International Journal of Physiology

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A Study of Nerve Conduction Test & Other Hematological Parameters in Diabetics


Affiliations
1 Department of Physiology, Banas Medical College & Research Institute, Palanpur, Gujarat, India
2 Department of Physiology, Gujarat Adani Institute Of Medical Science, Bhuj, Gujarat, India
     

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Background: Nerve conduction studies (NCS) are most sensitive, reliable and non-invasive investigation to detect diabetic neuropathy. Sensory nerves are more affected as compared to motor nerves in diabetic neuropathy. Understanding the Nerve conduction studies is useful for early detection polyneuropathy and prevention of its dreaded complications.

Materials and Method: The present study was conducted among 30 subjects of type 2 Diabetic and 30 non diabetics subjects. Haematological parameters such as HbA1c, platelet count, prothrombin time, APTT, triglycerides, LDL and HDL levels were estimated. Motor nerve conduction velocity median , ulnar, common peroneal and posterior tibial nerve and sensory nerve conduction velocity median , ulnar and sural nerve were recorded.

Result: Mean age of diabetic patients was 51±.4.8 year. Most of the subjects (86.7%) were male. Sensory nerve conduction of sural nerve was signiicantly reduced in diabetic patients as compared to non diabetic patients. SNCV of sural nerve showed deterioration with the duration of diabetes, poor glycemic control and patients with altered lipid profile.

Conclusion: Nerve conduction velocity testing of sural nerve is useful for early detection of diabetic neuropathy and reduce the burden of complication and to improve the quality of life in diabetics.


Keywords

Sensory Nerve Conduction Velocity, Sural Nerve, Diabetic Peripheral Neuropathy, HbA1c.
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  • A Study of Nerve Conduction Test & Other Hematological Parameters in Diabetics

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Authors

Jasmin J. Parmar
Department of Physiology, Banas Medical College & Research Institute, Palanpur, Gujarat, India
Jitendra R. Patel
Department of Physiology, Gujarat Adani Institute Of Medical Science, Bhuj, Gujarat, India

Abstract


Background: Nerve conduction studies (NCS) are most sensitive, reliable and non-invasive investigation to detect diabetic neuropathy. Sensory nerves are more affected as compared to motor nerves in diabetic neuropathy. Understanding the Nerve conduction studies is useful for early detection polyneuropathy and prevention of its dreaded complications.

Materials and Method: The present study was conducted among 30 subjects of type 2 Diabetic and 30 non diabetics subjects. Haematological parameters such as HbA1c, platelet count, prothrombin time, APTT, triglycerides, LDL and HDL levels were estimated. Motor nerve conduction velocity median , ulnar, common peroneal and posterior tibial nerve and sensory nerve conduction velocity median , ulnar and sural nerve were recorded.

Result: Mean age of diabetic patients was 51±.4.8 year. Most of the subjects (86.7%) were male. Sensory nerve conduction of sural nerve was signiicantly reduced in diabetic patients as compared to non diabetic patients. SNCV of sural nerve showed deterioration with the duration of diabetes, poor glycemic control and patients with altered lipid profile.

Conclusion: Nerve conduction velocity testing of sural nerve is useful for early detection of diabetic neuropathy and reduce the burden of complication and to improve the quality of life in diabetics.


Keywords


Sensory Nerve Conduction Velocity, Sural Nerve, Diabetic Peripheral Neuropathy, HbA1c.

References