Indian Journal of Science and Technology

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This study is conducted to study distribution of DHEAs value and IGFBP3 value of children with precocious puberty in comparison with normal children and analyze correlation of their influence in precocious puberty. Study subjects were children who had visited pediatrics department of a University hospital from Jan. 2011, to Dec. 2011. Total count of the subjects was 94, with 45 male and 49 female. 54 were subjects with precocious puberty and the other 40, normal. Furthermore, gathered data were analyzed in frequency, T-test, ANOVA, and correlation test, using SPSS 19.0. In correlation analysis of DHEAs and IGFBP3 value in child with precocious puberty, correlation value of DHEAs was .442 and IGFBP-3, .464 (p < .01). Correlation coefficients were distributed comparatively low. In conclusion, when diagnosing precocious puberty, tests on sexual hormones and pituitary hormones such as LH, FSH, and ACTH besides DHEA-S and IGFBP3 tests should be performed and as such study has a small group of subjects, it should be further expanded with more cases as subjects.

Keywords

Children, Dehydroepiandrosterone, Luteinizing Hormone, Precocious Puberty
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