Journal of Pierre Fauchard Academy (India Section)

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Treatment Outcome with a Revascularization Protocol Using Double and Triple Antibiotic Pastes in Immature Necrotic Teeth – A Double Blinded Randomized Control Clinical Trial


Affiliations
1 Department of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, 603103, India
2 Department of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, India
3 Sri Venkateswara Dental College and Hospital, Chennai, India
4 Department of Pharmacology, Sri Venkateswara Dental College and Hospital, Chennai, India
     

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Aim: The aim of this clinical trial is to evaluate the regenerative potential of two antibiotic pastes in permanent teeth with necrotic pulp and open apex and compare it with a standard treatment using mineral trioxide aggregate.
Materials and methods: This interventional study was conducted to assess the revascularization potential. It was designed with two test arms and one control arm. LA was administered, access was established under rubber dam, irrigation was done, and each tooth received an antibiotic paste depending on the test arm to which it belonged. The control arm received a standard MTA apexification. Primary and secondary outcomes were assessed at baseline, 6 months and 12 months. Data were tabulated and analyzed.
Results: Though there was an increase in ischolar_main length in the test arms, the difference was not statistically significant among the various groups at the different time intervals of assessment. Overall, the mean pain scores decreased over the study period in all the three groups. Though no ischolar_main closure was found at baseline among the test groups, a statistically significant improvement in the ischolar_main closure scores was observed in Group A, when compared to Group B, at the end of 6th and 12th month of intervention.
Conclusion: The results to this study show that the revascularization potential of triple antibiotic paste is superior to that of the double antibiotic group. The increase in the ischolar_main length is statistically superior over the study period in the triple antibiotic arm when compared to that of the double antibiotic arm.

Keywords

Double Antibiotic Paste, Regenerative Endodontics, Revasculasrisation Protocol, Triple Antibiotic Paste.
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  • Treatment Outcome with a Revascularization Protocol Using Double and Triple Antibiotic Pastes in Immature Necrotic Teeth – A Double Blinded Randomized Control Clinical Trial

Abstract Views: 191  |  PDF Views: 0

Authors

Saravanan Poorni
Department of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, 603103, India
Manali Ramakrishnan Srinivasan
Department of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, India
Dasrathan Duraivel
Department of Conservative Dentistry and Endodontics, Sri Venkateswara Dental College and Hospital, Chennai, India
Lodd Mahendra
Sri Venkateswara Dental College and Hospital, Chennai, India
S. Premkumari
Department of Pharmacology, Sri Venkateswara Dental College and Hospital, Chennai, India

Abstract


Aim: The aim of this clinical trial is to evaluate the regenerative potential of two antibiotic pastes in permanent teeth with necrotic pulp and open apex and compare it with a standard treatment using mineral trioxide aggregate.
Materials and methods: This interventional study was conducted to assess the revascularization potential. It was designed with two test arms and one control arm. LA was administered, access was established under rubber dam, irrigation was done, and each tooth received an antibiotic paste depending on the test arm to which it belonged. The control arm received a standard MTA apexification. Primary and secondary outcomes were assessed at baseline, 6 months and 12 months. Data were tabulated and analyzed.
Results: Though there was an increase in ischolar_main length in the test arms, the difference was not statistically significant among the various groups at the different time intervals of assessment. Overall, the mean pain scores decreased over the study period in all the three groups. Though no ischolar_main closure was found at baseline among the test groups, a statistically significant improvement in the ischolar_main closure scores was observed in Group A, when compared to Group B, at the end of 6th and 12th month of intervention.
Conclusion: The results to this study show that the revascularization potential of triple antibiotic paste is superior to that of the double antibiotic group. The increase in the ischolar_main length is statistically superior over the study period in the triple antibiotic arm when compared to that of the double antibiotic arm.

Keywords


Double Antibiotic Paste, Regenerative Endodontics, Revasculasrisation Protocol, Triple Antibiotic Paste.

References