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Formulation Aspects behind the Development of a Stable Biphasic Liquid Dosage Form with Special Reference to Microemulsion


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1 Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
     

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Biphasic liquid dosage have an associated limitation of poor physical stability and therefore it is said to be thermodynamically unstable. Moreover, this area is also of great interest among the researchers towards the improvement of the stability. Thus, development of microemulsion systems is of great interest among the researchers. A microemulsion is a system of water, oil and amphiphilic compounds (surfactant and co-surfactant) which is a transparent, single opticalisotropic and thermodynamical stable liquid. Microemulsions are readily distinguished from normal emulsions by their transparency, low viscosity and more fundamentally their thermodynamic stability. In this review article, the various aspects of pharmaceutical microemulsion were compiled together and the target audiences are specifically the M. Pharm and B. Pharm students so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

Keywords

Microemulsion, Transparency, Amphiphilic.
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  • Formulation Aspects behind the Development of a Stable Biphasic Liquid Dosage Form with Special Reference to Microemulsion

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Authors

Shriya Gupta
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Sonali Dhokne
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Rameshwar Verma
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Manish Mitra
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Umesh Sahu
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Pitamber Bhardwaj
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Mohainish Bhoyar
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Manoj Biswas
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Lukesh Sahu
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Sheetal Jha
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Mukta Agrawal
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
D. K. Tripathi
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Ajazuddin
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India
Amit Alexander
Rungta College of Pharmaceutical Sciences and Research, Kohka-Kurud Road, Bhilai, Chhattisgarh 490024, India

Abstract


Biphasic liquid dosage have an associated limitation of poor physical stability and therefore it is said to be thermodynamically unstable. Moreover, this area is also of great interest among the researchers towards the improvement of the stability. Thus, development of microemulsion systems is of great interest among the researchers. A microemulsion is a system of water, oil and amphiphilic compounds (surfactant and co-surfactant) which is a transparent, single opticalisotropic and thermodynamical stable liquid. Microemulsions are readily distinguished from normal emulsions by their transparency, low viscosity and more fundamentally their thermodynamic stability. In this review article, the various aspects of pharmaceutical microemulsion were compiled together and the target audiences are specifically the M. Pharm and B. Pharm students so that their knowledge towards the subject concern can be enhanced and also at the same time can be motivated towards the publication.

Keywords


Microemulsion, Transparency, Amphiphilic.