Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Estimated of Some Biochemical Parameter in Patients Infected with Entamoeba histolytica in Maysan/Amarah Province, Iraq


Affiliations
1 Department of Biology, College of Science, AL-Mustansiriyah University, Baghdad, Iraq
     

   Subscribe/Renew Journal


The current study was carried out during the period from January 2017 to June 2017 in Maysan/ Amareh city for the detection of parasitic children infected with Entamoeba histolytica. One hundred child patients at the age’s group between 1-10 years old from both males and females with acute diarrhea clinically presented with bloody and mucoid diarrhea used to participate in the study. Samples collected from patient’s ( clinic paediatric in Shaheed Al - Sadr Teaching Hospital/Iraq, Al Zahrawi Surgical Hospitaland from the private laboratories City of Ammaraa ) and 25 persons as a healthy control .The results of biochemical parameters showed an elevated levels in liver the enzymes (GGT) and (LHD) was significantly higher than that observed in the non-patient (P<0.05).According to serum electrolytes , the serum level for, ionized calcium, and sodium were significantly lower for patients group (P<0.05). While for phosphorus and potassium there’s no significant difference between the patients group. The PH value for patients group (7.85) was significantly higher than non-patient (control group) (7.46).

Keywords

Entamoba histolytica, GGT, LDH, Serum Electrolyte.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Fotedar, R.; Stark, D.; Beebe, N.; Marriott, D.; Ellis, J. and Harkness, J. (2007). Laboratory Diagnostic Techniques for Entamoeba Species. Clinical Microbiology Reviews, 20(3): 511–532.

  • Haque, R.; and Petri, W. A. (2006). Diagnosis of amebiasis in Bangladesh. Arch. Med. Res., 37:273–276.

  • Damen, J. G.; Luka, J. and Lugos, M. (2011). Prevalence of Intestinal Parasites among Pupils in Rural North Eastern, Nigeria. Niger Med J., 52(1), 4-6.

  • Ozer, T.T.; Yula, E.; Deveci, O.; Tekin, A.; Durmaz, S.; Yanik, K. (2011) Investigation of Entamoeba histolytica in stool specimens by direct microscopic examination and ELISA in a hospital. Dicle Med J Cilt 38: 294–297.

  • Alghabban, A. (2014). Ginkgo bilobaleaf extract inhibits and treated Entamoeba histolytica infection. Nature and Science, 12(2): 63-68.

  • Teklu, W.; Tsegaye, T.; Belete S. and Takele, T. (2013). Prevalence of intestinal parasitic infections among high land and low land dwellers in Gamo area, South Ethiopia. BMC Public Health, 3, 151.

  • Wuerz, T.; Kane, J.B.; Boggild, K.; et al. (2012) a review of amoebic liver abscess for clinicians in a nonendemic setting. Can J Gastroenterol., 26(10):729-734.

  • Deneuville, T.; Mario, N.; Tiev, K.P.; Tole´dano, C.; Josselin-Mahr, L.; Gain, M.; et al. (2009). Concentration plasmatiquee´leve´e de la vitamine B12: unindicateur des maladies he´patiquesoutumorales? Rev Med Interne, 30(Suppl. 2):S73.

  • AL-Mahdawy, H.; Risan, F.; Mohammed Kh. (2016a). The level of IL-10, IL-17 and s.iga in patients with Entamoeba histolytica. European Journal of Biomedical and Pharmaceutical sciences, 3,(1):11-14

  • Frances, F. and Marshall B. D. (2009). A Manual of Laboratory and Diagnostic Tests. Lippincott William and Wilkins.8th ed. 286-290.

  • Allain, C. C. (1973). Quantitative determination of lactate dehydrogenase in serum. Clinical Chemistry, 19, 223-228.

  • Sirikutt, P. and Kalayanarooj, S. (2014). Serum lactate and lactate dehydrogenase as parameters for the prediction of dengue severity. J Med Assoc Thai., 97 Suppl 6:S220-31.

  • Marie, C. S., Verkerke, H. P., Paul, S. N., Mackey, A. J., and Petri, W. A. (2012). Leptin protects host cells from Entamoeba histolytica cytotoxicity by a STAT3-dependent mechanism. Infection and immunity, 80(5), 1934-1943.

  • Gowda, Sh.; Desai, P.; Hull, V.; Math, A.; Vernekar, S. and Kulkarni, Sh. (2009). A review on laboratory liver function tests. Pan Africa Medical Journal,

  • Rajgopal, G. and Rafi, K.M. (2005). Serum Gamma Glutamyltransferase (γ-GT) Activity in alcoholics with liver abscess and chronic alcoholics. Indian journal of clinical biochemistry, 20 (2): 198-199

  • Sharon, M. and Moe, M.D. (2008). Disorders Involving Calcium, Phosphorus, and Magnesium. Prim Care, 35(2): 215–vi.

  • Sharma, M. C. and Joshi, Ch. (2002). Serum Mineral and Haematobiochemical Profile of Microfilariae Infected Cattle in India: Its Effects on Production and Therapy Asian-Aust. J. Anim. Sci., 15(3): 357-365.

  • Al-Zuhairy, A.S.M.A. (2008). Biochemical parameters in sheep infected with toxoplasmosis. M.Sc. Thesis, College of Veterinary Medicine, University of Mosul.

  • Pingret, L.; Millot, J.M.; Sharonov, S.; Bonhomme, A.; Manfait, M. and Pinon, J.M. (1996). Relationship between intracellular free calcium concentrations and the intracellular development of Toxoplasma gondii. J. Histochem. Cytochem., 44(10): 1123-1129.

  • Davis, T.M., Li, G.Q. Guo, X.B. Spencer, J.L. John, S.t. (1993). Serum ionized calcium, serum and intracellular phosphate, and serum parathormone concentrations in acute malaria. Trans R Soc Trop Med Hyg., 87(1):49-53.

  • Kadir, M. and Hamad, N. (2013). Biochemical parameters in patients with Trichomonas vaginalis and Toxoplasma gondiiin Erbil-Iraq, Tikrit Journal of Pharmaceutical Sciences, 9, 2

  • Shah, G.S.; Das, B.K.; Kumar, S.; Singh, M.K. and Bhandari, G.P. (2007). Acid base and electrolyte disturbance in diarrhoea. Kathmandu Univ Med J (KUMJ)., 5(1):60-2.

  • Soentjens, P., Ostyn, B., Clerinx, J., Van Gompel, A., and Colebunders, R. (2005). A case of multiple amoebic liver abscesses: clinical improvement after percutaneous aspiration. Acta Clinica Belgica, 60(1), 29-33.

  • Davenport, M. and Syed, S.H.S. (2010) Hand book of pediatric surgery, ISBN: 978-1-84882-131-6


Abstract Views: 282

PDF Views: 0




  • Estimated of Some Biochemical Parameter in Patients Infected with Entamoeba histolytica in Maysan/Amarah Province, Iraq

Abstract Views: 282  |  PDF Views: 0

Authors

Nooraldeen Ali Jarullah
Department of Biology, College of Science, AL-Mustansiriyah University, Baghdad, Iraq
Shatha Khudairabbas
Department of Biology, College of Science, AL-Mustansiriyah University, Baghdad, Iraq
Rajwa H. Essa
Department of Biology, College of Science, AL-Mustansiriyah University, Baghdad, Iraq

Abstract


The current study was carried out during the period from January 2017 to June 2017 in Maysan/ Amareh city for the detection of parasitic children infected with Entamoeba histolytica. One hundred child patients at the age’s group between 1-10 years old from both males and females with acute diarrhea clinically presented with bloody and mucoid diarrhea used to participate in the study. Samples collected from patient’s ( clinic paediatric in Shaheed Al - Sadr Teaching Hospital/Iraq, Al Zahrawi Surgical Hospitaland from the private laboratories City of Ammaraa ) and 25 persons as a healthy control .The results of biochemical parameters showed an elevated levels in liver the enzymes (GGT) and (LHD) was significantly higher than that observed in the non-patient (P<0.05).According to serum electrolytes , the serum level for, ionized calcium, and sodium were significantly lower for patients group (P<0.05). While for phosphorus and potassium there’s no significant difference between the patients group. The PH value for patients group (7.85) was significantly higher than non-patient (control group) (7.46).

Keywords


Entamoba histolytica, GGT, LDH, Serum Electrolyte.

References