Effect of Hesperidin for its Anti-Proliferative Activity on Liver Cancer and Cardio Vascular Diseases

Objective is to study the Plants that have served as a rich source of medicine including anti-cancer drugs. Research has shifted from the study of using extracts of whole or parts of plants to single active principles. Identification of cytotoxic agents led to the development of anticancer therapeutics with significant success but having severe side effects. Recent advances in understanding the molecular basis of cancer and development of high thorough screening methodologies have led to the discovery of novel therapies in the form of target-based drugs. Plant metabolites like flavonoids have fewer side effects and predominantly act by their capacity to scavenge free radicals, enzyme inhibition, and/or antiproliferative activity. Hesperidin is a biologically active flavonoid, is commonly found in citrus fruits and is used in Chinese medicine. It has been shown to have several useful pharmacological properties including blood lipid lowering activity.