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A Study on the Cause of Death Due to Burn Cases and Histopathological Changes in North Indian Setting-A Cross Sectional Study


Affiliations
1 Senior Resident, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, UP, India
2 Associate Professor, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, UP, India
3 Professor, King George’s Medical Universities, Lucknow, UP, India
4 Assistant Professor, King George’s Medical Universities, Lucknow, UP, India
5 Associate Professor, King George’s Medical Universities, Lucknow, UP, India
     

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Background: Fatal burns and related injuries are major cause of death and disability. There are certain pathological changes such as lungs shows necrotizing pneumonia, congestion of alveolar walls, capillary proliferation, intra alveolar oedema, giant epithelial cells Objective: To study on the cause of death due to burn cases and histopathological changes in north Indian setting. Method: This was a cross-sectional study. All autopsies with history of burn injury were studied to find out the significant histopathological change in lung. Cases was thoroughly studied using specially designed proforma that included demographic profile of deceased, history from relatives, police & hospital records, autopsy findings. Results: The most common cause of death due to burn injury was found to be Sepsis (48.2%) and neurogenic shock (29.5%). On histopathological examination, Congestion in trachea was present in majority 434 (78.9%) cases while Tracheal soot particles were present in only 40 (7.3%) cases. Specimens of 375 cases were available for histopathology out of which 52 (13.9%) specimens were autolyzed. Changes suggestive of Pneumonia (50.1%), Congestion (83.7%), alveolar and interstitial haemorrhage (63.2%) were present in majority of the cases while changes suggestive of alveolar interstitial edema (64.3%), alveolar wall disruption (66.1%), inflammatory cells (55.5%), hyaline membrane (79.7%) and Fibrin strands (79.7) were absent in majority of cases. Capillary dilatation was present in 39.2%. Conclusion: In the present study, an important observation in burn deaths is the Sepsis and Neurogenic shock. Congestion in trachea was most common on histopathological change.

Keywords

Fatal burns, Cause of death, Histopathological change
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  • A Study on the Cause of Death Due to Burn Cases and Histopathological Changes in North Indian Setting-A Cross Sectional Study

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Authors

Pradeep Kumar Yadav
Senior Resident, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, UP, India
Richa Choudhury
Associate Professor, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, UP, India
Anoop Kumar Verma
Professor, King George’s Medical Universities, Lucknow, UP, India
Mousami Singh
Assistant Professor, King George’s Medical Universities, Lucknow, UP, India
Raja Rupani
Associate Professor, King George’s Medical Universities, Lucknow, UP, India
Sangeeta Kumari
Assistant Professor, King George’s Medical Universities, Lucknow, UP, India
Rajiv Ratan Singh
Associate Professor, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, UP, India

Abstract


Background: Fatal burns and related injuries are major cause of death and disability. There are certain pathological changes such as lungs shows necrotizing pneumonia, congestion of alveolar walls, capillary proliferation, intra alveolar oedema, giant epithelial cells Objective: To study on the cause of death due to burn cases and histopathological changes in north Indian setting. Method: This was a cross-sectional study. All autopsies with history of burn injury were studied to find out the significant histopathological change in lung. Cases was thoroughly studied using specially designed proforma that included demographic profile of deceased, history from relatives, police & hospital records, autopsy findings. Results: The most common cause of death due to burn injury was found to be Sepsis (48.2%) and neurogenic shock (29.5%). On histopathological examination, Congestion in trachea was present in majority 434 (78.9%) cases while Tracheal soot particles were present in only 40 (7.3%) cases. Specimens of 375 cases were available for histopathology out of which 52 (13.9%) specimens were autolyzed. Changes suggestive of Pneumonia (50.1%), Congestion (83.7%), alveolar and interstitial haemorrhage (63.2%) were present in majority of the cases while changes suggestive of alveolar interstitial edema (64.3%), alveolar wall disruption (66.1%), inflammatory cells (55.5%), hyaline membrane (79.7%) and Fibrin strands (79.7) were absent in majority of cases. Capillary dilatation was present in 39.2%. Conclusion: In the present study, an important observation in burn deaths is the Sepsis and Neurogenic shock. Congestion in trachea was most common on histopathological change.

Keywords


Fatal burns, Cause of death, Histopathological change



DOI: https://doi.org/10.37506/v20%2Fi1%2F2020%2Fmlu%2F194292