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Quantitative and Qualitative Analysis of Zingiber officinale as A Crude Drug
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Zingiber officinale has many possibilities as crude drug and also through pharmaceutically extracted medicine. This rhizome belongs to the family Zingiberaceae. Phytochemical constituents of plants are the key ingredients of many pharmaceuticals. The main variation of phytochemicals from crude drugs is their extraction by employing industrially applicable sophisticated techniques for manufacturing various medicaments. Nowadays many crude drugs have been used for synthesizing plants based medicines around the world. The present study aimed at qualitative as well as quantitative estimations of Zingiber officinale by physical tests, chemical estimations, Thin layer chromatography and UV- Visible spectroscopy. The pharmaceutical active ingredient of Zingiber officinale is gingerol whose (Retention factor) Rf value found to be 0.85. The quantitative estiation of gingerol is carried out with the help of double beam UV-VIS Spectrophotometer:5204 at absorption maxima of 282.8 nm. The percentage concentration of gingerol in its Zingiber officinale extract found to be 67.84%.
Keywords
Gingerol, Thin Layer Chromatography, UV-Visible Spectroscopy, Absorption Maxima.
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- Segneanu AE, Dabici A, Zuguang Y, Jianrong L, Grozescu I. Comparative analytical study of active compounds from Zingiber officinale. Optoelectronics and Advanced Materials- Rapid Communications. 2012; 6(5-6): 652-655.
- Nag A, Bandyopadhyay M, Mukherjee A. Antioxidant Activities and Cytotoxicity of Zingiber zerumbet (L.) Smith Rhizome. Journal of Pharmacognosy and Phytochemistry. 2013; 2(3): 102-108.
- Rhizome- From Wikipedia, the free encyclopedia. Wikimedia Foundation, Inc.; 2001. en.wikipedia.org/wiki/Rhizome.
- Shinde SK, Grampurohiot ND, Banerjee SK, Jadhav SL, Gaikwad DD. Development and Validation of UV Spectroscopic Method for the quick estimation of Gingerol from Zingiber officinale rhizome extract. International Research Journal of Pharmacy. 2012; 3(5): 234-237.
- Grant KL, Lutz RB. Ginger. American Journal of Health System Pharmacy. 2000; 57: 945-947.
- Mustafa T, Srivastava KC. Possible leads for arachiodonic acid metabolism altering drugs from natural products. Journal of Drug Delivery.1990; 3: 47-60.
- Jang DS, Han AR, Park G, Jhon GJ, Seo EK. Flavonoids and aromatic compounds from the rhizomes of Zingiber zerumbet. Archives of Pharmacal Research. 2004; 27(3): 386-389.
- Jang DS, Seo EK. Potentially bioactive two new natural sesquiterpenoids from the rhizomes of Zingiber zerumbet. Archives of Pharmacal Research. 2005; 28(3): 294-296.
- Chein T, Chen L, Lee C, Lee F, Wng C. Anti-inflammatory constituents of Zingiber zerumbet. Food Chemistry. 2008; 110(3): 584-589.
- Wholmuth H. Editor. Phytochemistry and Pharmacology of plants from the Ginger family, Zingiberaceae, ePublication@SCU Lismore(Australia). 2008.
- He X, Matthew WB, Lian L, Lin L. High performance liquid chromatography-electrospray mass spectrometric analysis of pungent constituents of ginger. Journal of Chromatography. 1998; 796(2): 327-334.
- Zhang X, Iwaoka WT, Huang AS, Nakamoto ST, Wong R. Gingerol decreases after processing and storage of ginger. Journal of Food Science.1994; 59(6): 1338-1343.
- Indian Pharmacopoeia. Govt. of India. 6th ed. India, Published by the Indian Pharmacopoeia Commission. 2010; pp. 488.
- Shukla SS, Saraf S, Saraf S. Development and Validation of spectrophotometric finger print method of 6-gingerol in herbal formulation: Talisadi Churna. Research Journal of Pharmacy and Technology.2012;5(1):138-140.
- Hussain N, Hashmi AS, Saeed S, Raza S, Qamar S, Mubeen H. Chemical Analysis of trait, Punjab’s Zingiber officinale Rhizome as a crude drug. World Journal of Pharmaceutical Research. 2015; 4(3): 166-176.
- Ginger. Pharmacopeial Forum. 27(5): 3072. www.drugfuture.com/Pharmacopoeia/.../usp32nf27s0_m34965.html.
- Karuppiah P, Rajaram S. Antibacterial effect of Allium sativum and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens. Asian Pacific Journal of Tropical Biomedicine. 2012; 2(8): 597-601.
- Khan R, Zakir M, Afaq SH, Latif A, Khan AU. Activity of sovent extracts of Prosopis spicigera, Zingiber officinale and Trachyspermum ammi against multi drug resistant bacterial and fungal strains. Journal of infection in Developing Countries. 2010; 4(5): 292-300.
- Latona DF, Oyeleke GO, Olayiwola OA. Chemical Analysis of Ginger Root. Journal of Applied Chemistry. 2012; 1(1): 47-49.
- Bal N, Chaubey S, Tiwari RC, Naithani HB. A comparative phytochemical analysis of genuine and market sample of “Gajapippali” W.S.R. to Scindapsus officinalis schott (araceae). International Journal of Ayurveda and Pharma Research. 2016; 4(8): 16-23.
- Bhattacharjee S, Sultana A, Sazzad MH, Islam MA, Ahtashom MM, Asaduzzaman. Analysis of the proximate composition and Energy values of two varieties of Onion (Allium cepa L.) bulbs of different origin; A comparative study. International Journal of Nutrition and Food Sciences. 2013; 2(5): 246-253.
- Momin RK, Kadam VB. Determination of Ash Values of some medicinal plants of genus sesbania of Marathwada region in Maharashtra. Journal of Phytology. 2011; 3(12): 52-54.
- Spices and condiments, Manual of methods of analysis of foods. Food safety and standards authority of India, Ministry of Health and Family Welfare, Published by Government of India, New Delhi. 2012; pp. 19-20, 26-27, 40.
- Moore KP. Plant Analysis Reference Procedures for the Southern Region of the United States. Southern Cooperative Series Bulletin#368,1992; pp. 27-29.
- Itodo AU, Usman A. Sulaiman SB, Itodo H. Color matching estimation of Iron concentrations in Branded Iron Supplements marketed in Nigeria. Advances in Analytical Chemistry. 2012; 2(1): 16-23.
- Niedzielski P, Zielinska-Dawidziak M, Kozak L, Kowalewski P, Szlachetka B, Zalicka S, Wachowiak W. Determination of Iron species in samples of Iron Fortified Food. Food Analytical Methods. 2014; 7: 2023-2032.
- Zade MB. Colorimetric Method for Iron content in Eugenia jambolina and Cordia sebastina rare fruits. Global Journal for Research Analysis. 2017; 6(6): 273-274.
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