Karnataka Anaesthesia Journal

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Anaesthetic Management of a Paediatric Case of G6pd Deficiency Posted for Craniotomy


Affiliations
1 Department of Anaesthesiology, Father Muller Medical College, Mangalore – 575002, Karnataka, India
 

Glucose-6-Phosphate Dehydrogenase deficiency is an inherited X-linked enzymatic disorder that results in haemolytic anaemia whenever the body faces oxidative stress in circumstances such as drug interactions (including anaesthetic agents), infections and surgical stress. A complete pre-anaesthetic evaluation, thorough planning of anaesthetic technique and adequate monitoring helps avoid oxidative stress in the perioperative period. The authors report the successful management of a 9-month old with G6PD deficiency who underwent craniotomy with no acute or delayed complications of the condition.

Keywords

Glucose-6-Phosphate, Haemolysis, Neuroanaesthesia.
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  • Anaesthetic Management of a Paediatric Case of G6pd Deficiency Posted for Craniotomy

Abstract Views: 69  |  PDF Views: 48

Authors

Delma D. Cunha
Department of Anaesthesiology, Father Muller Medical College, Mangalore – 575002, Karnataka, India
P. S. Balakrishna Achar
Department of Anaesthesiology, Father Muller Medical College, Mangalore – 575002, Karnataka, India
Priya Mitali
Department of Anaesthesiology, Father Muller Medical College, Mangalore – 575002, Karnataka, India
Kishan Shetty
Department of Anaesthesiology, Father Muller Medical College, Mangalore – 575002, Karnataka, India

Abstract


Glucose-6-Phosphate Dehydrogenase deficiency is an inherited X-linked enzymatic disorder that results in haemolytic anaemia whenever the body faces oxidative stress in circumstances such as drug interactions (including anaesthetic agents), infections and surgical stress. A complete pre-anaesthetic evaluation, thorough planning of anaesthetic technique and adequate monitoring helps avoid oxidative stress in the perioperative period. The authors report the successful management of a 9-month old with G6PD deficiency who underwent craniotomy with no acute or delayed complications of the condition.

Keywords


Glucose-6-Phosphate, Haemolysis, Neuroanaesthesia.

References