaecology, RNT Medical College, Udaipur, India
3 Department of Community Medicine, Saraswathi Medical College, Ghaziabad, India
     

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This study evaluated the safety and efficacy of PGE2 gel in 100 patients for induction of labour in term PROM and compared it with control of 100 patients. Mean duration of latent phase, mean total duration of labour and mean admission-delivery interval, rate of Caesarian section, Incidence of fetal and neonatal morbidity was statistically decreased as compared with control.

Keywords

PGE2 Gel (Cerviprime), Term Prom, Feto-Maternal Complications
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  • Akhtar M.S., Deacon I.A., Wren F. (1980). J of Obstet & Gynaecol India 30:81.
  • Akyol D. Mungan T, Unsal A. (1999) Aust NZ J Obstet Gynaecol 1999 Aug.; 39(3) : 291-5.
  • Anjana Devi. Complication of PROM : Chorioamnionitis, PPH, Puerperal Infections. J of Obstet and Gynaecol, India 1996; 46:63.
  • Atlay R.D., Sutherest JR. (1970) Am. J. Obstet & Gynaecol 108 : 993.
  • Averette HE, Hopman B.C., Fergusson (1963) Am. J Obstet & Gynaecol 87 : 226.
  • Bada MDS, Henxetta. Asphyxia Neonatorum. Thepedeart Clin North Am 1977; 24: 3-91.
  • Ben Haroush A, Kalpan B, Bar J (2004) Am J of Obstet and Gynaecol. 2004 July21(5) 263-8.
  • Benedetto C, Tibaldi C, Sozzani P, (2004) J Maternofetal Neonatal Med 2004 Nov; 16 Suppl. 2:9-12.
  • Bernstein P, Leland N, Gurland P, Yare D (1987) Am J Obstet and Gynaecol 156:336-40.
  • Bilgin T, Kadioglu M. (2003) J Mater Fatal Neonatal Med. 2003 Sep. 14(3) : 158-62.
  • Bishop E.H. (1964) Obset & Gynaecol 24 : 226-268.
  • Brosen I. Gordon H. (1965) Br. J. of Obstet and Gynaecol 72:342.
  • Deborah A, Ray MD, Thomas J, Yarite MD (1992) Am J Obstet and Gynaecol 166:836-43.
  • Goeschen K. (1989) Am. J. Perinatol (1989) Apr: 6(2) : 181-4.
  • Goes K. Premature Rupture of Foetal Membrances at Term : Indication of Labour with Endocervical Prostaglandin E2i Gel or Intravenous Oxytocin Am J Perinatol 1989 Apr; 6(2) : 181-4.
  • Gonen R, Samberg I, Degani S. Intracervical Prostaglandin E2 for induction of labour in patients with premature rapture of mambranes and an unripe cervix. Am. J Perinatol. 1994 Nov;11(6):436-8.
  • Granstorm L., Ekman G, Ulinstan U; Acta Obstet. Gynecol Scand. 1987;66(5): 429-31.
  • Hidar S, Bibi M, Jerbi M, Bouguizene S, Khairi H. (2000) J. Gynaecol Obstet. Biol Reprod. (Paris) 2000 Oct.; 29(6) : 607-13.
  • Kiilholma P, Gronroos M. (1984) Obstet and Gynaecol Invest 17 : 194 (Quoted From McGregor,1996)
  • Klebanoff MA, Regan J.A. (1995) Am. J. Obstet & Gynaecol 172;658
  • Kovavisarach E., Sermask P. (2000) Aust NZ J. Obstet Gynaecol, 2000 Feb; 40(1) : 30-2
  • Lettau R, Hege G, Steldinger R. Premature rupture of foetal mambranes at term: an indication for induced labour with prostaglandis? Zentralbl Gynkol. 1995; 117(3) : 121-5
  • Lettau R., Hege G., Steldinger R, Zentralbl Gynkol (1995); 117(3) : 121-5
  • Malik N, Gittens L, Gonzzalez D, Bardeguez A, Ganesh V, Apuzzio Clinical amnionitis and endomentritis in patients with premature rupture of mambranes: endocervical prostaglandin E2 gel versus oxytocin for induction of labour. J. Obstet Gynaecol. 1996 Oct;88 (4 Pt 1):540-3
  • Miekle SF, Biselle ME: Freedman (1992). Obstet & Gynaecol 1992 July; 80(1) : 76-9
  • Milasinovic L, Redeka G. (1997) : Med. Pregi. 1997 May- June; 50(5-6) : 175-80
  • Nirmala Pandey (2001) Obstet & Gynaecol TODAY (2003) Vol. VIII(9) 24-27.
  • Sanyal M.K. (1990) Indian J of Obstet & Gynaecol 40;623.
  • Thakur U, Maitra N, Baxi S, Hazra N (1995) Indian J Matern Child Health 1995 Jan-Mar 6(1); 14-6. 30. Zamzami TY (2005) Arch Gynaecol Obstet 2005 Oct. 6; 1-5.

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  • Safety and Efficacy of PGE2 Gel (Cerviprime) for Induction of Labour in Term Prelabour Rupture of Membranes, with Special Referrence to its Feto-maternal Complications

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Authors

Kriti Bhatnagar
Department of Obstetrics and Gynaecology, Subharti Medical College, Meerut, India
Usha Rani Sharma
Department of Obstetrics and Gynaecology, RNT Medical College, Udaipur, India
Manjul Bhatnagar
Department of Community Medicine, Saraswathi Medical College, Ghaziabad, India

Abstract


This study evaluated the safety and efficacy of PGE2 gel in 100 patients for induction of labour in term PROM and compared it with control of 100 patients. Mean duration of latent phase, mean total duration of labour and mean admission-delivery interval, rate of Caesarian section, Incidence of fetal and neonatal morbidity was statistically decreased as compared with control.

Keywords


PGE2 Gel (Cerviprime), Term Prom, Feto-Maternal Complications

References