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Diagnostic Approach to Bleeding and Clotting Disorders - Review
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Bleeding is one of the most serious and significant of the cardinal manifestations of disease. It may occur from a local site or may be generalized. Bleeding associated with a local lesion may be superimposed on either a normal or a defective haemostatic mechanism. In contrast general bleeding is usually associated with a hemorrhagic diathesis. This article covers various investigations and protocol to accurately diagnose the defect in the hemostasis mechanism.
Keywords
Bleeding Disorder, Clotting Disorder, Hemophilia, Thrombocytopenia
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- Colman RW et al: Overview of hemostasis, in Hemostasis and Thrombosis, 5th ed, RW Colman et al (eds). Philadelphia, Lippincott Williams & Wilkins, 2006, pp 3-16
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