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Investigating the Level of Vitamin E, C and Superoxide Dismutase in Patients with Allergic Asthma and Allergic Asthma with Helminths Infection


Affiliations
1 Dept. of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq
2 Branch of Clinical Laboratory Sciences, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq
3 Ministry of Health, Baghdad, Iraq
     

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The aim of this study was to investigate the relationship of antioxidant activity, vitamin E, vitamin C and superoxide dismutase with the severity of allergic asthma by estimating their level in the patients’ sera, as well as evaluating their association with the level of total and specific serum IgE in allergic asthmatics and allergic asthmatics with helminths infection. The study applied on 180 subjects divided into three groups, 100 patients with allergic asthma and 50 patients having allergic asthma with helminths infection. The group of patients included 50 males and 100 females age 15-60 years. The control group comprised of 30 healthy individuals, included 14 males and 16 females age range 16-60 years. For each participant, the medical history was considered; the total and specific IgE levels, vitamin E, vitamin C and superoxide dismutase levels were determined in the patient’s sera using ELISA technique. The present study has demonstrated an increased level in serum total IgE in the patients’ groups (allergic asthma group and allergic asthma with helminths) compare to the control group, mean 374.54 IU/mL; 472.24 IU/mL; 29.21 IU/mL respectively. The level differences among the three groups are highly significant when compared statistically.

Keywords

Allergic asthma, vitamin E, vitamin C, superoxide dismutase, antioxidant, asthma with helminths infection, total IgE, specific IgE
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  • Investigating the Level of Vitamin E, C and Superoxide Dismutase in Patients with Allergic Asthma and Allergic Asthma with Helminths Infection

Abstract Views: 390  |  PDF Views: 0

Authors

Narjis Abdul Rahman Oudah
Dept. of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq
Ahmed A. Mohammed
Branch of Clinical Laboratory Sciences, College of Pharmacy, Mustansiriyah University, Baghdad, Iraq
Kareem S. Chead Al-Teea
Ministry of Health, Baghdad, Iraq

Abstract


The aim of this study was to investigate the relationship of antioxidant activity, vitamin E, vitamin C and superoxide dismutase with the severity of allergic asthma by estimating their level in the patients’ sera, as well as evaluating their association with the level of total and specific serum IgE in allergic asthmatics and allergic asthmatics with helminths infection. The study applied on 180 subjects divided into three groups, 100 patients with allergic asthma and 50 patients having allergic asthma with helminths infection. The group of patients included 50 males and 100 females age 15-60 years. The control group comprised of 30 healthy individuals, included 14 males and 16 females age range 16-60 years. For each participant, the medical history was considered; the total and specific IgE levels, vitamin E, vitamin C and superoxide dismutase levels were determined in the patient’s sera using ELISA technique. The present study has demonstrated an increased level in serum total IgE in the patients’ groups (allergic asthma group and allergic asthma with helminths) compare to the control group, mean 374.54 IU/mL; 472.24 IU/mL; 29.21 IU/mL respectively. The level differences among the three groups are highly significant when compared statistically.

Keywords


Allergic asthma, vitamin E, vitamin C, superoxide dismutase, antioxidant, asthma with helminths infection, total IgE, specific IgE



DOI: https://doi.org/10.37506/v20%2Fi1%2F2020%2Fmlu%2F194428