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Management of Patients With Concurrent Hypertension and Osteoarthritis of the Knee: Comparative Effect of Using Non Steroidal Anti Inflammatory Drugs and Physical Therapy


Affiliations
1 Department of Physiotherapy, College of Medicine (UCH) University of Ibadan, PMB 5017 GPO Dugbe Ibadan 2000001 Ibadan, Nigeria
2 Department of Physiotherapy, College of Medicine, University of Ibadan, Nigeria
3 Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Nigeria
     

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Objective

Non steroidal anti-inflammatory drugs (NSAIDs) are commonly used in managing osteoarthritis (OA). A patient with OA may have a coexisting hypertension for which antihypertensive drugs are prescribed. However evidence indicates that NSAIDs diminish efficacy of antihypertensive drugs.

Aim

The aim was to determine the respective and combined effects of NSAIDs and physical therapy in management of pain and reduced functional limitation among patients with concurrent hypertension and knee osteoarthritis (CHKO).

Design

This is a quasi-experimental study technique

Location

Physiotherapy and Medical Outpatient units of a tertiary facility.

Methods

Twenty-nine individuals (mean age = 65.71±9.96 years) with CHKO were purposively sampled and assigned to one of three treatment groups viz. Physiotherapy and NSAIDS (Group A); Physiotherapy Only (Group B); and NSAIDs only (Group C). All were on antihypertensive drugs during the study period. Resting systolic and diastolic blood pressure, pain rating and functional limitation were assessed using sphygmomanometer, verbal rating scale and the Osteoarthritis Index of Lequesne respectively.

Results

There was no significant difference in the pain and functional performance across the three groups (p>0.05). There was significant reduction in pain and increase in functional ability of the patients within each of the groups (p<0.05), with greatest within-group difference observed in Group C. The NSAID did not cause a significant difference in blood pressure of all the patients.

Conclusion

The outcome showed that either Physiotherapy or NSAID could bring about the relief of pain and functional improvement in patients with CHKO.

Clinical Rehabilitation Impact

Use of physiotherapy should be considered in managing symptoms of OA in patients with CHKO especially where drugdrug interaction is envisaged.


Keywords

Osteoarthritis; Hypertension; Physiotherapy; Antiinflammatory
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  • Management of Patients With Concurrent Hypertension and Osteoarthritis of the Knee: Comparative Effect of Using Non Steroidal Anti Inflammatory Drugs and Physical Therapy

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Authors

Talhatu K. Hamzat
Department of Physiotherapy, College of Medicine (UCH) University of Ibadan, PMB 5017 GPO Dugbe Ibadan 2000001 Ibadan, Nigeria
Adeolu O. Ajala
Department of Physiotherapy, College of Medicine, University of Ibadan, Nigeria
Fatai A. Fehintola
Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Nigeria

Abstract


Objective

Non steroidal anti-inflammatory drugs (NSAIDs) are commonly used in managing osteoarthritis (OA). A patient with OA may have a coexisting hypertension for which antihypertensive drugs are prescribed. However evidence indicates that NSAIDs diminish efficacy of antihypertensive drugs.

Aim

The aim was to determine the respective and combined effects of NSAIDs and physical therapy in management of pain and reduced functional limitation among patients with concurrent hypertension and knee osteoarthritis (CHKO).

Design

This is a quasi-experimental study technique

Location

Physiotherapy and Medical Outpatient units of a tertiary facility.

Methods

Twenty-nine individuals (mean age = 65.71±9.96 years) with CHKO were purposively sampled and assigned to one of three treatment groups viz. Physiotherapy and NSAIDS (Group A); Physiotherapy Only (Group B); and NSAIDs only (Group C). All were on antihypertensive drugs during the study period. Resting systolic and diastolic blood pressure, pain rating and functional limitation were assessed using sphygmomanometer, verbal rating scale and the Osteoarthritis Index of Lequesne respectively.

Results

There was no significant difference in the pain and functional performance across the three groups (p>0.05). There was significant reduction in pain and increase in functional ability of the patients within each of the groups (p<0.05), with greatest within-group difference observed in Group C. The NSAID did not cause a significant difference in blood pressure of all the patients.

Conclusion

The outcome showed that either Physiotherapy or NSAID could bring about the relief of pain and functional improvement in patients with CHKO.

Clinical Rehabilitation Impact

Use of physiotherapy should be considered in managing symptoms of OA in patients with CHKO especially where drugdrug interaction is envisaged.


Keywords


Osteoarthritis; Hypertension; Physiotherapy; Antiinflammatory