Research Journal of Pharmacy and Technology

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Hypolipidemic Activity of Amaranthus Tristis Linn in Triton WR-1339 Induced Hyperlipidemic Rats


Affiliations
1 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, India
2 Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, India
     

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Hyperlipidemia is the greatest risk factor of coronary heart disease. Currently available hypolipidemic drugs have been associated with number of side effects. Herbal treatment for hyperlipidemia has no side effects and is relatively low cost and locally available.plant has been selected for this study present study. The aim is to perform on anti-hyperlipidemic activity of ethanolic extract of leaves of Amaranthus tristis Linn against Triton wr-1339 induced hyperlipidemia in rats. Amaranthus tristis Linn administered a dose of 200mg/kg (p.o) to the triton induced hyperlipidemic rats. Amaranthus tristis Linn shows a significant decrease in the levels of serum cholesterol, phospholipids, triglyceride, LDL, VLDL and significant increase in the level of serum HDL level.

Keywords

Amaranthus tristis Linn, Hyperlipidemia. LDL, VLDL, HDL.
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  • Hypolipidemic Activity of Amaranthus Tristis Linn in Triton WR-1339 Induced Hyperlipidemic Rats

Abstract Views: 193  |  PDF Views: 3

Authors

T. Sundarrajan
Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, India
M. Vijey Aanandhi
Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Vels University (VISTAS), Chennai, Tamil Nadu, India

Abstract


Hyperlipidemia is the greatest risk factor of coronary heart disease. Currently available hypolipidemic drugs have been associated with number of side effects. Herbal treatment for hyperlipidemia has no side effects and is relatively low cost and locally available.plant has been selected for this study present study. The aim is to perform on anti-hyperlipidemic activity of ethanolic extract of leaves of Amaranthus tristis Linn against Triton wr-1339 induced hyperlipidemia in rats. Amaranthus tristis Linn administered a dose of 200mg/kg (p.o) to the triton induced hyperlipidemic rats. Amaranthus tristis Linn shows a significant decrease in the levels of serum cholesterol, phospholipids, triglyceride, LDL, VLDL and significant increase in the level of serum HDL level.

Keywords


Amaranthus tristis Linn, Hyperlipidemia. LDL, VLDL, HDL.