Karnataka Anaesthesia Journal

The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off


Background and Aims: Bispectral index response(BIS) reflects cerebral cortical activity and is an important pharmacodynamic parameter of anaesthetic effects on central nervous system. The prospective double blinded controlled study was undertaken to study effect of beta- 1 antagonist esmolol on BIS, arm movement during intubation. Methods: Fifty adult patients aged 18 to 60 years scheduled for elective non-cardiac, non-cranial surgery surgery under general anaesthesia were undertaken for the study. Randomisation was done using closed envelope method. Data was analysed with Stat-View (Version 18, SPSS). Chi-square test was used to compare percentage of patients with arm movement. Results: Demographic variables age, weight, intubation duration, sex had P-value greater than 0.05. Arm movement was observed in 40% of patients in Esmolol group against 84% patients in Control group. T-value was below 0.05. Conclusion: Addition of esmolol leads to attenuation of haemodynamic, arm movements and BIS increase in response to intubation.

Keywords

Anesthetic depth, bispectral index, intubation
User
Notifications
Font Size