Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Phytochemical and Pharmacognostical Evaluation of Milky Mangrove Excoecaria agallocha Linn


Affiliations
1 Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018. (MS), India
2 Marathwada Mitra Mandal's College of Pharmacy, Thergaon, Pune – 411033. (MS), India
     

   Subscribe/Renew Journal


Background: Excoecaria agallocha Linn. (Euphorbiaceae) is a small mangrove tree that grows widely in the tidal forests and coastal areas of India. Milky Mangrove is known to have antihyperglycemic, antimicrobial, anti-inflammatory and many other bioactivities. Aim: The present work aims to perform a comprehensive phytochemical and pharmacognostical study of Excoecaria agallocha Linn. Materials and Methods: The Pharmacognostical studies on Excoecaria agallocha including parameters such as morphological evaluation, microscopical evaluation, leaf constants, physicochemical parameters, Thin layer chromatography (TLC) and phytochemical studies were established. Result and Conclusion: Mean ash values (%) were 16.00 (total), 2.75 (acid insoluble), and 13.35 (water soluble). Loss on drying was 0.20%. Microscopy reveals dorsiventral leaf and presence of diacytic stomata in the leaf sample. Quantitative microscopical features such as Stomatal Index, Vein islet number, vein termination number and palisade ratio was determined. The report of TLC indicates presence of Alkaloids and flavonoids. Phytochemical study revealed the presence of alkaloids, steroids, flavonoids, terpenes, tannins and phenolic compounds. Conclusion: The results of the study can serve as a valuable resource of pharmacognostic and phytochemical information. Further work is needed to isolate, characterize, and quantify active constituents present in the leaves of Excoecaria agallocha Linn. by sophisticated techniques.

Keywords

Excoecaria agallocha Linn., Pharmacognostic Evaluation, Phytochemical Evaluation, Thin Layer Chromatography.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Agrawal O. P., Jain S. K., Sharma P., International Journal of Green Pharmacy, octdec.2017 11(4), 1-5.
  • Annonymous., The Wealth of India, A Dictionary of Indian Raw Materials and Industrial Products, New Delhi, 2002, D-E, III, 234.
  • Bulani V, Biyani K, Kale R et al. Inhibitory effect of Calotropis gigantea extract on Ovalbumin-induced airway inflammation and Arachidonic acid induced inflammation in a murine model of asthma. International Journal of Current Biological and Medical Science. 2011; 1(2):19-25.
  • Agoramoorthy G, Chen F, Venkatesalu V, Kuo D, Shea P, Evaluation of Antioxidant Polyphenols from Selected Mangrove Plants of India., Asian Journal of Chemistry; 2002, 1311-1322.
  • Yadav V.K., Irchhiya R., Ghosh A.K., Phytochemical and Pharmacognostic study, International Journal of Green Pharmacy, Jan-March 2018, 12(1), 1-9.
  • Khandelwal K. R., Techniques and Experiments, Practical Pharmacognosy, Nirali Prakashan, 27th Edition, 2016, 11.1-11.8 and 24.1-24.4.
  • Anonymous. The Wealth of India, A Dictionary of Indian raw Materials and Industrial Products. New Delhi: CSIR, Publication and Information Directorate; 2002. p. 26-31.
  • Rukhsana A. Rub, Asma Mukadam, Javed Pinjari, Ajaz Nathani and Aaisha Sagri, Pharmacognostic and Phytochemical Evaluation of Quirivelia frutescens (Apocynaceae), Asian Journal of Research in Chemistry, 2(4), 2009, 509-512.
  • Harborne JB. Phytochemical methods in: A Guide to Modern Techniques of Plant Analysis. 3rd ed. U.K.: Chapman and Hall, ICMR; 1998. p. 56-99.
  • Mohini Upadhye, Uday Deokate, Murraya koenigii, Research Journal of Pharmacognosy and Phytochemistry, 9(3)2017, 177-181.
  • Wagner H, Baldt S. Plant Drug Analysis,2004, Singapore; 2nd edi.; Springer- Verlag Publication: p.3-6,195-196.
  • Yadav VK, Singh AK, Chaudhari VK, Verma PK, Singh AK, Rajpoot S. TLC Studies and qualitative phytochemical investigations of seeds of Celastrus paniculata willd. Asian J Pharm Technol Innov 2014; 2:7-14.
  • T. Sundarrajan, V. Velmurugan, R.Srimathi, Phytochemical Evaluation and In Vitro Antidiabetic Activity of Ethanolic extract of Alternanthera ficodiaLinn., Research Journal of Pharmacy and Technology , 10(9), 2017, 2981-2983.
  • V.R. Ravikkumar, V. Gopal, N. Ravichandaran, P. Brindha and T. Sudha, Phytochemical Evaluation of Zanthoxylum tetraspermum, Research Journal of Pharmacy and Technology,6(11), 2013, 1200-1206.
  • Kirteebala P. Pawar, Milind J. Bhitre, Priyanka V. Kalamkar, Mohan K. Kale, Pharmacognostical Studies on Leaves of Allamanda cathartica, Research Journal of Pharmacognosy and Phytochemistry, 7(2), 2015, 69-72.
  • Agarwal A, Gupta V, Gupta Amita and Jayalakshmi S, Phytochemical evaluation, Research Journal of Pharmacology and Pharmacodynamics, 1(3), 2009, 134-139.
  • Tauseef Shaikh, Atar Mujum, Khan Wasimuzzama, Preliminary Phytochemical Screening, Asian Journal of Research In Chemistry, 3(4), 2010, 977980.
  • Praveena. A, Sanjayan K. P., Pharmacognostic Studies of Morinda tinctoria, Research Journal of Pharmacognosy and Phytochemsitry, 10(3, 2018, 211-215.
  • Syed Shafeeq. R, Shekshavali. T, Syed Sulthan Ahamed. S. N., Review on Cassia auriculata, Research Journal of Pharmacology and Pharmacodynamics, 2018; 10(3): 141-145.
  • Skand Kumar Mishra, Habitat Economy and Society of the Tribal of Vindhyan region of India, J. Pharmacology and Pharmacodynamics.2018; 10(3): 98-102.
  • Kathiresan K., Bhingam B L., Biology of Mangroves and Mangrove Ecosystem., advances in Marine Biology., 40,81-251.
  • Mukherjee PK. Quality Control of Herbal Drugs: An approach to evaluation of Botanicals.New Delhi, Bussiness Horizons, 2008: p. 184-190.
  • Anonymous, Quality control methods for medicinal plant materials, World Health Organization, Geneva, 1998, 28-30.
  • Nadkarni, A.K., Excoecaria agallocha Linn., Indian Materia Medica, Popular Prakashan, 2009, 532-533.
  • Iyengar M. G., Nayak S.G.K., Anatomy of crude drugs, 11th edition, 2008, 42-54.

Abstract Views: 186

PDF Views: 0




  • Phytochemical and Pharmacognostical Evaluation of Milky Mangrove Excoecaria agallocha Linn

Abstract Views: 186  |  PDF Views: 0

Authors

M. K. Shelar
Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018. (MS), India
M. J. Patil
Marathwada Mitra Mandal's College of Pharmacy, Thergaon, Pune – 411033. (MS), India
S. S. Bhujbal
Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411018. (MS), India

Abstract


Background: Excoecaria agallocha Linn. (Euphorbiaceae) is a small mangrove tree that grows widely in the tidal forests and coastal areas of India. Milky Mangrove is known to have antihyperglycemic, antimicrobial, anti-inflammatory and many other bioactivities. Aim: The present work aims to perform a comprehensive phytochemical and pharmacognostical study of Excoecaria agallocha Linn. Materials and Methods: The Pharmacognostical studies on Excoecaria agallocha including parameters such as morphological evaluation, microscopical evaluation, leaf constants, physicochemical parameters, Thin layer chromatography (TLC) and phytochemical studies were established. Result and Conclusion: Mean ash values (%) were 16.00 (total), 2.75 (acid insoluble), and 13.35 (water soluble). Loss on drying was 0.20%. Microscopy reveals dorsiventral leaf and presence of diacytic stomata in the leaf sample. Quantitative microscopical features such as Stomatal Index, Vein islet number, vein termination number and palisade ratio was determined. The report of TLC indicates presence of Alkaloids and flavonoids. Phytochemical study revealed the presence of alkaloids, steroids, flavonoids, terpenes, tannins and phenolic compounds. Conclusion: The results of the study can serve as a valuable resource of pharmacognostic and phytochemical information. Further work is needed to isolate, characterize, and quantify active constituents present in the leaves of Excoecaria agallocha Linn. by sophisticated techniques.

Keywords


Excoecaria agallocha Linn., Pharmacognostic Evaluation, Phytochemical Evaluation, Thin Layer Chromatography.

References