Research Journal of Pharmacy and Technology

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A Comparative Study on Phytochemical Screening, Antioxidant and Antimicrobial Capacities of Leaf Extracts from Medicinal plants


Affiliations
1 School of Biosciences and Technology, VIT University,Vellore-632014, Tamil Nadu, India
2 School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore–632014, Tamil Nadu, India
     

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The aim of this work is to investigate and compare the phytochemical screening, antioxidant and antimicrobial activities of plant crude extracts from leaves of four different medicinal plants Mukia maderaspatana, Cissus quadrangularis, Portulaca quadrifida, Pisonia Alba. Methanol and Petroleum ether solvent were used to prepare the crude extracts from leaves. Antioxidant and antimicrobial activities of different crude extracts were determined by DPPH method and agar disc diffusion method. Antibacterial activity was carried out against five different organisms (Escherichia coli (MTCC: 1687), Bacillus cereus (MTCC: 0430), Klebsiella pneumoniae (MTCC: 7028), Staphylococcus aureus(MTCC: 3160), Proteus mirabilis (MTCC: 3310). And the antifungal activity against A.niger (MTCC 281) and A.flavus (MTCC 10938). All the extracts showed a promising antibacterial activity. Hence, the outcomes of the present research suggest that the potential antioxidant and antimicrobial activity of these different plants may be responsible for its wide traditional use as medicine.

Keywords

Medicinal Plants, Antimicrobial Activity, Antioxidant, DPPH, Phytochemical Analysis.
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  • Ajlan A. Medicinal Plants : A Review. Natural Products :An Indian Journal. 12(3); 2016: 1–6.

  • Ravi L et al. Antibacterial and Antioxidant Activity of Saponin From Abutilon Indicum Leaves. Asian Journal of Pharmaceutical and Clinical Research. 9; 2016: 344–347.

  • Singh R. Medicinal plants : A review. Journal of Plant Sciences. 3(1-1); 2015: 50–55.

  • Sangeetha G., Vidhya, R. In vitro anti-inflammatory activity of different parts of Pedalium murex (L.). International Journal of Herbal Medicine. 4(43); 2016: 31–36.

  • Mahalingam R et al. Studies on antibacterial activity of some medicinal plant against Human pathogenic Micro Organism. Pelagia Research Library. 1(3); 2011: 86–90.

  • Kavitha M et al. Evaluation of Nutrient Composition and Antibacterial Potential of Leaf and Stem of Mukia Maderaspatanal. International Journal of Pharmaceutical Research & Allied Sciences. 2(3); 2013: 68–76.

  • Raja B., Pugalendi K. V. Evaluation of antioxidant activity of Melothria maderaspatanain vitro. Central European Journal of Biology. 5(2); 2010: 224–230.

  • Shah U. Cissus quadrangularis L.: Phytochemicals, traditional uses and pharmacological activities-A review. International Journal of Pharmacy and Pharmaceutical Sciences.3; 2011: 41–44.

  • Sathiavelu A. et al. In Vitro anti-diabetic activity of aqueous extract of the medicinal plants Nigella sativa, Eugenia jambolana, Andrographis paniculataand Gymnema sylvestre. International Journal of Drug Development and Research.5 (2); 2013: 323–328.

  • Manivannan E. et al. Hepatoprotective Activity of Portulaca quadrifida Linn against CCl4 Induced Hepatotoxicity in Rats. Research and reviews: journal of pharmacy and pharmaceutical sciences.3(2); 2014: 2320–2323.

  • Verma Sc et al. Phytochemical and High-Performance Liquid Chromatography Analysis of Extract of Portulaca QuadrifidaLinn .Asian Journal of Pharmaceutical and Clinical Research. 9(3); 2016: 2–3.

  • Prabakaran S et al. Hepatoprotective effect of Pisonia alba and Cardiospermum halicacabum in atrazine toxicity on LPO and some antioxidant activities in the liver tissue of fresh water fish Labeo rohita. International Journal of Pharmaceutical and Biological Archives.5(2); 2014: 174–179.

  • Saritha B. et al. Studies on antioxidant activity, phenol and flavonoid content of Pisonia Alba Span. Asian Journal of Pharmaceutical and Clinical Research.7(3); 2014: 106–109.

  • Vadivelan R et al. Antidiabetic Activity of Mukia maderaspatana (L) Roem in Alloxan Induced Diabetic Rats. Research J. Pharmacology and Pharmacodynamics.2(1); 2010: 78–80.

  • Justin Raj S., Joseph B. Pharmacognostic and traditional properties of Cissus quadrancularis Linn -an overview. International Journal of Pharma and Bio Sciences. 2(1); 2011: 131–139.

  • Meena H. et al. Evaluation of antioxidant activity of two important memory enhancing medicinal plants Baccopamonnieri and Centella asiatica. Indian Journal of Pharmacology.44(1); 2012: 114–117.

  • Ranjitha Dhevi V. Sundar et al. Bioactivity of phoenixdactylifera seed and its phytochemical analysis. International Journal of Green Pharmacy.11(2); 2017: 1–11.

  • Baba S. A., Malik S. A. Determination of total phenolic and flavonoid content, antimicrobial and antioxidant activity of a ischolar_main extract of Arisaema jacquemontii Blume. Journal of Taibah University for Science. 9 (4); 2015: 449–454.

  • Sahu R. K. et al. DPPH Free Radical Scavenging Activity of Some Leafy Vegetables used by Tribals of Odisha. India. Journal of Medicinal Plant Studies. 1(4); 2013: 21–27.

  • Prince L., Prabakaran P. Antifungal activity of medicinal plants against plant pathogenic fungus Colletotrichum falcatum. Asian Journal of Plant Science and Research. 1 (1); 2011: 84–87.

  • Moumita banerjee, Thankamani V. Antimicrobial activity of plant Mukia maderaspatana. International journal of Pharmacy and Pharmaceutical sciences . 5; 2013: 199-202.

  • Vishnupriya C., Ahmed F. Potency of Two Commonly Available Plants Pisonia alba and Mukia maderaspatana in the Health Industry. International of Current Microbiology and Applied Science. 6 (1);2017: 721–732.


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  • A Comparative Study on Phytochemical Screening, Antioxidant and Antimicrobial Capacities of Leaf Extracts from Medicinal plants

Abstract Views: 235  |  PDF Views: 0

Authors

Ranjitha Dhevi V. Sundar
School of Biosciences and Technology, VIT University,Vellore-632014, Tamil Nadu, India
Mythili Sathiavelu
School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore–632014, Tamil Nadu, India

Abstract


The aim of this work is to investigate and compare the phytochemical screening, antioxidant and antimicrobial activities of plant crude extracts from leaves of four different medicinal plants Mukia maderaspatana, Cissus quadrangularis, Portulaca quadrifida, Pisonia Alba. Methanol and Petroleum ether solvent were used to prepare the crude extracts from leaves. Antioxidant and antimicrobial activities of different crude extracts were determined by DPPH method and agar disc diffusion method. Antibacterial activity was carried out against five different organisms (Escherichia coli (MTCC: 1687), Bacillus cereus (MTCC: 0430), Klebsiella pneumoniae (MTCC: 7028), Staphylococcus aureus(MTCC: 3160), Proteus mirabilis (MTCC: 3310). And the antifungal activity against A.niger (MTCC 281) and A.flavus (MTCC 10938). All the extracts showed a promising antibacterial activity. Hence, the outcomes of the present research suggest that the potential antioxidant and antimicrobial activity of these different plants may be responsible for its wide traditional use as medicine.

Keywords


Medicinal Plants, Antimicrobial Activity, Antioxidant, DPPH, Phytochemical Analysis.

References