Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Prognosis of Long-Term Postoperative Complications after Surgical Treatment of Dupuytren’s Disease (Contracture)


Affiliations
1 Department of Traumatology, City Clinical Hospital No 7 of Kazan, Kazan, Republic of Tatarstan, Russian Federation
2 Department of Biochemistry, Kazan State Medical University, Kazan, Republic of Tatarstan, Russian Federation
3 Republican Clinical Hospital of Tatarstan Republic Health Ministry, Kazan, Republic of Tatarstan, Russian Federation
4 4Department of Management in the Social Sphere, Kazan Federal University, Kazan, Republic of Tatarstan, Russian Federation
     

   Subscribe/Renew Journal


Background Dupuytren’s disease (DD) is a proliferative fibromatosis of the hand, which causes permanent flexion contracture of the digits and, ultimately, loss of function. The treatment of DD is complex and involves surgical and nonsurgical approaches, with the goal of removing the affected tissue. Systems analysis of postoperative complications depending on combination of factors of the patient and influencing development of long-term postoperative complications (LPC) is the way which can optimize tactics of surgical treatment. Purpose To develop prognosis of long-term postoperative complications’ technology after surgical treatment of Dupuytren’s disease (contracture) on the basis of the analysis of A-factors, determining the biological status of the patient ( gender, age, terms of disease, examination period, grade of lesion by DD, heredity, accompanying diseases, surgical history and traumas, the disease beginning, laboratory analyses, etc.); B-factors, presenting life style of the patient (residence, physical and mental job, bad habits, etc.); C-factors, presenting technical-surgical components of operations and rehabilitational treatment (the experience of the surgeon, types of operations, anaesthesia, section, dermal plasty, rehabilitational treatment, healing, etc.). Methods Anamnesis, operative measures, postoperative catamnesis, mathematical modeling. Results Technology allows to prognosticate the operation outcome in 58,9–81,4% of cases. This depends on type of considered factors (a combination of factors,% of prognosticated cases): 1. A + B + C 72,8–78,7% (р=0,0001) 2. А+В 64,4–73,3% (р=0,0001); 3. C 58,9–81,4% (р ≤ 0,002). Conclusions Anamnesis, the analysis of technique of operative measures and rehabilitational treatment allow to predict the outcome of operative treatment concerning DD. Increasing (27 factors) and decreasing (12 factors) of LPC are the outstanding points for development prognosis of LPC.

Keywords

Complications, Dupuytren’s Contracture, Prognosis, Surgery.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Badois FJ, Lermusiaux JL, Masse AC and Kuntz D. Nonsurgical treatment of Dupuytren’s disease using needle fasciotomy. Rev. Rhum. Ed. Engl. 60; 1993: 692-697.

  • Lermusiaux JL, Lellouche H, Badois JF and Kuntz D. How should Dupuytren's contracture be managed in 1997? Rev. Rhum. Ed. Engl. 64(12); 1997: 775-776.

  • Kelly AP Jr and Clifford RH. Subcutaneous fasciotomy in the treatment of Dupuytren's contracture. Plast. Reconstr. Surg. Transplant Bull. 24; 1959: 505-510.

  • Luck JV. Dupuytren's contracture. A new concept of the pathogenesis correlated with surgical management. J Bone Joint Surg Am. 41-A(4); 1959: 635-664.

  • Moermans JP. Segmental aponeurectomy in Dupuytren's disease. J. Hand Surg. Br. 16(3); 1991: 243-254.

  • Moermans JP. Long-term results after segmental aponeurectomy for Dupuytren's disease. J. Hand Surg. Br. 21(6); 1996: 797-800.

  • Chick LR and Lister GD. Surgical alternatives in Dupuytren's contracture. Hand. Clin. 7(4); 1991: 715-719.

  • Lubahn JD and Lister GD, Wolfe T. Fasciectomy and Dupuytren's disease: a comparison between the open-palm technique and wound closure. J. Hand Surg. Am. 9A(1); 1984: 53-58.

  • Maravic M and Landais P. Dupuytren's disease in France-1831 to 2001-from description to economic burden. J. Hand Surg. Br. 30(5); 2005: 484-487.

  • McCash CR. The open palm technique in Dupuytren's contracture. Br. J. Plast. Surg. 17; 1964: 271-280.

  • Hueston JT. Recurrent Dupuytren's contracture. Plast. Reconstr. Surg. 31; 1963: 66-69.

  • McIndоe AH and Beare RL. The surgical management of Dupuytren's contracture. Am. J. Surg. 95(2); 1958: 197-203.

  • Foucher G, Cornil A C, Lenoble E and Citron N. A modified open palm technique for Dupuytren’s disease. Short and long term results in 54 patients. Int. Orthop. 19(5); 1995: 285-258.

  • Citron ND and Nunez V. Recurrence after surgery for Dupuytren’s disease a randomized trial of two skin incisions. J. Hand. Surg. Br. 30(6); 2005: 563-566.

  • van Rijssen AL and Werkr PM. Percutaneous needle fasciotomy in Dupuytren’s disease. J. Hand Surg. Br. 31(5); 2006: 498-501.

  • Wilbrand S, Flodmark AC, Ekbom A and Gerdin B. Activation markers of connective tissue in Dupuytren’s contracture: relation to postoperative outcome. Scand. J. Plast. Reconstr. Surg. Hand Surg. 37(5); 2003: 283-292.

  • Crean SM, Gerber RA, Hellio Le Graverand MP, Boyd DM and Cappelleri JC. The efficacy and safety of fasciectomy and fasciotomy for Dupuytren's contracture in European patients: a structured review of published studies. J. Hand Surg. Eur. 36(5); 2011: 396-407.

  • Mikusev GI, Magomedov RO, Osmonaliev I, Baikeev RF and Mikusev IE. Dupuytren's contracture: epidemiology, etiology, pathogenesis, diagnozis and treatment. Kazan Medical Journal. 92(6); 2001: 896-900.

  • Henry W and Meyerding MD. Dupuytren's contracture. Arch. Surg. 32(2); 1936: 320-333.

  • Iselin M and Iselin F. Maladie de Duputren. Traité de Chirugie de la Main. Flammarion, Brussels. 1967.

  • Tubiana R. Evaluation of deformities in Dupuytren's disease. Annales de Chirurgie de la Main. 5(1); 1986: 5-11.

  • Brenner P. Dupuytren-kontraktur. In: Berger A. (ed.). Plastische chirurgie – handchirurgie. Breitnersche Operationslehre. XIV. München Wien Baltimore, Urban AND Schwarzenberg. 1997; pp. 13-27.

  • Hueston JT. Limited fasciectomy for Dupuytren's contracture. Plast. Reconstr. Surg. 27; 1961: 569-585.

  • Dabrowski T. Treatment of Dupuytren's contracture by excision of the base of the palmar aponeurosis. Acta Med. Pol. 8(4); 1967: 499-504.

  • Мikusev GI., Baykeev RF, Mikusev IE and Magomedov RO. Dupuytren’s disease. The register of ТR. Bulletin of Traumatology and Orthopedy of N.N. Priorov. 4; 2007: 65-69.

  • Becker K, Tinschert S, Lienert A, Bleuler PE, Staub F, Meinel A, Rößler J, Wach W, Hoffmann R, Kühnel F, Damert HG, Nick HE, Spicher R, Lenze W, Langer M, Nürnberg P and Hennies HC. The importance of genetic susceptibility in Dupuytren's disease. Clin. Genet. 87(5); 2015: 483-487.

  • Ten Dam EP, van Beuge MM, Bank RA and Werker PM. Further evidence of the involvement of the Wntsignalling pathway in Dupuytren's disease. J Cell Commun Signal. 10(1); 2016: 33-40.

  • World Health Organization. International statistical classification of diseases and related health problems. 2010. Available from: URL: http://www.who.int/classifications/icd/ICD10Volume2_en_2010.pdf

  • Smith P and Breed AC. Central slip attenuation in Dupuytren’s contracture: a cause of persistent flexion of the proximal interphalangeal joint. J. Hand Surg. Am. 19(5); 1994: 840-843.

  • Tripoli M and Merle M. The "Jacobsen Flap" for the treatment of stages III-IV Dupuytren's disease: a review of 98 cases. J. Hand Surg. Eur. 33(6); 2008: 779-782.

  • Coert JH, Nerin JP and Meek MF. Results of partial fasciectomy for Dupuytren’s disease in 261 consecutive patients. Ann. Plast. Surg. 57(1); 2006: 13-17.

  • Foucher G, Cornil AC and Lenoble E. Open plam technique for Dupuytren’s disease. Postoperative complications and results after more than 5 years. Chirurgie. 118(4); 1992: 189-194.

  • Foucher G, Cornil AC and Lenoble E. Open palm technique for Dupuytren’s disease. A five-year followup. Ann. Chir. Main Memb. Super. 11(5); 1992: 362-366.

  • Kjeldal I and Nygaard HP. Out-patient surgery for Dupuytren’s disease under intravenous regional anaesthesia. J. Hand Surg. Br. 13(3); 1988: 257-258.

  • Macnicol MF. The open palm technique for Dupuytren's contracture. Int. Orthop. 8(1); 1984: 55-89.

  • Constantinou E and Deutinger M. Results after surgical treatment of Dupuytren’s contracture. Acta Chirurgica Austriaca. 28; 1996: 163-165.

  • Foucher G, Medina J and Navarro R. Percutaneous needle aponeurotomy: complications and results. J. Hand Surg. Br. 28(5); 2003: 427-431.

  • Makela EA, Jaroma H, Harju A, Anttila S and Vainio J. Dupuytren's contracture: the long-term results after day surgery. J. Hand Surg. Br. 16(3); 1991: 272-274.

  • Foucher G, Shuind F and Lemarechal P. The open palm technique in the management of Dupuytren’s contracture. Ann. Chir. Plast. Esthet. 30; 1985: 211-215.

  • Hogemann A, Wolfhard U, Kendoff D, Board TN and Olivier LC. Results of total aponeurectomy for Dupuytren’s contracture in 61 patients: a retrospective clinical study. Arch. Orthop. Trauma Surg. 129(2); 2009: 195-201.

  • Armstrong JR, Hurren JS and Logan AM. Dermofasciectomy in the management of Dupuytren's disease. J. Bone. Joint. Surg. Br. 82(1); 2000: 90-94.

  • Tonkin MA, Burke FD and Varian JP. Dupuytren's contracture: a comparative study of fasciectomy and dermofasciectomy in one hundred patients. J. Hand Surg. Br. 9(2); 1984: 156-162.

  • Bulstrode NW, Jemec B and Smith PJ. The complications of Dupuytren's contracture surgery. J. Hand Surg. Am. 30(5); 2005: 1021-1025.

  • Nieminen S and Lehto M. Resection of the palmarislongus tendon in surgery for Dupuytren's contracture. Ann. Chir. Gynaecol. 75(3); 1986: 164-167.

  • Moermans JP. Recurrences after surgery for Dupuytren's disease. Eur. J. Plastic. Surg. 20(5); 1997: 240-245.

  • Roy N, Sharma D, Mirza AH, Fahmy N., Fasciectomy and conservative full thickness skin grafting in Dupuytren’s contracture. The fish technique. ActaOrthop. Belg., 72(6); 2006: 678-682.

  • Ullah AS, Dias JJ and Bhrowal B. (Does a "firebreak" full-thickness skin graft prevent recurrence after surgery for Dupuytren’s contracture?: A prospective, randomized trial. J. Bone Joint Surg. Br. 91(3); 2009: 374-378.

  • Norotte G, Apoil A and Travers V. A ten years follow-up of the results of surgery for Dupuytren’s disease. A study of fifty-eight cases. Ann. Chir. Main. 7(4); 1988: 277-281.

  • Lee H. The Lived Experience of Clinical Nurse Specialist: A Phenomenological Study. Research Journal of Pharmacy and Technology. 11(3); 2018: 857-862.


Abstract Views: 226

PDF Views: 0




  • Prognosis of Long-Term Postoperative Complications after Surgical Treatment of Dupuytren’s Disease (Contracture)

Abstract Views: 226  |  PDF Views: 0

Authors

Gleb I. Mikusev
Department of Traumatology, City Clinical Hospital No 7 of Kazan, Kazan, Republic of Tatarstan, Russian Federation
Rustem F. Baikeev
Department of Biochemistry, Kazan State Medical University, Kazan, Republic of Tatarstan, Russian Federation
Ruslan O. Magomedov
Republican Clinical Hospital of Tatarstan Republic Health Ministry, Kazan, Republic of Tatarstan, Russian Federation
Ivan E. Mikusev
Republican Clinical Hospital of Tatarstan Republic Health Ministry, Kazan, Republic of Tatarstan, Russian Federation
Timur S. Mishakin
4Department of Management in the Social Sphere, Kazan Federal University, Kazan, Republic of Tatarstan, Russian Federation

Abstract


Background Dupuytren’s disease (DD) is a proliferative fibromatosis of the hand, which causes permanent flexion contracture of the digits and, ultimately, loss of function. The treatment of DD is complex and involves surgical and nonsurgical approaches, with the goal of removing the affected tissue. Systems analysis of postoperative complications depending on combination of factors of the patient and influencing development of long-term postoperative complications (LPC) is the way which can optimize tactics of surgical treatment. Purpose To develop prognosis of long-term postoperative complications’ technology after surgical treatment of Dupuytren’s disease (contracture) on the basis of the analysis of A-factors, determining the biological status of the patient ( gender, age, terms of disease, examination period, grade of lesion by DD, heredity, accompanying diseases, surgical history and traumas, the disease beginning, laboratory analyses, etc.); B-factors, presenting life style of the patient (residence, physical and mental job, bad habits, etc.); C-factors, presenting technical-surgical components of operations and rehabilitational treatment (the experience of the surgeon, types of operations, anaesthesia, section, dermal plasty, rehabilitational treatment, healing, etc.). Methods Anamnesis, operative measures, postoperative catamnesis, mathematical modeling. Results Technology allows to prognosticate the operation outcome in 58,9–81,4% of cases. This depends on type of considered factors (a combination of factors,% of prognosticated cases): 1. A + B + C 72,8–78,7% (р=0,0001) 2. А+В 64,4–73,3% (р=0,0001); 3. C 58,9–81,4% (р ≤ 0,002). Conclusions Anamnesis, the analysis of technique of operative measures and rehabilitational treatment allow to predict the outcome of operative treatment concerning DD. Increasing (27 factors) and decreasing (12 factors) of LPC are the outstanding points for development prognosis of LPC.

Keywords


Complications, Dupuytren’s Contracture, Prognosis, Surgery.

References