Open Access
Subscription Access
Open Access
Subscription Access
Herbal Drug Nanoparticles:Advancements in Herbal Treatment
Subscribe/Renew Journal
Herbal medicines have been used all over the world from last many years. Especially in India, there is wide market for herbals. Herbal medicines have less adverse effects as compared with modern medicines. The delivery of plant/herbal therapeutic molecules as drugs is problematic due to poor solubility, poor permeability, low bioavailability, instability in biological milieu and extensive first pass metabolism. These limitations of herbal drugs can be overcome by attaching or encapsulating them with suitable nanomaterials. Over the past decade, major advances have been made on development of novel drug delivery systems (NDDS) from plant actives and extracts. By developing new formulation as nano herbal medicines like nanoparticles, dendrimers, Nano crystals, Quantum dots, Nanosperes, Nanocapsules, herbal market get good feedback. The new approach in herbals as nanotechnology have a sound future which has a scientific approach to deliver the component in sustained manner which increase the patient compliance and avoid repeated administration. So many conditions like bacterial infection, hepatotoxicity, inflammation, oxidation and chronic diseases like cancer, wound healing can be cured by nano herbals more effectively as compared to allopathic medicines. The next most important step for herbal formulations is their standardization which establishes consistent biological activity, consistent chemical profile or simply a quality assurance program. This review will provide information of the use of nanotechnology for herbal drugs, nanoparticles, formulation techniques of nanoparticles and their standardization.
Keywords
Nanotechnology, Herbal Remedies, Formulation Techniques of Nanoparticles, Standardization of Herbal Drugs.
Subscription
Login to verify subscription
User
Font Size
Information
- Patel JS et al., Nanotechnology: A new approach in Herbal Medicine. American Journal of Pharmtech Research. 3(4); 2013: 275-288.
- Sharma M et al., Applications of Nanotechnology Based Dosage Forms for Delivery of Herbal Drugs. Research and reviews: journal of pharmaceutics and nanotechnology. 2(1); 2014: 23-30.
- Thapa RK et al., Herbal Medicine Incorporated Nanoparticles: Advancements in Herbal Treatment. Asian journal of biomedical and pharmaceutical sciences. 3(24); 2013: 7-14.
- Dhiman A et al., Novel Herbal Drug Delivery System (NHDDS): the need of Hour.2012 International Conference on Environment, Chemistry and Biology. 49(34); 2012: 171-175.
- Abirami A et al., Herbal nanoparticle for anticancer potential- a review. World journal of pharmacy and pharmaceutical sciences. 3(8); 1014: 2123-2132.
- Shahu AN et al., Nanotechnology in herbal medicines and cosmetics. International. Journal Research. Ayurveda Pharm. 4(3); 2013: 472-474.
- Choudhary N and Sekhon B et al., An overview of advances in the standardization of herbal drugs. Journal Pharm Educ Res. 2(2); 2011: 55-70.
- Ansari SH et al., Influence of nanotechnology on herbal drugs: A Review. J Adv Pharm Technol Research. 3(3); 2012: 142–146.
- Yadav D, et al. Novel approach: Herbal remedies and natural products in pharmaceutical science as nano drug delivery systems. International Journal Of Pharmacy and Technology.(3)3; 2011: 3092–3116.
- Kharat A and Pawar P et al., Novel drug delivery system in herbals. International journal of pharmaceutical, chemical and biological sciences. 4(4); 2014: 910-930.
- Abhilash M et al., Potential applications of Nanoparticles. International Journal of Pharma and Bio Sciences 1(1); 2010: 1-12.
- Sahni JK et al., Promising Role of Nanopharmaceuticals in Drug Delivery. Pharma Times. 43; 2011; 16–8.
- Lachman L and Lieberman HA., The Theory and Practice of Industrial Pharmacy. New York; 3 rd ed: pp. 420.
- Sheehan D, Blackwell W. Physical biochemistry. 2009; 285.
- Fessi H, et al., Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int J Pharm. 1989; 55:R1- 4.
- Back BM.et al., Department of pharmaceutics and biopharmacy, Eur. J Pharm Science. 2010; Oct.9.
- Jung J, Perrut M.et al., Particle design using supercritical fluids: Literature and patent survey. Journal of Supercrit Fluids. 20; 2001: 179–219. 18. Pal SL et al., Nanoparticle: An overview of preparation and characterization. Journal of Applied Pharmaceutical Science. 1(6); 2011: 228-234.
- Chimezie A et al., HPLC analysis of nicotinamide, pyridoxine, riboflavin and thiamin in some selected food products in Nigeria. Afr J Pharm Pharmacol. 2(2); 2008: 29-36.
- Saravanan J et al., A simple and validated RP-HPLC method for the estimation of methylcobalamin in bulk and capsule dosage form. Int J Chem Pharm Sci. 1(2); 2010: 323-324.
- Choudhary N, Sekhon B et al., An overview of advancesin the standardization of herbal drugs. J Pharm Educ Res.2 (2); 2011:55-77 (Anupam S, Krishan L, Handa SS. Standardization: HPLC determination of vasicine in polyherbal formulations. Pharm Biol; 30(3); 1992: 205-208.)
- Bose A et al., A review on latest developments in the standardization of ayurvedic drugs. International journal of pharmaceutical research and bio-science. 3; 2012: 96-119. (Singh DP, Govindarajan R, Rawat AKS. High-performance liquid chromatography as a tool for the chemical standardization of Triphala an ayurvedic formulation. Phytochem Anal. 19(2); 2007: 164-168.)
- Zhang Q, Ye M et al., Chemical analysis of the Chinese herbal medicine Gan-Cao (licorice). J Chromatogr A. 1216(11); 2009:1954-1969.
- Kumar A et al., Estimation of gallic acid, Rutin, and Quercetin in Terminalia chebula by HPTLC. Jordan Journal of Pharmaceutical Sciences. 3(1); 2010: 63-68.
- 25. Jirge SS et al., Development and validation of a novel HPTLC method for simultaneous estimation of beta-sitosterol- d-glucoside and Withaferin A. Int J Pharm Pharmaceut Sci.; 3(Suppl 2); 2011: 227-230.
- Shanbhag DA, Khandagale NA.et al., Application of HPTLC in the standardization of a homoeopathic mother tincture of Syzygium jambolanum. J Chem Pharm Res. 3(1); 2011: 395-401.
- Kasthuri KT. et al., Development of GC-MS for a polyherbal formulation- MEGNI. International Journal of Pharmaceutical sciences, 2 (2), 2010, 81-83.
- Li SL, et al. Decocting-induced chemical transformations and global quality of Du–Shen–Tang, the decoction of ginseng evaluated by UPLC–Q-TOF-MS/MS based chemical profiling approach. J Pharm Biomed Anal 53(4); 2010: 946–957.
- Li SL, et al. UPLC– PDA–TOFMS based chemical profiling approach to rapidly evaluate chemical consistency between traditional and dispensing granule decoctions of traditional medicine formulae. J Pharm Biomed Anal.52 (4); 2010:468–478.
- Mike Lee S, Edward Kerns H.et al., LC/MS applications in drug development. Milestone Development Services, Pennington, New Jersey. 1999:187-279.
- 31. Shen AQ .et al. Tandem Method development of LC-MS analysis of aminoglycoside drugs: Challenges and solutions. Answering Pharmaceutical Questions with Discipline and Ingenuity; 5(2); 2010:567-569.
- Binit Kumar Dwivedi, et al. Gas chromatography mass spectrometry (GC-MS) analysis of the hexane and benzene extracts of the Piper beetle from India. J Med Plant Res. 4(21); 2010: 2252-2255.
- Gatkal S, et al. Safety of herbal medicine: a review. International journal of pharmaceutical and chemical sciences. 1(4); 2012: 1624-1639.
- 34. Shaa YF.et al., Analysis of Rhioxma Curcumae Aeruginosae volatiles by solid-phase microextraction with gas chromatography-massspectrometry. Z. Naturforsch. 2004; 59(7-8): 533-537.
- Ganzera M.et al., Quality control of herbal medicines by capillary electrophoresis: Potential, requirements and applications. Electrophoresis 29:2008; 3489–3503.
- Wen HG, et al. Analysis of protoberberine alkaloids in several herbal drugs and related medicinal preparations by non-aqueous capillary electrophoresis. J Sep Sci. 28(1); 2005: 92-97.
- 37. Pietta P. et al., Application of micellar electrokinetic capillary chromatography to the determination of flavonoid drugs. J Chromatogr; 549; 1991: 367-373.
- Sombra LL.et al., Comparative study between capillary electrophoresis and high performance liquid chromatography in „guarana‟ based phytopharmaceuticals. J Pharm Biomed Anal 36:2005; 989–994.
- Tistaert C.et al.,Chromatographic separation techniques and data handling methods for herbal fingerprints: A review. Anal Chim Acta. 690(2); 2011: 148–161.
- Anupam Kumar Sachan* and Ankita Gupta.et al., A review on nanotized herbal drugs.International journal of pharmaceutical sciences and research.
- Yen FL.et al., Nanoparticles formulation of Cuscuta chinensis prevents acetaminophen-induced hepatotoxicity in rats. Food Chem Toxicol 46:2008; 1771-1777.
- Soheir N. et al.,: Quercetin Nanoparticles: Preparation and Characterization. Indian Journal of Drugs. 2(3); 2014: 96-103.
Abstract Views: 281
PDF Views: 0