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The GC MS Study of one Ayurvedic Medicine, Vasakadyaristam


Affiliations
1 Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, India
2 Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, India
3 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, India
4 Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, India
5 Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai- 600073, India
     

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The present study deals with the GC MS analysis of one Ayurvedic prepaation, Vasakadyarishtam, which is a mucolytic medicine used for the treatment of cough, cold, chest congestion asthma and related diseases like bronchitis, inflammation and hemoptysis. The most important constituent of this medicine is Vasaka or Adhatoda vesika plant, which is known for its anti-cough and cold usage in Ayurveda. This study was to understand the main biomolecules present in this medicine by GC MS analysis. The results indicted the presence of some important molecules such as Eucalyptol, Phenylethyl alcohol, Camphor, Ethyl hydrogen succinate, Succinic acid, cyclobutyl ethyl ester, 3-Cyclohexen-1-ol,4-methyl-(1-methylethyl)-(R)-,. alpha.-Terineol, 5- Hydroxymethyl furfural, p-Anisic acid,4-nitrophenyl ester, 2-Propen-1-0l,3-phenyl, Benzeneethanol, 4-hydroxy- Propiophenone, 2‘-(trimethylsioxy)-, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester and Octadecanoic acid and 2,3 –dyhydroxypropyl ester. These molecules are known for their various medicinal properties which indicate their roles in this formulation.

Keywords

Vasakadyarishtam, Adhatoda vesika, Eucalyptol, Phenylethyl Alcohol, Camphor, Ethyl Hydrogen Succinate, Alpha.-Terineol.
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  • Md. Tofazzal Hossain, Md. Obydul Hoq. Therapeutic use of Adhatoda vasica. Asian J Med Biol Res, 2016; 2 (2): 156-163
  • Sandeep Dhankhar, Ramanjeet Kaur , Ruhil S , Balhara M, Seema Dhankhar , Chhillar AK. A review on Justicia adhatoda: A potential source of natural medicine. African Journal of Plant Science, 2011; 5(11): 620-627
  • Dubey D, Patnaik R, Ghosh G, Padhy RN. In Vitro Antibacterial Activity, Gas Chromatography–Mass Spectrometry Analysis of Woodfordia fruticosa Kurz. Leaf Extract and Host Toxicity Testing With In Vitro Cultured Lymphocytes from Human Umbilical Cord Blood. Osong Public Health and Research Perspectives, 2014; 5(5): 298-312.
  • Grover N, Patni V. Phytochemical characterization using various solvent extracts and GC MS analysis of methanolic extract of Woodfordia fruticosa (L.) KURZ. Leaves. Int J Pharm Pharm Sci, 2013; 5(4): 291-295.
  • Verma SK, Jain V, Katewa SS. Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum). Indian Journal of Biochemistry and Biophysics, 2009; 46(6): 503-506.
  • Khan A, Khan QJ, Gilani A. Pharmacological basis for the medicinal use of cardamom in asthma. Bangladesh J Pharmacol, 2011; 6: 34-37.
  • Ranasinghe P, Pigera S, Sirimal GA, Galappaththy PP, Constantine GR, Prasad K. Medicinal properties of ‗true‘cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complementary and Alternative Medicine, 2013; 13: 275.
  • Jayaprakasha GK, Rao LJ. Chemistry, biogenesis, and biological activities of Cinnamomum zeylanicum. Crit Rev Food Sci Nutr, 2011; 51: 547–562.
  • Lima ZP, Severi JA, Pellizzon CH, Brito AR, Solis PN. Gastroprotective activity of Cinnamomum tamala leaves on experimental gastric ulcers in rats, J. Ethnopharmacol. 2010; 128: 537-40.
  • Hemayet H, Howlader MSI, Dey SK, Hira A. Evaluation of antiinflammatory activity of Cinnamomum tamala (Buch.-Ham.) Leaves growing in Bangladesh, Int. J Pharmachol., 2012; 1(2):114-21.
  • Jamiuddin A, Sultana N, Dewan SMR, Amin MN, Uddin SMN. Determination of Chemical Groups and Investigation of Anthelmintic, Cytotoxic, and Antibacterial Activities of Leaves of Cinnamomum tamala (Family: Lauraceae), Int J Pharmamedix Ind., 2013; 1(2): 222-32
  • Ankurdeep Preety, Sandeep Sharma. A Brief Review on Cinnamomum tamala (Buch.-Ham.) Nees & Eberm.: An Important Medicinal Tree. International Journal of Research in Biological Sciences, 2016; 6(2): 26-31
  • Chahar K, Kumar SDS, Geetha L, Lokesh T, Manohara KP. Mesua ferrea L.: A review of the medical evidence for its phytochemistry and pharmacological actions. African Journal of Pharmacy and Pharmacology, 2013; 7(6): 211-219.
  • Alsaid M, Mothana R, Raish M, AlSohaibani M, Al-Yhya M, Ahmed A, Al-Dosari, Rafatullah S. Evaluation of the effectiveness of Piper cubeda extact in the amelioration of CCl4- induced liver injuries and oxidative stress in the rodent model. BioMed Res International, 2015: Article ID 359358, 11 pages. http://dx.doi.org/10.1155/2015/359358
  • Nahak G, Sahu RK. ―Phytochemical evaluation and antioxidant activity of Piper cubeba and Piper nigrum.‖ Journal of Applied Pharmaceutical Science, 2011; 1(8): 153–157, 2011.
  • Ahmad QZ, Jahan N, Ahmad G. ―Nephro-protective effect of Kabab chini (Piper cubeba) in gentamycin-induced nephrotoxicity. Saudi Journal of Kidney Diseases and Transplantation, 2012; 23(4):773–781
  • Shamkuwar PB, Shahi SR, Jadhav ST. Evaluation of antidiarrhoeal effect of Black pepper (Piper nigrum L.) Asian Journal of Plant Science and Research, 2012; 2(1): 48-53.
  • Meghwal M, Goswami TK. Chemical Composition, Nutritional, Medicinal and Functional Properties of Black Pepper: A Review. 1, 2012: 172. doi:10.4172/scientificreports.
  • Kumar S, Kamboj J, Sharma SS. Overview for Various Aspects of the Health Benefits of Piper Longum Linn. Fruit. J of Acupuncture and Meridian Studies. 2011; 4(2): 134-14.
  • Zadeh JL, Ko NM. Physiological and pharmaceutical effects of Ginger (Zingiber officinale Roscoe) as a valuable medicinal plant. European Journal of Experimental Biology, 2014; 4(1): 87-90.
  • Girish HV, Vinod AB, Dhananjaya LB, Sathish Kumar D, Duraisamy S. The Anticancer Potential of Pavonia odorata extract on Human Breast (MD-MB-231), Prostate (PC-3) and Lung (Calu-6) Cancer cell lines. Pharmacognosy Journal, 2018; 8(1):2830
  • Rajalakshmi P, Vadivel V, Subashini G, Pugalenthi M. Phytochemical screening and antioxidant activity of Mahonia leschenaultii wall. and Pavonia odorata willd leaves. International Journal of Advanced Research, 2016, 4(5): 1751-1757
  • R Hamidpour, S Hamidpour, M Hamidpour, M Shahlari. Camphor (Cinnamomum camphora), a traditional remedy with the history of treating several diseases. Int J of Case Reports and Images, 2013; 4(2): 86-89.
  • Hai Gu, Zequn Jiang, Mingyan Wang MD, Haiying Jiang, Fengming Zhao, Xia Ding, Baochang Cai, Zhen Zhan MD. 5Hydroxymethylfurfural from wine-processed Fructus corniinhibits hippocampal neuron apoptosis. Neural Regen Res. 2013; 8(28): 2605–2614.

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  • The GC MS Study of one Ayurvedic Medicine, Vasakadyaristam

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Authors

Muttevi Hyagreva Kumar
Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, India
K. Prabhu
Department of Anatomy, Sree Balaji Medical College and Hospital, Bharath University, Chrompet, Chennai - 600092, India
Mudiganti Ram Krishna Rao
Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai-600073, India
R. Lakshmi Sundaram
Central Research Facility, Sri Ramachandra Medical College and Research Institute, Purur, Chennai - 600116, India
Sampad Shil
Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai- 600073, India
S. Arun Kumar
Department of Industrial Biotechnology, Bharath Institute of Higher Education and Research, Chennai- 600073, India

Abstract


The present study deals with the GC MS analysis of one Ayurvedic prepaation, Vasakadyarishtam, which is a mucolytic medicine used for the treatment of cough, cold, chest congestion asthma and related diseases like bronchitis, inflammation and hemoptysis. The most important constituent of this medicine is Vasaka or Adhatoda vesika plant, which is known for its anti-cough and cold usage in Ayurveda. This study was to understand the main biomolecules present in this medicine by GC MS analysis. The results indicted the presence of some important molecules such as Eucalyptol, Phenylethyl alcohol, Camphor, Ethyl hydrogen succinate, Succinic acid, cyclobutyl ethyl ester, 3-Cyclohexen-1-ol,4-methyl-(1-methylethyl)-(R)-,. alpha.-Terineol, 5- Hydroxymethyl furfural, p-Anisic acid,4-nitrophenyl ester, 2-Propen-1-0l,3-phenyl, Benzeneethanol, 4-hydroxy- Propiophenone, 2‘-(trimethylsioxy)-, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester and Octadecanoic acid and 2,3 –dyhydroxypropyl ester. These molecules are known for their various medicinal properties which indicate their roles in this formulation.

Keywords


Vasakadyarishtam, Adhatoda vesika, Eucalyptol, Phenylethyl Alcohol, Camphor, Ethyl Hydrogen Succinate, Alpha.-Terineol.

References