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Phytochemistry and Hemostatic Properties of some Medicinal Plants Sold as Anti-hemorrhagic in Cotonou Markets (Benin)


Affiliations
1 Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
2 Faculty of Science and Technology, Department of Animal Physiology, Laboratory of Pharmacology, University of Abomey-Calavi, 01 BP 526 Cotonou, Benin
3 Interfaculty Center of Formation and Research in Environment for the Sustainable Development, Laboratory of Toxicology and Environmental Health, University of Abomey-Calavi, 01 BP 1463 Cotonou, Benin
4 Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
5 Benin Center of Scientific and Technical Research, Pharmacognosy Laboratory of Essential Oils, Porto-Novo, Benin
 

Annona senegalensis (Leaves), Newbouldia laevis (Leaves), Cassytha filiformis (aerial part), Cissampelos mucronata (aerial part) are four species of medicinal plants commonly sold by herbalists in South Benin for treatment of bleeding. Hemostatic tests performed in vitro on hydro alcoholic extracts of these plants revealed that all of them have coagulant properties, with a percentage reduction of plasma re-calcification time which is 31% for C. filiformis and 39% for A. senegalensis. The action of these plant extracts is different from that of the classical pathway of blood coagulation. A. senegalensis extract also showed an astringent power. The phytochemical study of these plants revealed that: C. mucronata contains alkaloids and tannins; A. senegalensis contains tannins, mucilages and reducing compounds; C. filiformis contains alkaloids, tannins (gallic tannins and cathetics) and mucilage; N. leavis contains tannins, triterpenoids, mucilages and reducing compounds. The traditional use of plants as hemostatic is convicted with these results.

Keywords

Astringent, Hemostatic Tests, Herbal, Medicinal Plants
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  • Phytochemistry and Hemostatic Properties of some Medicinal Plants Sold as Anti-hemorrhagic in Cotonou Markets (Benin)

Abstract Views: 625  |  PDF Views: 130

Authors

C. Dandjesso
Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
J. R. Klotoa
Faculty of Science and Technology, Department of Animal Physiology, Laboratory of Pharmacology, University of Abomey-Calavi, 01 BP 526 Cotonou, Benin
T. V. Dougnon
Interfaculty Center of Formation and Research in Environment for the Sustainable Development, Laboratory of Toxicology and Environmental Health, University of Abomey-Calavi, 01 BP 1463 Cotonou, Benin
J. Segbo
Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
J-M. Ategbo
Faculty of Science and Technology, Department of Animal Physiology, Laboratory of Pharmacology, University of Abomey-Calavi, 01 BP 526 Cotonou, Benin
F. Gbaguidi
Benin Center of Scientific and Technical Research, Pharmacognosy Laboratory of Essential Oils, Porto-Novo, Benin
L. Fah
Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
B. Fanou
Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
F. Loko
Polytechnic School of Abomey-Calavi, Department of Human Biology, Research Laboratory of Applied Biology, University of Abomey-Calavi, 01 BP 2009 Cotonou, Benin
K. Dramane
Faculty of Science and Technology, Department of Animal Physiology, Laboratory of Pharmacology, University of Abomey-Calavi, 01 BP 526 Cotonou, Benin

Abstract


Annona senegalensis (Leaves), Newbouldia laevis (Leaves), Cassytha filiformis (aerial part), Cissampelos mucronata (aerial part) are four species of medicinal plants commonly sold by herbalists in South Benin for treatment of bleeding. Hemostatic tests performed in vitro on hydro alcoholic extracts of these plants revealed that all of them have coagulant properties, with a percentage reduction of plasma re-calcification time which is 31% for C. filiformis and 39% for A. senegalensis. The action of these plant extracts is different from that of the classical pathway of blood coagulation. A. senegalensis extract also showed an astringent power. The phytochemical study of these plants revealed that: C. mucronata contains alkaloids and tannins; A. senegalensis contains tannins, mucilages and reducing compounds; C. filiformis contains alkaloids, tannins (gallic tannins and cathetics) and mucilage; N. leavis contains tannins, triterpenoids, mucilages and reducing compounds. The traditional use of plants as hemostatic is convicted with these results.

Keywords


Astringent, Hemostatic Tests, Herbal, Medicinal Plants

References





DOI: https://doi.org/10.17485/ijst%2F2012%2Fv5i8%2F30522