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Emphasizing the Pharmaceutical Consideration behind the Development of Gastro-Retentive Dosage form


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1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
     

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Recent technological and scientific research has been devoted to the development of rate controlled drug delivery systems to overcome physiological adversities such as short gastric residence times and unpredictable gastric emptying times. The floating or hydro-dynamically controlled drug delivery systems are useful in such application. The objective of our review is to compile the recent advancements and developments regarding the novel dosage form i.e. the floating drug delivery systems (FDDS) that can be retained in the stomach for a prolonged period of time and gives therapeutic action in a predetermined manner. In these review article,the various aspects of pharmaceutical floating drug delivery system(FDDS) were compiled together and the target ordinance are specifically the M. Pharm and B Pharm students so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

Keywords

Gastric Retention, Oral Controlled Release System, Gastric Resistance, Emptying Time, FDDS.
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  • Emphasizing the Pharmaceutical Consideration behind the Development of Gastro-Retentive Dosage form

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Authors

Rita Devi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Vicky Soni
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Savej Malik
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Alok Singh
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Kundan Banjare
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Vikram Singh
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Tanuja Janghel
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Pooja Pal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Mukta Agrawal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
D. K. Tripathi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Ajazuddin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India
Amit Alexander
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh, 490024, India

Abstract


Recent technological and scientific research has been devoted to the development of rate controlled drug delivery systems to overcome physiological adversities such as short gastric residence times and unpredictable gastric emptying times. The floating or hydro-dynamically controlled drug delivery systems are useful in such application. The objective of our review is to compile the recent advancements and developments regarding the novel dosage form i.e. the floating drug delivery systems (FDDS) that can be retained in the stomach for a prolonged period of time and gives therapeutic action in a predetermined manner. In these review article,the various aspects of pharmaceutical floating drug delivery system(FDDS) were compiled together and the target ordinance are specifically the M. Pharm and B Pharm students so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

Keywords


Gastric Retention, Oral Controlled Release System, Gastric Resistance, Emptying Time, FDDS.