International Journal of Physiology

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Evaluation of Differential Levels of Serum Interleukin-6 in Pre-Eclamptic and Normal Pregnancy Women


Affiliations
1 Hind Institute of Medical Sciences, Safedabad, Barabanki, India
2 Dr.Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomti Nagar, Lucknow, India
     

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There has been an increase incidence of Pre eclampsia which is one of the important causes of maternal as well as foetal mortality and morbidity. The changing life style and various stresses in this fast growing world further increase the incidence of Pre eclampsia. The exact cause is still not known beside exploratory study but it seems a state of inflammatory and oxidative stress. Our aim was to evaluate the role of Interleukin 6 (IL6) and to compare its value in normal pregnancy and pre eclampsia. We found in this study that level of IL6 is significantly high in pre-eclamptic compare to normal pregnant women. Our study shows that Preeclampsia pregnancy is associated with an enhanced maternal inflammatory condition.

Keywords

Pre Eclampsia, Interleukin-6, Inflammatory, Oxidative Stress, Mortality, Pregnancy.
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  • Evaluation of Differential Levels of Serum Interleukin-6 in Pre-Eclamptic and Normal Pregnancy Women

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Authors

Mohd. Nawaz
Hind Institute of Medical Sciences, Safedabad, Barabanki, India
Manish Kumar Verma
Dr.Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand, Gomti Nagar, Lucknow, India

Abstract


There has been an increase incidence of Pre eclampsia which is one of the important causes of maternal as well as foetal mortality and morbidity. The changing life style and various stresses in this fast growing world further increase the incidence of Pre eclampsia. The exact cause is still not known beside exploratory study but it seems a state of inflammatory and oxidative stress. Our aim was to evaluate the role of Interleukin 6 (IL6) and to compare its value in normal pregnancy and pre eclampsia. We found in this study that level of IL6 is significantly high in pre-eclamptic compare to normal pregnant women. Our study shows that Preeclampsia pregnancy is associated with an enhanced maternal inflammatory condition.

Keywords


Pre Eclampsia, Interleukin-6, Inflammatory, Oxidative Stress, Mortality, Pregnancy.

References