Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Study on Drug Utilization Pattern of Antibiotics in Respiratory Tract Infections


Affiliations
1 Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (Nitte Deemed to be University), Derlakatte, Mangaluru, India
2 Department of ENT, Justice K.S. Hegde Hospital, Mangaluru, India
     

   Subscribe/Renew Journal


Objective: The aim of the study is to analyse the drug utilization pattern of antibiotics in patients with respiratory tract infections (RTIs). Methods: A prospective observational study was conducted for a period of 8 months. The prescriptions were followed on daily basis and the prescribing frequency of various antibiotics were categorized and documented. As per the WHO-ATC system the consumption of antibiotics was determined by DDD/100 bed days. Results: Out of 136 patients, 70(51.5%) were males and 66 (48.5%) were females. Majority of patients were in the age group of 18-29 years. The most common RTIs among the patients was found to be otitis media (61%), followed by sinusitis (14.7%). Majority of the patients were prescribed with cephalosporin which includes ceftriaxone (52.2%) and cefixime (37.5%). Pseudomonas aeroginosa and staphylococcus were the most isolated organisms. Pseudomonas aeroginosa shows maximum sensitivity to ciprofloxacin, ceftazidime and staphylococcus aureus towards gentamicin and erythromycin. Conclusion: Otitis media and sinusitis were the commonly found respiratory infections and are frequently managed by cephalosporins. The study also established the consumption of various antibiotics used in the management of respiratory tract infections.

Keywords

Antibiotic, Respiratory Tract Infections, Drug Utilization.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Pallavi I, Roshani S, Amita S, Prabhakar S. , Prescribe Pattern of drugs and antimicrobials preferences in the Department of ENT at tertiary care SGM Hospital, Rewa, MP. , India. J Pharm Biomed Sci. , 2016; 6(1):89-93.

  • Patil L, Khairnar A.,Ninety percent drug utilization in patients of upper respiratory infections., Int. Res. J. Pharm., 2013;4(6):189-93.

  • Jose S, Rajashekarachar Y, Basavanthappa SP, Naidu BR., Evaluation of antibiotic usage on lower respiratory tract infections in paediatric department-an observational study., International Journal of Contemporary Pediatrics., 2016;3(1):146-9.

  • Mahajan HM, Date AP, Badwaik RT, Borkar AS, Wanmali SS, Gohad GV., Analysis of pattern of antimicrobial use in RTIs in a tertiary care hospital of central india-A drug utilization study., J Cont Med A Dent., 2014;2(3):59-64.

  • Kancherla D, Satya Sai MV, Gayathri Devi HJ and Sharma S., A Study on prescribing pattern of antibiotics in respiratory tract infection in a tertiary care center., International. Journal of Recent Scientific Research., 2015; 6(6): 4558-63. 3.

  • Naik HG, Khanwelkar CC, Kolur A, Desai A, Gidamudi S., Drug Utilization Study on Antibiotics use in Upper Respiratory Tract Infection., International Journal of Recent Trends in Science and Technology., 2014;10(2):299-302.

  • Choudhury DK, Bezbaruah BK., Antibiotic Prescriptions Pattern in Paediatric In-Patient Department Gauhati Medical College and Hospital, Guwahati., J App Pharm Sci., 2013;3(08):144-8.

  • Pradhan S, Jauhari AC., A study of antibiotics used in adult respiratory disorders in Kathmandu and Bhaktapur., Nepal Med Coll J., 2007;9:120-4.

  • Errabelly P, Ramavath V, Afreen A, Sanaboina A., Analysis of the prescribing patterns of antibiotics in respiratory tract infections at department of medicine at a tertiary care hospital., International Journal of Pharmaceutical Sciences and Research., 2015;6(7): 2963-2967.

  • Gogoi S, Saikia PP., A study on prescribing pattern of antibiotics for upper respiratory tract infections by general practitioners in rural areas of Assam., IJSR., 2015;4(5):60-2.

  • Sridevi SA, Janagan T, Rathnasamy P., Rajarajeswari R., Drug utilization study in the otorhinolaryngology department in a tertiary care hospital., Int J Basic Clin Pharmacol., 2013;2(3):306-10.

  • WHO Collaborating Centre for Drug Statistics Methodology. Guidelines for ATC classification and DDD assignment. 20th edi. Oslo (Norway): World Health organization 2017; 15-30.

  • Suman RK, Kumar R, Mohanty IR, Deshmukh YA., Assessment of drug usage pattern of antibiotics used in ENT OPD of tertiary care teaching hospital., Int J Health Sci Res., 2015;5(9):290-7.

  • Ghosh A, Das AK, Gure PK, Pati S., An observationa; study of drug use in upper respiratory tract infection in patients attending ENT outpatient department in a tertiary care hospital in kolkota., Asian journal of pharmaceutical and clinical research., 2015;8(4): 37-40.

  • Shankar PR, Subish P, Upadhyay D, Dubey AK, Deshpande VY. Cephalosporin utilization in the inpatient wards of a teaching hospital in western Nepal. Journal of Institute of Medicine. 2005; 27: 7-12.

  • Shankar RP, Partha P, Shenoy NK, Easow JM, Brahmadathan KN. Prescribing patterns of antibiotics and sensitivity patterns of common microorganisms in the Internal Medicine ward of a teaching hospital in Western Nepal: a prospective study. Annals of Clinical Microbiology and Antimicrobials. 2003.


Abstract Views: 242

PDF Views: 0




  • Study on Drug Utilization Pattern of Antibiotics in Respiratory Tract Infections

Abstract Views: 242  |  PDF Views: 0

Authors

Shafinaz
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (Nitte Deemed to be University), Derlakatte, Mangaluru, India
Juno J. Joel
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (Nitte Deemed to be University), Derlakatte, Mangaluru, India
Vadish S. Bhat
Department of ENT, Justice K.S. Hegde Hospital, Mangaluru, India
E. R. Angel Rose
Department of Pharmacy Practice, NGSM Institute of Pharmaceutical Sciences (Nitte Deemed to be University), Derlakatte, Mangaluru, India

Abstract


Objective: The aim of the study is to analyse the drug utilization pattern of antibiotics in patients with respiratory tract infections (RTIs). Methods: A prospective observational study was conducted for a period of 8 months. The prescriptions were followed on daily basis and the prescribing frequency of various antibiotics were categorized and documented. As per the WHO-ATC system the consumption of antibiotics was determined by DDD/100 bed days. Results: Out of 136 patients, 70(51.5%) were males and 66 (48.5%) were females. Majority of patients were in the age group of 18-29 years. The most common RTIs among the patients was found to be otitis media (61%), followed by sinusitis (14.7%). Majority of the patients were prescribed with cephalosporin which includes ceftriaxone (52.2%) and cefixime (37.5%). Pseudomonas aeroginosa and staphylococcus were the most isolated organisms. Pseudomonas aeroginosa shows maximum sensitivity to ciprofloxacin, ceftazidime and staphylococcus aureus towards gentamicin and erythromycin. Conclusion: Otitis media and sinusitis were the commonly found respiratory infections and are frequently managed by cephalosporins. The study also established the consumption of various antibiotics used in the management of respiratory tract infections.

Keywords


Antibiotic, Respiratory Tract Infections, Drug Utilization.

References