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Antidiabetic Activity and Toxicity Studies of Ethanolic Extract of Polialthia longifolia Roots


Affiliations
1 Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, India
     

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Diabetic millets often referred to simply as diabetes (Ancient Greek: diabetes" to pass through [urine]") is a syndrome of disorder metabolism, usually due to a combination of hereditary and environment causes, resulting in abnormally high blood sugar level (hyperglycemia). Diabetes is described as starvation in the midst of plenty. Because the body will have high amount of glucose level but the cells are incapable of consume it because of osmotic difference Insulin is a hormone produced in the pancreas, which enable body cells to absorb glucose, to turn into energy. If the body cells cannot absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to acute metabolic complications including keto acidosis and in the long term contribute to chronic micro-vascular complications.

Keywords

Polialthia longifolia, Subacute Toxicity, Glibinclamide.
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  • Antidiabetic Activity and Toxicity Studies of Ethanolic Extract of Polialthia longifolia Roots

Abstract Views: 280  |  PDF Views: 3

Authors

D. Benito Johnson
Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, India
Akhil Raj
Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, India
R. Venkatanarayan
Department of Pharmacology, RVS College of Pharmaceutical Sciences, Sulur, Coimbatore, India

Abstract


Diabetic millets often referred to simply as diabetes (Ancient Greek: diabetes" to pass through [urine]") is a syndrome of disorder metabolism, usually due to a combination of hereditary and environment causes, resulting in abnormally high blood sugar level (hyperglycemia). Diabetes is described as starvation in the midst of plenty. Because the body will have high amount of glucose level but the cells are incapable of consume it because of osmotic difference Insulin is a hormone produced in the pancreas, which enable body cells to absorb glucose, to turn into energy. If the body cells cannot absorb the glucose, the glucose accumulates in the blood (hyperglycemia), leading to acute metabolic complications including keto acidosis and in the long term contribute to chronic micro-vascular complications.

Keywords


Polialthia longifolia, Subacute Toxicity, Glibinclamide.