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Evaluation of An Ayurvedic Polyherbal Formulation through TLC Fingerprint Profile of Volatile Oils:A Quality Control Approch


Affiliations
1 Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute, A. A. Hospital Campus, Arumbakkam, Chennai - 600106, India
2 Central Council for Research in Ayurvedic Science, Janakpuri, Ministry of AYUSH, New Delhi - 110058, India
     

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The present study was carried out for evaluation of TLC fingerprint profiles of volatile oils/essential oils of the each ingredient of the polyherbal formulation of Trikatu churna and comparison of the volatile oil of the finished product or formulation as such. Essential oils/volatile oil contents are characteristic to the ingredients or raw botanicals to identify them easily. In the raw botanicals, where ever its presence is possible and its verification through the TLC/HPTLC fingerprint profile is the one of the best ways to identify and evaluate the quality of the finished formulation in the course of development of a standardization protocol as a quality control tool.

Keywords

Volatile Oil, HPTLC, Fingerprint Profile, Poly Herbal Formulation, Standardization and Quality Control.
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  • Aneesh, Mohamed Hisham, M Sonal Sekhar, Manjusree Madhu, Deepa T.V. International market scenario of traditional Indian herbal drugs - India declining’, IJGP, (2009) 3(3):184-190

  • N.B. Joshi, M.B. Shankar. Global Market Analysis of Herbal Drug Formulations. Int. J. Ayu. Pharm. Chem. 4 (2015) 59-65.

  • M. Rajani, N.S. Kanaki, Phytochemical standardization of herbal drugs and polyherbal formulations. In: (Eds. K. G. Ramawat, J. M. Merillon) Bioactive Molecules and Medicinal Plants. Springer-Verlag, Berlin Heidelberg. (2008) 349-369.

  • E.Guenther, The essential oils. New York, D. Van Nostrand Company, Inc.

  • F. Bakkali, B. Averbeck, D. Averbeck, M. Idaomar. Biological effects of essential oils--a review. Food and Chemical Toxicology, 46 (2008) 446–475.

  • T. Hasselstrom, E.J. Hewitt, K.S. Konigsbacher, J. J. Ritter. Composition of volatile oil of black pepper. J. Agric. Food Chem. 5 (1957) 53-55.

  • C.J. Muller, W.G. Jennings. Constituents of black pepper, some sesquiterpene hydrocarbons. J. Agric. Food Chem. 15 (1967) 762–766.

  • W.G. Jennings, R.E. Wrolstad. Volatile Constituents of Black Peppera. J Fd Sci. 26 (1961) 499-509.

  • K.L. Handa, N.C. Nigam, M.L. Sharm, Perfume Kosmetik, 44 (1963) 233-235.

  • M.C. Nigam, I.C. Nigam, L. Levi, K.L. Handa. Essential oils and their constituents: xxii. Detection of new trace components in oil of ginger. Can J Chem. 42 (1964) 2610-2615.

  • S. Sultana, M. Ali. Chemical composition of volatile oil of the rhizome of Zingiber officinale Roscoe. and its antimicrobial activity. World J. of Pharmacy and Pharmaceutical Sci. 4 (2015) 741-752.

  • D.W. Connell. The chemistry of the essential oil and oleoresin of ginger (Zingiber officinale Roscoe). Flavour Ind. 1 (1970) 677.

  • A.G. Mathew, N. Krishnamurthy, E.S. Nambudri, Y.S. Lewis,. Oil of ginger. Flavour Ind. 3 (1973) 78–81.

  • Anonymous. The Ayurvedic Formulary of India. Part I, 2nd Edn. Government of India, Ministry of Health and Family Welfare, New Delhi, 2003.

  • WHO, Quality Control Methods for Medicinal Plant Materials, Geneva 1998 34-37.

  • P. D. Sethi, High Performance Thin Layer Chromatography (1st Edition). CBS Publishers and Distributors, New Delhi, X (1996).

  • I. Stahl, Thin Layer Chromatography. A Laboratory Hand Book (Student Edition). Springer-Verlag, Berlin, (1969).

  • H. Wagner, S. Baldt, E.M. Zgainski, Plant drug analysis. Berlin Springer, (1996).

  • Kunle, O. Folashade, Egharevba, H. Omoregie, Ahmadu, P. Ochogu. Standardization of herbal medicines - A review. Int. J. Biodiv. Con. 4 (2012) 101-112.

  • Z.Y. Liang, P. Xie, K. Chan. Quality control of herbal medicines. J. Chromb., 812 (2004) 53-70.


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  • Evaluation of An Ayurvedic Polyherbal Formulation through TLC Fingerprint Profile of Volatile Oils:A Quality Control Approch

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Authors

Cheemalapati Venkata Narasimhaji
Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute, A. A. Hospital Campus, Arumbakkam, Chennai - 600106, India
A. K. Meena
Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute, A. A. Hospital Campus, Arumbakkam, Chennai - 600106, India
B. Maheshwari
Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute, A. A. Hospital Campus, Arumbakkam, Chennai - 600106, India
Arjun Singh
Central Council for Research in Ayurvedic Science, Janakpuri, Ministry of AYUSH, New Delhi - 110058, India
Ravindra Singh
Central Council for Research in Ayurvedic Science, Janakpuri, Ministry of AYUSH, New Delhi - 110058, India
R. Ilavarasan
Captain Srinivasa Murthy Regional Ayurveda Drug Development Institute, A. A. Hospital Campus, Arumbakkam, Chennai - 600106, India

Abstract


The present study was carried out for evaluation of TLC fingerprint profiles of volatile oils/essential oils of the each ingredient of the polyherbal formulation of Trikatu churna and comparison of the volatile oil of the finished product or formulation as such. Essential oils/volatile oil contents are characteristic to the ingredients or raw botanicals to identify them easily. In the raw botanicals, where ever its presence is possible and its verification through the TLC/HPTLC fingerprint profile is the one of the best ways to identify and evaluate the quality of the finished formulation in the course of development of a standardization protocol as a quality control tool.

Keywords


Volatile Oil, HPTLC, Fingerprint Profile, Poly Herbal Formulation, Standardization and Quality Control.

References