Triamcinolone Acetonide Phonophoresis versus Transcutanous Electrical Nerve Stimulation in the Treatment of Post-burn Pruritus - A Randomised Controlled Study
Subscribe/Renew Journal
Methodology: Forty patients with post burn pruritus participated and completed the study. The patients were randomized into two groups of equal number. TAP group: received Triamcinolone Acetonide Phonophoresis, and TENS group received Transcutaneous Electrical Nerve Stimulation.
Results: Revealed a highly significant differences pre and post treatment in TAP and TENS group as regard to degree of pruritus ( p values < 0.05 ). Also the results of the study revealed no significant differences between both groups post treatment ( p values > 0.05 ).
Conclusion: We concluded that triamcinolone acetonide phonophoresis as well as transcutanous electrical nerve stimulation may prove to be a useful modality for the treatment of post burn pruritus with no significant differences between them.
Keywords
- Goutos I, Dziewulski P, Richardson PM. Pruritus in burns: review article; J Burn Care Res. 2009 Mar-Apr;30(2):221-8.
- Moses S. Pruritus. Am Fam Physician (2003); 68(6): 1135-42.
- Edgar, D., & Brereton, M. Rehabilitation after burn injury.BMJ;(2004); 329(7461), 343-345.
- Polat BE, Hart D, Langer R, Blankschtein D. Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends. J Control Release. 2011 Jun 30;152(3):330-48.
- Ganz EC, Griffin CE, Keys DA, Flatgard TA. Evaluation of methylprednisolone and triamcinolone for the induction and maintenance treatment of pruritus in allergic cats: a doubleblinded, randomized, prospective study. Vet Dermatol. 2012 Jun 11. doi: 10.1111/j.1365- 3164.2012.01058.x.
- Whitaker C. The use of TENS for pruritus relief in the burns patient: an individual case report. J Burn Care Rehabil ( 2001);22:274–6.
- S. Elman, L.S. Hynan V. Gabriel,† and M.J. Mayo; The 5-D itch scale: a new measure of pruritus; Br J Dermatol;(2010); March; 162(3): 587–593.
- Yosipovitch G, Zucker I, Boner G, et al. A questionnaire for the assessment of pruritus: validation in uremic patients. Acta Derm Venereol (Stockh) (2001);81:108–11.
- Van der Linden MW, Penning-van Beest FJ, Nijsten T, Herings RM “Topical corticosteroids and the risk of diabetes mellitus: a nested casecontrol study in the Netherlands”. Drug Saf; (2009); 32 (6): 527–37.
- LeFevre C, Hoffstetter S, Meyer S, Gavard J.Management of lichen sclerosus with triamcinolone ointment: effectiveness in reduction of patient symptom scores. J Low Genit Tract Dis. (2011) Jul;15(3):205-9.
- Kelly RA, Foster DC, Woodruff JD. Subcutaneous injection of triamcinolone acetonide in the treatment of chronic vulvar pruritus. Am J Obstet Gynecol. 1993 Sep;169(3):568-70.
- Lagro-Janssen AL, Sluis S. Effectiveness of treating non-specific pruritus vulvae with topical steroids: a randomized controlled trial. Eur J Gen Pract. (2009);15(1):29-33.
- Amit, J. and Jaideep, R., Sonicated transdermal drug transport. J. Control. Release, 83, 13-22 (2002).
- Yang JH, Kim DK, Kim TY, Kim GY, Shin SC. Antiinflammatory effects by transdermal application of triamcinolone acetonide gel using phonophoresis in rats. Int J Pharm. 2005 Sep 30; 302(1-2):39-46.
- Yüksek J, Sezer E, Aksu M, Erkokmaz U Transcutaneous electrical nerve stimulation for reduction of pruritus in macular amyloidosis and lichen simplex. J Dermatol 2011 Jun; 38(6): 546-552.
- Monk B E Transcutaneous electronic nerve stimulation in the treatment of generalized pruritus. Clinical and Experimental Dermatology; 1993; 18(1): 67-8.
- Cc Lyon1, N Howlett1 and Pv Harrison1† The effects of transcutaneous nerve stimulation on pruritus in dermatological patients journal of dermatological treatment 1998, Vol. 9, No. 1 , Pages 21-23
- Engin B, Tufekci O, Yazici A, Ozdemir M. The effect of transcutaneous electrical nerve stimulation in the treatment of lichen simplex: a prospective study. Clin Exp Dermatol. 2009 Apr;34(3):324-8. Epub 2009 Jan 23.
- William Yuk Ming Tanga, Loi Yuen Chana, Kuen Kong Loa, Tze Wai Wongb Evaluation on the Antipruritic Role of Transcutaneous Electrical Nerve Stimulation in the Treatment of Pruritic Dermatoses Dermatology 1999;199:237-241.
Abstract Views: 510
PDF Views: 0