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The effect of Morbid Obesity on the Liver Function Enzymes


Affiliations
1 Environmental Research and Studies Centers, Babylon University -51002, Iraq
2 Babylon Technical Institute, Al-Furat Al-Awsat Technical University, 51015, Hilla, Iraq
3 Chemistry Dept., College of Science, University of Babylon, Iraq, Hilla, Iraq
     

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Background: The liver is the major organ in the body and it is considered as an important organ for protein manufacture and detoxification. Liver health is evaluated by study liver function (LFTs) which include TSB, AST, ALT and ALK. The current study is an attempt to understand the correlation between morbid obesity and liver function enzymes. Method: The research population consisted of 67 subjects that divided into two groups; morbidly obese group (41) and the control group (healthy appearance subjects) (26). The levels of serum liver enzymes activities (ALT, AST, ALK) and TSB were determined by suitable kits. Result: In current study no statistically significant differences were observed in AST, ALT and ALK levels between the two types of procedures. The highest differences were noted for TSB levels between obese and individual healthy. While there was an association between the BMI and both AST and ALT; there was no relationship between the body mass index BMI and TSB and ALK. Conclusion: This study showed a correlation between the BMI with AST and ALT of morbidly obese.

Keywords

Obesity, GPT, GOT, ALK, TSB.
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  • The effect of Morbid Obesity on the Liver Function Enzymes

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Authors

Amera Kamal Mohammed
Environmental Research and Studies Centers, Babylon University -51002, Iraq
Thanaa Abdulmahdi Mokif
Babylon Technical Institute, Al-Furat Al-Awsat Technical University, 51015, Hilla, Iraq
Mahmoud Hussein Hadwan
Chemistry Dept., College of Science, University of Babylon, Iraq, Hilla, Iraq

Abstract


Background: The liver is the major organ in the body and it is considered as an important organ for protein manufacture and detoxification. Liver health is evaluated by study liver function (LFTs) which include TSB, AST, ALT and ALK. The current study is an attempt to understand the correlation between morbid obesity and liver function enzymes. Method: The research population consisted of 67 subjects that divided into two groups; morbidly obese group (41) and the control group (healthy appearance subjects) (26). The levels of serum liver enzymes activities (ALT, AST, ALK) and TSB were determined by suitable kits. Result: In current study no statistically significant differences were observed in AST, ALT and ALK levels between the two types of procedures. The highest differences were noted for TSB levels between obese and individual healthy. While there was an association between the BMI and both AST and ALT; there was no relationship between the body mass index BMI and TSB and ALK. Conclusion: This study showed a correlation between the BMI with AST and ALT of morbidly obese.

Keywords


Obesity, GPT, GOT, ALK, TSB.

References