The Prevalence of Serum IgG Antibody to Chlamydia trachomatis in Infertile Women at the University Hospital, Syria

Chlamydia trachomatis is considered one of the major Causes of sexually transmissible bacterial infection throughout the world. Infection can result in serious reproductive pathologies, including pelvic inflammatory disease, ectopic pregnancy, and infertility in women. Since there have been no previous studies dealing with chlamydial trachomatis in Syria, this study was conducted to define the role of Chlamydia trachomatis in female infertility. Method: it was a case- control study during the period from March to December 2015 Two groups of patients (n=23 infertile patients and n=21control patients) were enrolled in the study we obtained information about socio-demographic characteristics, and sexual behavior. Chlamydia trachomatis infection was detected by Enzyme Immunoassay (ELISA) for the quantitative determination of IgG antibodies specific to Chlamydia trachoamtis. Chlamydia trachoamtis antibodies were positive in 4/23 (17.1%) of the 23 infertile women while 1/21 (4.7%) in control group was positive. The difference was not statistically significant. But prevalence of Chlamydia trachoamtis antibody were high in infertile women. In view of the high incidence of Chlamydial infection in Syrian women with infertility. we recommend screening for anti. C.trachomatis antibodies using ELISA as part of routine investigations for infertility.