Critical Scrutiny of the Visualization and Detection of Oral Potentially Malignant Disorders by Chemiluminescent Illumination

The aim of this study was to critically analyse the effectiveness of Vizilite in detecting Oral Potentially Malignant Disorders (OPMD). This study was conducted on 70 patients, among them, 50 were identified to have Oral Potentially Malignant Disorders and the remaining 20 subjects had no apparent lesions. Complete oral examination was performed for all the patients with normal incandescent light and Vizilite. All 50 cases with oral lesions underwent incision biopsy. The sensitivity and specificity of vizilite was investigated. Vizilite examination was 100% sensitive and specific for leukoplakia. But, the examination was not quite sensitive for lichen planus and oral submucous fibrosis. No additional lesions were detected in normal subjects, no extra focal areas of lesions were detected in OPMD patients and there was no change in the biopsy site after vizilite examination. Oral Medicine specialists can diagnose the presence or can predict the progress of any Oral Potentially Malignant Disorders by conventional screening and complete examination. No additional benefits were obtained from the use of Vizilite.