Research Journal of Pharmacy and Technology

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Oral Dispersible Films, Novel Technology for the Delivery of Drugs


Affiliations
1 Department of Pharmaceutics, N.G.S.M. Institute of Pharmaceutical Sciences, NITTE Deemed to be University, Paneer, Deralakatte, Mangalore – 575018, India
     

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Various dosage forms have been introduced in the recent days in the field of pharmaceutical technology. Transdermal patch is a technique from which a new drug delivery system that is oral dispersible film was developed. Oral dispersible films when they placed on mouth or oral cavity, they disintegrate or dissolve within a minute. Even though in a solid dosage form it doesn’t require chewing or drinking of water, which enhances the patient compliance. There are number of ingredients are used to formulate oral dispersible patches, like active pharmaceutical ingredients, polymers, flavouring agents, colouring agents etc, in which we can regard polymer as important ingredient which helps to form the film. Usually hydrophobic polymer are used for oral dissolving films which breaks down on the tongue or buccal cavity and then drug will go to systemic circulation. Fast disintegrating property, good mechanical property like mouth dissolving property of film can be achieved by water soluble polymer. Moreover in oral dispersible films, accurate and effective dosing can be accomplished in a safe manner.

Keywords

Oral Dispersible Films, Hydrophilic Polymers, Plasticizers, Solvent Casting.
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  • Oral Dispersible Films, Novel Technology for the Delivery of Drugs

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Authors

Jobin Jose
Department of Pharmaceutics, N.G.S.M. Institute of Pharmaceutical Sciences, NITTE Deemed to be University, Paneer, Deralakatte, Mangalore – 575018, India
P. B. Ashwini
Department of Pharmaceutics, N.G.S.M. Institute of Pharmaceutical Sciences, NITTE Deemed to be University, Paneer, Deralakatte, Mangalore – 575018, India
Prashant Nayak
Department of Pharmaceutics, N.G.S.M. Institute of Pharmaceutical Sciences, NITTE Deemed to be University, Paneer, Deralakatte, Mangalore – 575018, India
R. Narayana Charyulu
Department of Pharmaceutics, N.G.S.M. Institute of Pharmaceutical Sciences, NITTE Deemed to be University, Paneer, Deralakatte, Mangalore – 575018, India

Abstract


Various dosage forms have been introduced in the recent days in the field of pharmaceutical technology. Transdermal patch is a technique from which a new drug delivery system that is oral dispersible film was developed. Oral dispersible films when they placed on mouth or oral cavity, they disintegrate or dissolve within a minute. Even though in a solid dosage form it doesn’t require chewing or drinking of water, which enhances the patient compliance. There are number of ingredients are used to formulate oral dispersible patches, like active pharmaceutical ingredients, polymers, flavouring agents, colouring agents etc, in which we can regard polymer as important ingredient which helps to form the film. Usually hydrophobic polymer are used for oral dissolving films which breaks down on the tongue or buccal cavity and then drug will go to systemic circulation. Fast disintegrating property, good mechanical property like mouth dissolving property of film can be achieved by water soluble polymer. Moreover in oral dispersible films, accurate and effective dosing can be accomplished in a safe manner.

Keywords


Oral Dispersible Films, Hydrophilic Polymers, Plasticizers, Solvent Casting.

References