Synthesis, Characterization and Antimicrobial Activity of Cu(II),Co(II), Ni(II) and Zn(II),Complexes with O-N Donor Ligand

The complexes of the type MLXn, where M= Cu(II), Co(II), Ni(II), Zn(II) and X= H2O/Cl and L is the schiff base ligand prepared from 2,4-dihydroxy-5-Acetylacetophenone and 1,4-diaminobutane have been synthesized. All complexes isolated in solid, are stable in air and characterized by the elemental analysis, metal content determination, magnetic measurements, thermo gravimetric analysis (TGA), IR, and electronic spectral data. The physicochemical data suggest a pseudo octahedral structure to Cu(II) and an octahedral for Co(II), Ni(II), and Zn(II) complexes. The ligand field parameters have been calculated and related to the electronic environment. The Schiff base and its complexes were screened for their antimicrobial activities against various bacteria and fungi.