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Pharmacological Evaluation of Leaf Extract of Terminalia bellerica with Moringa oleifera for its Synergistic Action on Anti-diabetic Activity and Anti-inflammatory Activity in Rats


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1 Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh, India
     

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Aim and Objective: To evaluate the pharmacological action of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on Anti Diabetic activity and Anti-inflammatory activity in rats. Methodology: The Pharmacological evaluation of standardized aqueous extract of the leaves of Terminalia bellerica with Moringa oleifera was carried by using the following Stimuli models: a)Antidiabetic activity by Streptozotocin Induced Diabetes, b) Anti-inflammatory activity by Egg Albumin Induced Paw Edema. Results: The parameters of various activities to assess anti diabetic and anti inflammatory activities were evaluated and found That, The combination of extracts possess a better response then alone. Conclusion: The aqueous leaf extract of the combination of Terminalia bellerica with Moringa oleifera has shown significant anti diabetic and anti-inflammatory activities when compared with standard and extract alone.

Keywords

Terminalia bellerica, Moringa oleifera, Anti Diabetic Activity, Anti-Inflammatory Activity, Digital Plethysmometer, Glucometer.
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  • Pharmacological Evaluation of Leaf Extract of Terminalia bellerica with Moringa oleifera for its Synergistic Action on Anti-diabetic Activity and Anti-inflammatory Activity in Rats

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Authors

Sk. Karishma
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh, India
K. Lakshmi
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh, India
D. Eswar Tony
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh, India
A. Narendra Babu
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh, India
Rama Rao Nadendla
Department of Pharmacology, Chalapathi Institute of Pharmaceutical Sciences, Guntur. Andhra Pradesh, India

Abstract


Aim and Objective: To evaluate the pharmacological action of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on Anti Diabetic activity and Anti-inflammatory activity in rats. Methodology: The Pharmacological evaluation of standardized aqueous extract of the leaves of Terminalia bellerica with Moringa oleifera was carried by using the following Stimuli models: a)Antidiabetic activity by Streptozotocin Induced Diabetes, b) Anti-inflammatory activity by Egg Albumin Induced Paw Edema. Results: The parameters of various activities to assess anti diabetic and anti inflammatory activities were evaluated and found That, The combination of extracts possess a better response then alone. Conclusion: The aqueous leaf extract of the combination of Terminalia bellerica with Moringa oleifera has shown significant anti diabetic and anti-inflammatory activities when compared with standard and extract alone.

Keywords


Terminalia bellerica, Moringa oleifera, Anti Diabetic Activity, Anti-Inflammatory Activity, Digital Plethysmometer, Glucometer.

References