Indian Journal of Chemical Technology

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Highly substituted pyrazoles have been prepared by condensing 1,3-diketones and various hydrazine derivatives using silica-phosphoric acid nanoparticles (nano-SPA). This nano solid catalyst has been prepared by the reaction of nano silica chloride with dry phosphoric acid. This green methodology has advantages such as short reaction times, simple work-up, high efficiency, reusability of the catalyst and no use of any solvents.

Keywords

Highly Substituted Pyrazoles, Heterogeneous, Nano Silica-Phosphoric Acid, Solid Acid Catalyst.
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