International Journal of Physiology

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Serum Total Estradiol Level is Associated with Waist Circumference in Adult Males


Affiliations
1 Junior Resident, Department of Physiology
2 Professor and Head, Department of Physiology, G.S.V.M. Medical College, Kanpur, U.P., India
3 Asstt. Professor, Department of Physiology, AIIMS, Rishikesh, U.P, India
4 Department of Community Medicine, GSVM Medical College, Kanpur, U.P.
     

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Obesity is becoming pandemic and in developing country like India problem of obesity is also growing at a very fast rate. In men Estradiol (E2) is important must be kept in balance for good health. Serum estradiol changes with Body weight. This study was conducted to see the association of serum total estradiol (E2) level with the waist circumference in adult males. It was a cross sectional study, conducted on 89 adult males (aged 18-50 years). Anthropometric measurement i.e. waist circumference (cm) was taken as a criteria for classifying normal weight and overweight&amp;obese males. The morning venous blood sample was drawn between 8-11 A.M. from each subject and serum was separated. Serum Total estradiol was measured using ELISA. When compared with waist circumference, serum total estradiol in normal weight "Group A" with W.C. < 90cm, was 19.61±8.56pg/ml and in overweight and obese subjects, "Group B" with W.C. > 90cm it was 52.10±29.83 pg/ml. Thus it was concluded that Serum Total Estradiol level significantly increased in "Group B" (W.C. > 90cm) as compared to subjects with" Group A" (W.C.< 90cm).Therefore we can delineate that serum total estradiol might increase significantly because of increased abdominal fat mass in overweight and obese subjects i.e. subjects who had increased waist circumference(> 90 cm)

Keywords

Obesity, (W.C.) Waist Circumference (cm), Serum Estradiol (E2)
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  • Clegg DJ, Benoit SC, Barrera JG and Woods SC. Estrogen Mediates Body Fat Distribution and Brain Sensitivity to Adiposity Signals. Diabetes. 2003; 52 (supplement1).

  • Clegg DJ, Brown LM, Woods SC and Benoit SC. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes. 2006; 55: 978-987.

  • Vandenput L, Mellstrom D , Karlsson MK, Orwoll E, Labrie F , Ljunggren O , Ohlsson C . Serum estradiol is associated with lean mass in elderly Swedish men. Eur J Endocrinol. April 2010; 162(4): 737-45. Epub 2010 Jan 8.

  • Muller M, den Tonkelaar I, ThijssenJH, Grobbee DE and van der Schouw YT. Endogenous sex hormones in men aged 40-80 years. European Journal of Endocrinology 2003; 149: 583-589.

  • Visscher TL, Seidell JC, Molarius A , van der Kuip D, Hofman A , Witteman JC. A comparison of body mass index, waist-hip ratio and waist circumference as predictors of all-cause mortality among the elderly: the Rotterdam study. Int J Obes Relat Metab Disord. Nov 2001; 25(11): 1730-5.

  • Vermeulen A, Kaufman JM , Goemaere S, van Pottelberg I. Estradiol in elderly men. Aging Male. Jun 2002; 5: (2) 98-102.


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  • Serum Total Estradiol Level is Associated with Waist Circumference in Adult Males

Abstract Views: 376  |  PDF Views: 0

Authors

Enam Ahmad
Junior Resident, Department of Physiology
Jalaj Saxena
Professor and Head, Department of Physiology, G.S.V.M. Medical College, Kanpur, U.P., India
Arun Goel
Asstt. Professor, Department of Physiology, AIIMS, Rishikesh, U.P, India
Dolly Rastogi
Department of Community Medicine, GSVM Medical College, Kanpur, U.P.
Saurabh Saha
Department of Community Medicine, GSVM Medical College, Kanpur, U.P.
Chitra Srivastava
Department of Community Medicine, GSVM Medical College, Kanpur, U.P.
Mohd. Hifzur Rehman
Department of Community Medicine, GSVM Medical College, Kanpur, U.P.
D S Martolia
Department of Community Medicine, GSVM Medical College, Kanpur, U.P.

Abstract


Obesity is becoming pandemic and in developing country like India problem of obesity is also growing at a very fast rate. In men Estradiol (E2) is important must be kept in balance for good health. Serum estradiol changes with Body weight. This study was conducted to see the association of serum total estradiol (E2) level with the waist circumference in adult males. It was a cross sectional study, conducted on 89 adult males (aged 18-50 years). Anthropometric measurement i.e. waist circumference (cm) was taken as a criteria for classifying normal weight and overweight&amp;obese males. The morning venous blood sample was drawn between 8-11 A.M. from each subject and serum was separated. Serum Total estradiol was measured using ELISA. When compared with waist circumference, serum total estradiol in normal weight "Group A" with W.C. < 90cm, was 19.61±8.56pg/ml and in overweight and obese subjects, "Group B" with W.C. > 90cm it was 52.10±29.83 pg/ml. Thus it was concluded that Serum Total Estradiol level significantly increased in "Group B" (W.C. > 90cm) as compared to subjects with" Group A" (W.C.< 90cm).Therefore we can delineate that serum total estradiol might increase significantly because of increased abdominal fat mass in overweight and obese subjects i.e. subjects who had increased waist circumference(> 90 cm)

Keywords


Obesity, (W.C.) Waist Circumference (cm), Serum Estradiol (E2)

References