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Underlining some Important Aspects behind the Role of Enzyme Immobilization in Pharmaceutical Technology


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1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
     

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The objective of this review article is to discuss the potential of sodium alginate as a biopolymer in the formulation development and its allied applications. There is a growing trend in pharmaceutical in food industry to avoid the harsh condition in the preparation for administration to the body or for the storage purpose as it induce the side effects, instability or loss of therapeutic effect of the medicament. The immobilization method is a versatile functional biomaterial for viscosity enhancement, stabilizer, matrixing agent, encapsulation polymer, bio adhesive and film former in transdermal and transmucosal drug delivery. Among various tested methods of this process that make use of different enzyme-carrier interactions, immobilization by adsorption on solid carriers has appeared most common. According to these findings, in this review we present a comparative analysis of the literature reports on the recent trends in the immobilization of the enzymes by adsorption. In this review article, the various aspects of pharmaceutical microemulsin where compile together and the target audience are specifically the M. Pharm and B. Pharm student so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

Keywords

Immobilization, Adsorption, Cross Linking, Microencapsulation.
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  • Underlining some Important Aspects behind the Role of Enzyme Immobilization in Pharmaceutical Technology

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Authors

Simran Kukreja
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Sonal Priya
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Shraddha Bhondekar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Nupur Verma
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Sonal Jain
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Aivant Golchha
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Ganesh Sinha
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Shubham Kumar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Chandan Mandal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Asha Patel
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Mukta Agrawal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
D. K. Tripathi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Ajazuddin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Amit Alexander
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India

Abstract


The objective of this review article is to discuss the potential of sodium alginate as a biopolymer in the formulation development and its allied applications. There is a growing trend in pharmaceutical in food industry to avoid the harsh condition in the preparation for administration to the body or for the storage purpose as it induce the side effects, instability or loss of therapeutic effect of the medicament. The immobilization method is a versatile functional biomaterial for viscosity enhancement, stabilizer, matrixing agent, encapsulation polymer, bio adhesive and film former in transdermal and transmucosal drug delivery. Among various tested methods of this process that make use of different enzyme-carrier interactions, immobilization by adsorption on solid carriers has appeared most common. According to these findings, in this review we present a comparative analysis of the literature reports on the recent trends in the immobilization of the enzymes by adsorption. In this review article, the various aspects of pharmaceutical microemulsin where compile together and the target audience are specifically the M. Pharm and B. Pharm student so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

Keywords


Immobilization, Adsorption, Cross Linking, Microencapsulation.