Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Phytochemical Screening, Antimicrobial Activity and Antimicrobial Finishing of Polyherbal Extract on Nonwoven Wound Dressing


Affiliations
1 Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore, India
2 Department of Home Science, Mother Teresa Women’s University, Coimbatore, India
3 Department of Biochemistry, PSG College of Arts and Science, Coimbatore, India
     

   Subscribe/Renew Journal


Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected for the current study based on its potent antimicrobial activity. The poly herbal plant extract was tested against nine clinical bacterial strains that are responsible for the wound infections. The FTIR and GCMS studies of the poly herbal plant extract revealed the presence of functional groups such as phenols, alcohol, amines, carbonyl group and components responsible for antimicrobial properties respectively. The phytochemical analysis showed the presence of bioactive principles such as alkaloids, flavanoids, phenols, steroids and tannins. The poly herbal extract was then coated on the TencelR nonwoven fabric using pad-dry-cure method. The antimicrobial efficacy of the coated fabrics exhibited better inhibitory activity against all the test organisms under the standard AATCC 147. The coated fabric also showed 8 mm zone of inhibition against Candida albicans. The results recommend the use of poly herbal plant extract can potentially be used as a substitute to synthetic agents. Also, it can be employed in non-implantable medical textiles such as wound dressings to prevent the microbial infestation and also to reduce the bio burden in wound therapy.

Keywords

Antibacterial Susceptibility, Non-Implantable, Nonwoven, Wound Dressing, Wound Infections.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Uzun M, Anand S C, Shah T. J of Biomedical Engineering and Technology. 2013: 1 (1).

  • Heinrich Firgo, Christian Schuster K, Friedrich Suchomel, Johann Manner, Tom Burrowa, Mohammad Abu-Rousb. 2006:22 (85).

  • Sathianarayanan M P, Bhat N V, Kokate S S, Walnuj V E. Indian J of Fibre and Textile Research. 2010: 35 (50).

  • Bhuvanesh Gupta. Indian J of Fibre and Textile Research. 2010: 35 (174).

  • Stephen T Odonkor , Kennedy K Addo. Int J Biol Med Res. 2011: 2(4):1204.

  • Deepti Gupta, Ankur Laha. Indian J of Fibre and Textile Research. 2007: 88 (32).

  • Michael Bennett-Marsden. The Pharmaceutical Journal. 2010:1.

  • Parmar Namita, Rawat Mukesh. International Journal of Pharmacy. 2003:3(1): 31.

  • Abhishek. Textile Review magazine.2012.

  • Ramasamy Rajendran R, Balakumar C, Kalaivani J, Sivakumar R. J of Textile and Apparel, Technology and Management. 2011: 7(2).

  • Perez C, Pauli M, Bazerque P. Acta Biol Med Exp. 1990: 15(13): 115.

  • Pranay Jain, Rishabh Varshney. J. Chem. Pharm. Res. 2011: 3(3) : 260.

  • Nithya Devi P, Kaleeswari S, Poonkothai M. Int J of Pharmacy and Pharmaceutical Sciences. 2014: 6(5).

  • Chinta S.K, Landage S M, Abhishek , Sonawane K D and Jalkate C B. 2009.

  • R. Rajendran, Hasobo Mohammad Ahamed, R. Radhai, C. Balakumar. Proceedings. Int Conference on Nanostructures (ICNS4) Kish Island. I.R. Iran. 2012: 1 (1):75.

  • Rathinamoorthy R, Thilagavathi G. Int J of Pharmacy and Pharmaceutical Sciences. 2014: 6(2): 932.

  • Triveni S Inganakal, Udupi R H, Paramjyothi Swamy. Int J of Biological and Pharmaceutical Research. 2012: 3(5): 718.

  • Rajeshwari J, Rani S. Int J chemtech Research. 7(1): 389.

  • Ngassoum MB, Jirovetz L, Buchbauer G, Fleischhacker W. J. Ess. Oil Res. 2000: 12:345.

  • S.Gopalakrishnan. Int J of Pharma And Bio Sciences. 2011: 2(1): 314.

  • Sermakkani M, Thangapandian V. Asian J of Pharmaceutical and Clinical Research. 2012: 5(2) :90.

  • Selvamangai G, Anusha Bhaskar. Asian Pacific J of Tropical Biomedicine. 2012: S1329.

  • Arockia Jenecius, Veerabahu Ramasamy Mohan. World J of Pharmacy and Pharmaceutical Sciences. 3(4): 1044.

  • Eugin Amala V, Jeyaraj M. Int J of Pharma and Bio Sciences. 5(4): 927.

  • Deepti Gupta, Ankur Laha. Indian J of Fibre and Textile Research. 2007: 32(88).

  • Thilagavathi G, Rajendrakumar K, Rajendran R. Indian J of Fibre and Textile Research. 2005:30: 431.


Abstract Views: 170

PDF Views: 0




  • Phytochemical Screening, Antimicrobial Activity and Antimicrobial Finishing of Polyherbal Extract on Nonwoven Wound Dressing

Abstract Views: 170  |  PDF Views: 0

Authors

P. Karpagam
Department of Costume Design and Fashion, PSG College of Arts and Science, Coimbatore, India
G. Manonmani
Department of Home Science, Mother Teresa Women’s University, Coimbatore, India
D. Brindha
Department of Biochemistry, PSG College of Arts and Science, Coimbatore, India

Abstract


Terminalia bellerica, Withania somnifera, Madhuca longifolia and Sygyzium cumini was selected for the current study based on its potent antimicrobial activity. The poly herbal plant extract was tested against nine clinical bacterial strains that are responsible for the wound infections. The FTIR and GCMS studies of the poly herbal plant extract revealed the presence of functional groups such as phenols, alcohol, amines, carbonyl group and components responsible for antimicrobial properties respectively. The phytochemical analysis showed the presence of bioactive principles such as alkaloids, flavanoids, phenols, steroids and tannins. The poly herbal extract was then coated on the TencelR nonwoven fabric using pad-dry-cure method. The antimicrobial efficacy of the coated fabrics exhibited better inhibitory activity against all the test organisms under the standard AATCC 147. The coated fabric also showed 8 mm zone of inhibition against Candida albicans. The results recommend the use of poly herbal plant extract can potentially be used as a substitute to synthetic agents. Also, it can be employed in non-implantable medical textiles such as wound dressings to prevent the microbial infestation and also to reduce the bio burden in wound therapy.

Keywords


Antibacterial Susceptibility, Non-Implantable, Nonwoven, Wound Dressing, Wound Infections.

References