Research Journal of Pharmacy and Technology

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Diabmag:A Better, Safe and Compatible Sugar Alternate


Affiliations
1 Pharmacy Dept., PSIT, Kanpur, India
     

   Subscribe/Renew Journal


AIM: To evaluate the features of plant based Diabmag sugar alternate. OBJECTIVE: To analyze Diabmag, herbal based sweetener on various parameters. MATERIALS AND METHODS:120 subjects were randomly selected, at a health camp held at a renowned park at Kanpur. A questionnaire was asked to be completed by the participants that included questions about various aspects of Diabmag formulation. RESULTS: Taste, intensity, practicality and after taste were analyzed on the basis of results of questionnaire. CONCLUSION: Diabmag is a safe, efficient and compatible sugar alternate.

Keywords

Diabmag, Questionnaire, Sugar, Safe, Alternate.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Nutritional Recommendations for Individuals with Diabetes Alison Gray, RD, MBA Senior Clinical Research Scientist, Lilly USA LLC; DC 2231 : May 31, 2015.

  • Lange FT, Scheurer M, Brauch HJ. Artificial sweeteners – A recently recognized class of emerging environmental contaminants: A review. Anal Bioanal Chem. 2012;403:2503–18. [PubMed].

  • Shankar P, Ahuja S, Sriram K. Non-nutritive sweeteners: Review and update. Nutrition. 2013;29:1293-9.

  • Sylvetsky A, Welsh J, Brown R, Vos M. Low-calorie sweetener consumption is increasing in the United States. Am J ClinNutr. 2012;96:640-6.

  • Gupta S, Mahajan V, Mahajan, S, et al. Artificial sweeteners. JK Sci. 2012;14:2-4.

  • De Vriese AS, Verbeuren TJ, Van de Voorde J, Lameire NH, Vanhoutte PM (2000) Endothelial dysfunction in diabetes. Br J Pharmacol 130: 963-974.

  • O'Driscoll G, Green D, Rankin J, Stanton K, Taylor R (2014) Improvement in Endothelial Function by Angiotensin Converting Enzyme Inhibition in Insulin-dependent Diabetes Mellitus. The Journal of Clinical Investigation 678-684.

  • Mazur RH, Goldkamp AH, James PA, Schlatter JM. Structure-taste relationships of aspartic acid amides. J Med Chem. 1970;6:1217–1221. doi: 10.1021/jm00300a046. [PubMed].

  • George V, Arora S, Wadhwa BK, Singh AK. Analysis of multiple sweeteners and their degradation products in lassi by HPLC and HPTLC plates. J Food Sci Technol. 2010;47:408–413. doi: 10.1007/s13197-010-0067-4. [PMC free article] [PubMed].

  • Trocho C, Pardo R, Rafecas I, Virgili JX, Remesar X, Fernandez-Lopez JA, Alemany M. Formaldehyde derived from dietary aspartame binds to tissue components in vivo. Life Sci. 1998;63:337–349. doi: 10.1016/S0024-3205(98)00282-3. [PubMed].

  • Reports of the meetings on Aspartame with national experts. ON-1641 Noted at the 36th Advisory Forum Meeting. 2010. May 19-20, [Last accessed on 2011 June 8]. Available from: http://www.efsa.europa.eu/en/supporting/doc/1641.pdf .

  • Simintzi I, Schlupis KH, Angelogianni P, Liapi C, Tsakiris S. The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study. Food Chem Toxicol. 2007;45:2397–401. [PubMed]

  • Christian B, Mc Connaughey K, Bethea E, Brantley S, Coffey A, Hammond L, et al. Chronic aspartame affects T-maze performance, brain cholinergic receptors and Na+, K+-ATPase in rats. Pharmacol Biochem Behav. 2004;78:121–7. [PubMed]

  • Tutelyan VA, Kravchenko LV, Kuzmina EE. The effect of aspartame on the activity of rat liver xenobiotic-metabolizing enzymes. Drug metabolism and Disposition: Drug Metab Dispos. 1990;18:223–5. [PubMed]

  • New Study of Splenda (Sucralose) Reveals Shocking Information About Potential Harmful Effects, cited from Dr. Mercola's Natural Health Newsletter, available at https://articles.mercola.com/sites/articles/archive/2009/02/10/

  • 7 Sucralose side effects, cited from Healthy focus available at https://healthyfocus.org/7-sucralose-side-effects/

  • Brown R, Banate M, and Rother K. Artificial Sweeteners: A systematic review of metabolic effects in youth. Int J PediatrObes. 2010; 5(4): 305–12.

  • Sugar substitute, cited from From Wikipedia, the free encyclopedia, available on https://en.wikipedia.org/wiki/Sugar_substitute.

  • Bellisle F, Drewnowski A. Intense sweeteners, energy intake and the control of body weight. Eur J ClinNutr. 2007;61:691–700.

  • Wang Z, Xue L, Guo C, et al. Stevioside ameliorates highfat diet-induced insulin resistance and adipose tissue inflammation by downregulating the NF-kappa B pathway. Biochem Biophys Res Commun. 2012;417:1280-5.

  • Shivanna N, Naika M, Khanum F, et al. Antioxidant, antidiabetic and renal protective properties of Stevia rebaudiana. J Diabetes Complications. 2013;27:103-13.

  • Lailerd N, Saengsirisuwan V, Sloniger J, et al. Effects of stevioside on glucose transport activity in insulin-sensitive and insulin-resistant rat skeletal muscle. Metab Clin Exp.2004;53:101-7.

  • Rizzo B, Zambonin L, Angeloni C, et al. Steviol glycosides modulate glucose transport in different cell types. Oxid Med Cell Longev. 2013;2013:348169.

  • Marcinek K, Krejpcio Z (2015) Stevia rebaudianabertoni—chemical composition and functional properties. ActaSci Pol Technol Aliment 14:145–152Google Scholar

  • Raymond KW (2010) General Organic and Biological Chemistry Vol 516. John Wiley and Sons, USA, pp 364–368Google Scholar

  • Kulthe AA et al (2014) Development of high protein and low calorie cookies. J Food Sci Technol 51:153–157CrossRefGoogle Scholar

  • Glycyrrhizin cited from Sugar and sweetener guide available from http://www.sugar-and-sweetener-guide.com/glycyrrhizin.html.

  • Garcia-Serna E et al (2014) Use of coffee silverskin and stevia to improve the formulation of shortbread. Pol J Food Nutr Sci 64:243–251Google Scholar

  • Delgado-Andrade C, Rufián-Henares JA, Morales FJ (2009) Hydroxymethyl furfural in commercial shortbread marketed in Spain. J Food Nutr Res 48:14–19


Abstract Views: 179

PDF Views: 0




  • Diabmag:A Better, Safe and Compatible Sugar Alternate

Abstract Views: 179  |  PDF Views: 0

Authors

Pranay Wal
Pharmacy Dept., PSIT, Kanpur, India
Rashmi Saxena Pal
Pharmacy Dept., PSIT, Kanpur, India
Ankita Wal
Pharmacy Dept., PSIT, Kanpur, India
Yogendra Pal
Pharmacy Dept., PSIT, Kanpur, India

Abstract


AIM: To evaluate the features of plant based Diabmag sugar alternate. OBJECTIVE: To analyze Diabmag, herbal based sweetener on various parameters. MATERIALS AND METHODS:120 subjects were randomly selected, at a health camp held at a renowned park at Kanpur. A questionnaire was asked to be completed by the participants that included questions about various aspects of Diabmag formulation. RESULTS: Taste, intensity, practicality and after taste were analyzed on the basis of results of questionnaire. CONCLUSION: Diabmag is a safe, efficient and compatible sugar alternate.

Keywords


Diabmag, Questionnaire, Sugar, Safe, Alternate.

References