The complication and severity of disease can be reduced if the diagnosis and treatment can be made at early stage. This has led to search of tools called molecular biomarker, which help in early diagnosis of disease, predict future disease progression, and evaluate the response to therapy thus avoiding complications. Biomarkers are being used in both the field of medicine and dentistry for diagnosis, monitoring of therapy outcomes, and drug discovery. In the field of periodontics salivary and GCF biomarkers are being used for detection of active disease state, for monitoring the response to therapy or for measuring the degree of susceptibility to future disease progression. This review highlights about different characteristics of biomarkers and their role in periodontal disease.
Keywords
GCF, Saliva, Therapy Monitoring.
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