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Phytochemical Analysis and Anti-diabetic Activity of Cadaba Fruticosa R.Br.


Affiliations
1 Sathyabama University, Chennai-119, India
2 Department of Pharmaceutical Sciences, Madras Medical College, Chennai-3, India
3 Jaya College of Engineering, Thiruninravur, Chennai-602024, India
 

Alcohol and aqueous extract of Cadaba fruticosa (leaves) were subjected for hypoglycemic activity in wistar rats (160-200 g). The oral administration of leaf extracts at dose 1000 mg/kg led to a significant blood glucose reduction. Phytochemical analysis of alcohol extract revealed the presence of terpenoids, flavanoids, steroids, proteins, alkaloids, gums, sugars and saponins but negative result was observed in aqueous extract except terpenoids, flavonaids, proteins, furans, gums and sugars. This study brings out the evidence regarding pharmacological and phytochemical activities of C. fruticosa.

Keywords

Acute Toxicity, Anti-diabetic, Alloxaninduced Diabetes, Cadaba Fruticosa
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  • Phytochemical Analysis and Anti-diabetic Activity of Cadaba Fruticosa R.Br.

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Authors

S. Arokiyaraj
Sathyabama University, Chennai-119, India
R. Radha
Department of Pharmaceutical Sciences, Madras Medical College, Chennai-3, India
S. Martin
Jaya College of Engineering, Thiruninravur, Chennai-602024, India
K. Perinbam
Sathyabama University, Chennai-119, India

Abstract


Alcohol and aqueous extract of Cadaba fruticosa (leaves) were subjected for hypoglycemic activity in wistar rats (160-200 g). The oral administration of leaf extracts at dose 1000 mg/kg led to a significant blood glucose reduction. Phytochemical analysis of alcohol extract revealed the presence of terpenoids, flavanoids, steroids, proteins, alkaloids, gums, sugars and saponins but negative result was observed in aqueous extract except terpenoids, flavonaids, proteins, furans, gums and sugars. This study brings out the evidence regarding pharmacological and phytochemical activities of C. fruticosa.

Keywords


Acute Toxicity, Anti-diabetic, Alloxaninduced Diabetes, Cadaba Fruticosa

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DOI: https://doi.org/10.17485/ijst%2F2008%2Fv1i6%2F29584