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Screening of In vitro Antioxidant Activity of Methanolic extract of Maruthampattai kudineer- A Siddha Polyherbal Preparation


Affiliations
1 Dept. of Sirappu Maruthuvam, National Institute of Siddha, Chennai-47, India
2 Central Council for Research in Siddha, Chennai-47, India
3 Greensmed Labs, Thoraipakkam, Chennai -600097, India
4 National Institute of Siddha, Chennai-47, India
     

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Siddha medical system is one of the renowned traditional system of India which is gaining popularity in recent days. Therefore scientific documentation of the siddha formulations has become the need of the hour. The aim of the study was to evaluate in vitro antioxidant potential of methanolic extract of Maruthampattai kudineer, a polyherbal siddha formulation indicated in siddha text for the management of diabetes. One of the major causative factor implicated is the damage induced by free radicals in the development of diabetes and its complications and hence an antidiabetic compound with antioxidant properties would be more favourable. Therefore, the anti-oxidant properties of this formula were studied by using 2, 2- diphenyl-1-picryl-hydrazyl (DPPH) assay, reducing power activity and [2, 2’-azino-bis (3- ethylbenzthiazoline-6-sulphonic acid)] ABTS assay.

Keywords

Siddha, Maruthampattai Kudineer, Anti-Oxidant Properties.
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  • Indap MM, et al; Evaluation of antioxidant and anticlastogenic properties of sponge Tetheya lynevrium [Linn]. Indian drugs No.45 aso:9 Sep:2008

  • T. Thirunarayanan, Introduction to siddha medicine, Centre for traditional medicine and research 2012;189-192

  • Mahishi P, et al; Medicinal plant wealth of local communities in some villages in Shimoga District of Karnataka, India.J Ethnopharmacol. 2005; 98: 307- 312.

  • Devasagayam TPA, et al. Review: Free radicals and antioxidants in human health:

  • Curr Stat Fut Prosp. JAPI. 2004; 52: 794-804. Modak, M., et al; Indian Herbs and Herbal Drugs Used for the Treatment of Diabetes. Journal of Clinical Biochemistry and Nutrition, 40(3), 163–173, (2007).

  • Agathiyar – 2000, First edition, may 1997.

  • International Journal of Pharmacology, 7(2), 2011, 248-256.

  • Molecules, 15, 20s10, 5547-5560

  • Isabel C.F.R. Ferreira et al; Free-radical scavenging capacity and reducing power of wild edible mushrooms from northeast Portugal: Individual cap and stipe activity. Food Chemistry 100 (2007) 1511–1516

  • Yildirim A, et al; Determination of antioxidant and antimicrobial activities of Rumex crispus L. extracts. J Agri Food Chem. 2001, 49(8), 4083-4089.

  • Nassar MI, et al; Chemical constituents of clove (Syzygium aromaticum Fam. Myrtaceae) and their antioxidant activity. Revista Latinoamericana de Química 2007; 35(3): 47-57.

  • Jian-Ming Lu,et al; Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems.J Cell Mol Med. 2010; 14: 840–860.

  • P. Jayanthi et al; Reducing power of the solvent extracts of Eichhornia crassipes (mart.) Solms; International journal of pharmacy and pharmaceutical sciences issn- 0975-1491 vol 3, suppl 3, 2011

  • M. R. Sahaa , et al; In vitro free radical scavenging activity of methanol extract of the leaves of mimusops elengi linn. J. Vet. Med. (2008). 6 (2): 197–202

  • M. Vijibala, et al; Evaluation of Antioxidant potential of the Siddha Formulation Sambirani Poo Kuligai by in-vitro DPPH radical scavenging assay Int. J. Adv. Res. Biol. Sci. (2017). 4(12): 257-261

  • Bharathkumar, G, et al; Antioxidant and Hepatoprotective Potential of the Aqueous Decoction from Siddha Formulation Drug; International Journal of Current Research 9, (05), 50435-50443

  • KR. Nagulendran,, et al; “In vitro Antioxidant Activity and Total Polyphenolic Content of Cyperus rotundus Rhizomes,” E-Journal of Chemistry, vol. 4, no. 3, pp. 440-449, 2007

  • Fatmah A Matough,*1 et al; The Role of Oxidative Stress and Antioxidants in Diabetic Complications Sultan Qaboos University Medical Journal. 2012 Feb; 12(1)5


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  • Screening of In vitro Antioxidant Activity of Methanolic extract of Maruthampattai kudineer- A Siddha Polyherbal Preparation

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Authors

B. Vinubharathi
Dept. of Sirappu Maruthuvam, National Institute of Siddha, Chennai-47, India
V. Mahalakshmi
Dept. of Sirappu Maruthuvam, National Institute of Siddha, Chennai-47, India
N. J. Muthukumar
Central Council for Research in Siddha, Chennai-47, India
R. Suresh
Greensmed Labs, Thoraipakkam, Chennai -600097, India
V. Banumathi
National Institute of Siddha, Chennai-47, India

Abstract


Siddha medical system is one of the renowned traditional system of India which is gaining popularity in recent days. Therefore scientific documentation of the siddha formulations has become the need of the hour. The aim of the study was to evaluate in vitro antioxidant potential of methanolic extract of Maruthampattai kudineer, a polyherbal siddha formulation indicated in siddha text for the management of diabetes. One of the major causative factor implicated is the damage induced by free radicals in the development of diabetes and its complications and hence an antidiabetic compound with antioxidant properties would be more favourable. Therefore, the anti-oxidant properties of this formula were studied by using 2, 2- diphenyl-1-picryl-hydrazyl (DPPH) assay, reducing power activity and [2, 2’-azino-bis (3- ethylbenzthiazoline-6-sulphonic acid)] ABTS assay.

Keywords


Siddha, Maruthampattai Kudineer, Anti-Oxidant Properties.

References