International Journal of Physiology

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Eosinophil Count in High Altitude Natives of Nepal


Affiliations
1 Prof & Head, Dept of Physiology, Haldia Institute of Dental Sciences and Research, Banbishnupur, West Bengal
     

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Normally eosinophil constitutes 1-7% with it's absolute count < 700 cells /dl of blood but while studying the Differential Leukocyte Count (DLC) of the medical students it is found that the percentage of eosinophils in DLC is much higher among a significant number of Nepalese students of hill region though they have no complains of any diseases. The present study is therefore undertaken to study whether the eosinophil count of normal high altitude natives is significantly higher than the normal low landers or not. Keeping this in view the MBBS students of Nepali and Indian origin are randomly selected and the Differential Leukocyte (Eosinophil) Count (DEC) and Absolute Eosinophil Count (AEC) are done by the standard hematological techniques along with the ESR value of individual subjects. It was found that the normal range of DEC is significantly high in Nepali students of high altitude natives along with the AEC than that of low landers . Therefore it can be opined that the normal range of eosinophil count among the high altitude natives may be higher than the standard reference value which might be physiological as suggested by their normal ESR values.

Keywords

Eosinophilia, Eosinophil Count, High Altitude Natives
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  • William FK(2002). Disorders of leukocyte function and number. In: PDQ Hematology, ed., B C Decker Inc., Hamilton, Canada.163-193.

  • Emerson SG(2000). Approach to the patients with leukocytes. In: Kelley’s Text Book of Internal medicine ed. H D Homes, 4th Ed, Lippincott Williams & Wilkins,1600-1648.

  • Todd WTA, Lockwood DNJ, Sundar S(2007). Infectous disease, In: Davidson’s Principles & practice of medicine. Ed. Boon A N, Colleridge NR, walkes BR, Hunter JAA, 20th ed, Churchill Livingstone, 283-373.

  • Nutman TB (2007). Evaluation and differential diagnosis of marked, persistent eosinophilia, , Immunol Allergy clin North Am, 27(3): 529-549.

  • Holland SM, Gallin JI (2005). Disorders of Granulocytes and Monocytes, In: Harrisons Principles of internal Medicine,16th Ed, Ed Kasper DL Fanci SA , Lengo DL etc, McGraw Hill. 349-357.

  • Rothenberg ME(1998). Eosinophilia. N Eng J Med 338: 1592-1612.

  • Panda BN, Raha B , Bhalla JS and Jayaswal R, (1992). Short term treatment of tropical eosiniphilia with diethylcarbamazine: Impact on clinical, hematological and spirometric data, Ind J Tub 39:117-122.

  • Ghai CL (2007). In : Text Book of practical Physiology, Jaypee Broth.Med., Pub(P) Ltd, New Delhi, 90-93.

  • Indrayan A and Sarmukaddam SB, In: Medical Biostatistics, Marcell Dekker Inc. pub., New York, 2001, p-405

  • Marshall SE (2007). Immunological factors in disease. In.: Davidson’s Principles & practice of medicine. Ed. Boon A N, Colledge NR, Walkes BR, Hunter JAA, 20th ed, Churchill Livingstone, Edinburgh,77-78.

  • Weller PF (1992). Eosinophilia in traveler. Med Clin North Am76: 1413-1417.

  • Kim YJ, Nutman B (2006), Eosinophilia :Causes and pathobiology in persons with prior exposure in tropical areas with an emphasis in parasitic infections. Curr Infec Dis Rep, 8:43-58.

  • Stephan E and Burchard GD(2008), Eosinophilia in returning travellers . Dtsch Arztebl Int 105(46):801-807.

  • Lawrence JH, Rex LH, William S, Washerman LR and Hennesy TG,(1952), A physiological study in the Peruvian Andes . Acta Medica Scandinavica 142(2): 117-131.


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  • Eosinophil Count in High Altitude Natives of Nepal

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Authors

Asim Kumar Basak
Prof & Head, Dept of Physiology, Haldia Institute of Dental Sciences and Research, Banbishnupur, West Bengal

Abstract


Normally eosinophil constitutes 1-7% with it's absolute count < 700 cells /dl of blood but while studying the Differential Leukocyte Count (DLC) of the medical students it is found that the percentage of eosinophils in DLC is much higher among a significant number of Nepalese students of hill region though they have no complains of any diseases. The present study is therefore undertaken to study whether the eosinophil count of normal high altitude natives is significantly higher than the normal low landers or not. Keeping this in view the MBBS students of Nepali and Indian origin are randomly selected and the Differential Leukocyte (Eosinophil) Count (DEC) and Absolute Eosinophil Count (AEC) are done by the standard hematological techniques along with the ESR value of individual subjects. It was found that the normal range of DEC is significantly high in Nepali students of high altitude natives along with the AEC than that of low landers . Therefore it can be opined that the normal range of eosinophil count among the high altitude natives may be higher than the standard reference value which might be physiological as suggested by their normal ESR values.

Keywords


Eosinophilia, Eosinophil Count, High Altitude Natives

References