Study Impact of Hyperuricemia on the Occurrence of Atrial Fibrillation in Patients Admitted to CCU in Al-Diwaniyah Teaching Hospital

Background: A possible direct link between SUA and AF has barely been addressed. Several studies have reported an association between SUA and AF. An increasing body of evidence suggests that SUA may represent a marker of AF risk. The association between SUA level and AF has been demonstrated. Moreover, Nyrnes A et al. found that serum uric acid levels in men are higher than in women throughout life, although SUA levels increase after menopause, and that baseline SUA was associated with an increased risk for future AF in both sexes. In addition, the occurrence of AF increases with age, and the fact that SUA levels in women, in contrast to men, increase with age may account for the higher risk estimates seen in women. Aim of the study: To evaluate the possible association between serum uric acid and atrial fibrillation in patients admitted to coronary care unit. Patients and Method: In this hospital based study, in order to explore the prevalence rate of hyperuricemia in patients with atrial fibrillation, the coronary care unit in Al-Diwaniyah teaching hospital was prospectively reviewed for newly admitted patients with atrial fibrillation during the period extending from April the 15th 2019 through July the 15 the 2019. Results: A cross sectional study enrolled 191 patients with cardiac problems. The study result revealed 53.4% of cases were males and 46.5% were females; the male to female ratio was 1: 1.14. The mean age of all patients was 51.9±4.6 years. The patients were examined and investigated for the presence of atrial fibrillation and then were divided into two groups, atrial fibrillation positive (20.5 %) and atrial fibrillation negative (77.5 %). Hyperuricemia was significantly associated with atrial fibrillation (P < 0.001) and the risk subjected by hyperuricemia was 3.5 in terms of odds ratio. Conclusion: There was significant association between hyperuricemia and presence of atrial fibrillation in patients admitted to CCU indicating that hyperuricemia is a risk factor for AF development