Anaesthetic Management of a Paediatric Case of G6pd Deficiency Posted for Craniotomy

Glucose-6-Phosphate Dehydrogenase deficiency is an inherited X-linked enzymatic disorder that results in haemolytic anaemia whenever the body faces oxidative stress in circumstances such as drug interactions (including anaesthetic agents), infections and surgical stress. A complete pre-anaesthetic evaluation, thorough planning of anaesthetic technique and adequate monitoring helps avoid oxidative stress in the perioperative period. The authors report the successful management of a 9-month old with G6PD deficiency who underwent craniotomy with no acute or delayed complications of the condition.