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The Distribution of Hepatitis C Virus Genotypes, Viral Load and Antibody Titer among Iraqi Chronic Hepatitis Patients


Affiliations
1 Department of Pharmacy, Al Rasheed University College, Baghdad, Iraq
2 Consultant Pathologist Physician, Al-Emamain Al-Kadhimain Medical City, Iraq
3 Departments of (Pathology and Forensic Medicine, Al-Nahrain University, Iraq
4 Microbiology, College of Medicine, Al-Nahrain University, Iraq
     

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Background: The infection by hepatitis C virus causedliver diseases such as:chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The current study aims to investigate the rate of HCV genotypes, subtypes, viral load and antibody immune response among Iraqi chronic hepatitis patients.

Methodology: During 2012-2017 period seventy-hundred and twenty tow hepatitis patients were referred to Middle East Laboratory from Baghdad and other provinces asking for HCV viral load, its genotype and anti-HCV antibody determination.

Results: A cross six years records, HCV genotype 4 was the most prevalent among Iraqi chronic hepatitis patients (46.68%), then genotype 1 (37.12%).There is notable changes in HCV genotypes distribution especially during 2017, where the genotype 1 predominantly found (52.63%). Although, these genotypes were none significantly associated with gender, age, viral load or anti-HCV antibody.

Conclusion: This recordindicates a recent change in the rate of HCV genotype 1 over genotype 4 infection in Iraqi chronic hepatitis patients.


Keywords

HCV, Genotypes, Chronic Hepatitis.
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  • The Distribution of Hepatitis C Virus Genotypes, Viral Load and Antibody Titer among Iraqi Chronic Hepatitis Patients

Abstract Views: 360  |  PDF Views: 0

Authors

Abdel Wahab A. R. Alshaikhly
Department of Pharmacy, Al Rasheed University College, Baghdad, Iraq
Zaidoon A. Musa
Consultant Pathologist Physician, Al-Emamain Al-Kadhimain Medical City, Iraq
Ban J. Qasim
Departments of (Pathology and Forensic Medicine, Al-Nahrain University, Iraq
Haider F. Ghazi
Microbiology, College of Medicine, Al-Nahrain University, Iraq
Wisam J. Mohammed
Department of Pharmacy, Al Rasheed University College, Baghdad, Iraq

Abstract


Background: The infection by hepatitis C virus causedliver diseases such as:chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The current study aims to investigate the rate of HCV genotypes, subtypes, viral load and antibody immune response among Iraqi chronic hepatitis patients.

Methodology: During 2012-2017 period seventy-hundred and twenty tow hepatitis patients were referred to Middle East Laboratory from Baghdad and other provinces asking for HCV viral load, its genotype and anti-HCV antibody determination.

Results: A cross six years records, HCV genotype 4 was the most prevalent among Iraqi chronic hepatitis patients (46.68%), then genotype 1 (37.12%).There is notable changes in HCV genotypes distribution especially during 2017, where the genotype 1 predominantly found (52.63%). Although, these genotypes were none significantly associated with gender, age, viral load or anti-HCV antibody.

Conclusion: This recordindicates a recent change in the rate of HCV genotype 1 over genotype 4 infection in Iraqi chronic hepatitis patients.


Keywords


HCV, Genotypes, Chronic Hepatitis.



DOI: https://doi.org/10.37506/v20%2Fi1%2F2020%2Fmlu%2F194454