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The Antibacterial Activity of Acalypha indica L.


Affiliations
1 Department of Plant Biology & Plant Biotechnology, S.D.N.B. Vaishnav College for Women, Chrompet, Chennai–600 044, India
2 Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai–600 025, India
 

The antibacterial activity of Acalypha indica was investigated against three strains of human pathogenic bacteria viz., Bacillus subtilis, Staphylococcus aureus and Klebsiella pneumoniae using ethylacetate, hexane and methanol extracts of leaves, stem and ischolar_mains of Acalypha indica. The ethylacetate extracts of leaves and ischolar_mains inhibited the growth of all the three selected bacterial species. The in vitro assay may open way for complementary future investigations in identifying potentially useful properties of chemical and pharmacological importance.

Keywords

Acalypha indica, Antimicrobial Activity, Human Pathogenic Bacteria, Medicinal Plant
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  • Baron EJ, Peterson LR and Finegold SM (1994) Baily & Scott's Diagnostic Microbiology. 9th ed. Mosby-Year book, Inc., St. Louis.

  • Bauer AW, Kirby WM and Sherris JC (1966) Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 45, 493-496.

  • Ekwenye UN and Elegalam NN (2005) Antibacterial activity of ginger (Zingiber officinale Roscoe) and garlic (Allium sativum L.) extracts on Escherichia coli and Salmonella typhi. J. Mol. Med. Adv. Sci. 1, 411-416.

  • Fabricant DS and Farnsworth NR (2001) The value of plants used in traditional medicine for drug discovery. Environ. Health Per. Suppl. 109, 69–75.

  • Gangadevi V, Sethumeenal S, Yogeswari S and Rani G (2008) Screening endophytic fungi isolated from a medicinal plant, Acalypha indica L. for antibacterial activity. Indian J. Sci. Technol. 1(5), 1-6.

  • Gopalakrishnan V, Rao KNV, Loganathan V, Shanmuganathan S, Bollu VK and Sharma TB (2000) Antimicrobial activity of extracts of Acalypha indica Linn. Ind. J. Pharm. Co. 62, 347-350.

  • Jensen G, Wandall DA and Gaarsler K (1996) Antibiotic resistance in Shigella and Salmonella in rigion of Lithunia. Eur. J. Clin. Microbiol. Infect. Dis. 15, 872-886.

  • Lennette, EH, Balows A, Hausler WJ and Shadomy HJ (1985) Manual of Clinical Microbiology. 4 th ed. Amer. Soc. Microbiol., Washington.

  • Neu HC (1992) The crisis of antibiotic resistance. Science. 257, 1061-1069.

  • Niekel LG (1993) Antimicrobial activity of vascular plants. Econ. Bot. 13, 225.

  • Osler W (1983) Chemotherapy. In: Thomas CG. Medical Microbiology. 5th ed. Baillier Tindall, London, pp. 192.

  • Patel SJ, Nithin V and Pradeep S (2007) Screening for antimicrobial activity of weeds. The Internet J. Microbiol. 4(1), 1-7.

  • Reminton S (1991) Pharmaceutical Sciences. 17th ed. Mack Publishing Co., Eastan,

  • Samsam SH and Moatar F (1991) Natural medicines and plants. Mashal Publications, Tehran pp.123-130.

  • Serrentino J (1991) How Natural Remedies Work. Point Robert, WA: Harley and Marks Publishers, pp: 20 -22.

  • Shafiei A and Ghanbarpour A (1992) Fundamentals of antibiotics (translation), University of Tehran Publications, Tehran pp:5- 6.

  • Shah PM (2005) The need for new therapeutic agents: what is in the pipeline? Clinical Microbiol. Infection.11, 36–42. doi: 10.1111/j.1469-0691.2005.01141.x.

  • Solomon R, Kallidass, Subramaniam, Vimalan and Jayaraj (2005) Isolation, Identification and Study of Antimicrobial Property of a Bioactive Compound in an Indian Medicinal Plant Acalypha indica (Indian-Nettle). W. J. Microbiol. Biotech. 21, 1231-1236.

  • Suresh Reddy J, Rajeswara Rao P and Reddy MS (2002) Wound healing effects of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica in rats. J. Ethnopharmacol. 79, 249- 251.

  • WHO, IUCN, WWF (1993) Guidelines on the conservation of medicinal plants. p:1.

  • Yurdakok K, Sahin N and Ozmert E (1997) Shigella gasteroenteritis. Acta Paediatr. Jpn. 39, 681-683.


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  • The Antibacterial Activity of Acalypha indica L.

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Authors

V. Gangadevi
Department of Plant Biology & Plant Biotechnology, S.D.N.B. Vaishnav College for Women, Chrompet, Chennai–600 044, India
S. Yogeswari
Department of Plant Biology & Plant Biotechnology, S.D.N.B. Vaishnav College for Women, Chrompet, Chennai–600 044, India
S. Kamalraj
Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai–600 025, India
G. Rani
Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai–600 025, India
J. Muthumary
Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai–600 025, India

Abstract


The antibacterial activity of Acalypha indica was investigated against three strains of human pathogenic bacteria viz., Bacillus subtilis, Staphylococcus aureus and Klebsiella pneumoniae using ethylacetate, hexane and methanol extracts of leaves, stem and ischolar_mains of Acalypha indica. The ethylacetate extracts of leaves and ischolar_mains inhibited the growth of all the three selected bacterial species. The in vitro assay may open way for complementary future investigations in identifying potentially useful properties of chemical and pharmacological importance.

Keywords


Acalypha indica, Antimicrobial Activity, Human Pathogenic Bacteria, Medicinal Plant

References





DOI: https://doi.org/10.17485/ijst%2F2008%2Fv1i6%2F29582